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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Donaron-Met Tablet is used to treat diabetic dyslipidaemia (high cholesterol levels in diabetic patients) and poor blood flow. Also, it may be used to treat polycystic ovarian syndrome. It contains Metformin and Inositol nicotinate which work by reducing the sugar production by cells in the liver, delaying sugar absorption from intestines, improving blood flow and lowering cholesterol levels. In some cases, this medicine may cause side effects such as stomach pain, diarrhoea, nausea, vomiting, and loss of appetite.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Avrohn Pharma (I) Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Donaron-Met Tablet

Donaron-Met Tablet is a combination medicine used to treat diabetic dyslipidaemia (high cholesterol levels in diabetic patients) and poor blood flow. Also, Donaron-Met Tablet may be used to treat the polycystic ovarian syndrome. Diabetic dyslipidaemia is a condition associated with high levels of bad cholesterol (low- density lipoprotein), high triglyceride (a type of fat in the blood) levels and low levels of good cholesterol (high-density lipoprotein) in diabetic patients.

Donaron-Met Tablet is a combination of two drugs, namely: Metformin (antidiabetic) and Inositol nicotinate (vasodilator). Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Inositol nicotinate works by widening blood vessels and lower cholesterol levels.

Take Donaron-Met Tablet as prescribed by your doctor. You are advised to take Donaron-Met Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, diarrhoea, nausea, vomiting, and loss of appetite. Most of these side effects of Donaron-Met Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Donaron-Met Tablet or any other medicines, please tell your doctor. Donaron-Met Tablet is not recommended for children below 10 years of age, as the safety and effectiveness were not established. Avoid breastfeeding while taking Donaron-Met Tablet and consult a doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Donaron-Met Tablet . Avoid alcohol consumption with Donaron-Met Tablet as it may increase the risk of a life-threatening condition known as lactic acidosis. Drive only if you are alert as Donaron-Met Tablet may cause dizziness, weakness or decrease alertness.

Uses of Donaron-Met Tablet

Treatment of Diabetic dyslipidaemia, Polycystic ovarian syndrome (PCOS), Poor blood flow.

Medicinal Benefits

Donaron-Met Tablet is a combination of two drugs, namely: Metformin and Inositol nicotinate used in the treatment of type 2 diabetes, poor blood flow and diabetic dyslipidaemia (high cholesterol levels in diabetic patients). Also, Donaron-Met Tablet may be used to treat the polycystic ovarian syndrome. Metformin decreases the sugar production by cells in the liver and delays sugar absorption from intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Inositol nicotinate works by widening blood vessels and lower cholesterol levels. Proper diet and regular exercise along with Donaron-Met Tablet , will give better results.

Directions for Use

Take Donaron-Met Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Donaron-Met Tablet

  • Stomach pain
  • Diarrhoea
  • Nausea
  • Vomiting
  • Loss of appetite

Drug Warnings

If you are allergic to Donaron-Met Tablet or any other medicines, please tell your doctor. If you have severe infections, uncontrolled diabetes with diarrhoea, lactic acidosis or ketoacidosis (accumulation of ketone bodies in the blood), dehydration, liver, kidney or heart problems, inform your doctor before taking Donaron-Met Tablet . Donaron-Met Tablet is not recommended for children below 10 years of age, as the safety and effectiveness were not established. Avoid breastfeeding while taking Donaron-Met Tablet and consult a doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Donaron-Met Tablet . Avoid alcohol consumption with Donaron-Met Tablet as it may increase the risk of a life-threatening condition known as Lactic acidosis or liver disease. Drive only if you are alert as Donaron-Met Tablet may cause dizziness, weakness or decrease alertness. Maintain a low-fat diet along with Donaron-Met Tablet for effective results. You are recommended to drink plenty of water while taking Donaron-Met Tablet .

Drug Interactions

Drug-Drug Interaction: Donaron-Met Tablet may interact with pain killers (ibuprofen, celecoxib), water tablets (furosemide), antiasthma drugs (terbutaline, salbutamol), antibiotic (rifampicin, trimethoprim), calcium channel blockers (verapamil), antacid (cimetidine), HIV/AIDS drugs (dolutegravir), heart-related medicine (ranolazine), anticancer drug (vandetanib, crizotinib, olaparib), antifungal (isavuconazole), high cholesterol-lowering medicines (simvastatin, atorvastatin, lovastatin, pravastatin), antidiabetic drugs (glimepiride, insulin, glipizide, pioglitazone), blood thinners (heparin, warfarin, enoxaparin).

Drug- Food Interaction: Avoid intake of high-fiber foods after taking Donaron-Met Tablet as they may decrease the concentration of Donaron-Met Tablet . Also, avoid consumption of alcohol with Donaron-Met Tablet as it may increase the risk of a life-threatening condition known as Lactic acidosis or liver disease.

Drug-Disease Interaction: If you have severe infections, uncontrolled diabetes with diarrhoea, lactic acidosis or ketoacidosis (accumulation of ketone bodies in the blood), dehydration, liver, kidney or heart problems, inform your doctor before taking Donaron-Met Tablet .

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • CELECOXIB
  • FUROSEMIDE
  • TERBUTALINE
  • SALBUTAMOL
  • RIFAMPICIN
  • TRIMETHOPRIM
  • VERAPAMIL
  • CIMETIDINE
  • DOLUTEGRAVIR
  • RANOLAZINE
  • VANDETANIB
  • CRIZOTINIB
  • OLAPARIB
  • ISAVUCONAZOLE
  • SIMVASTATIN
  • ATORVASTATIN
  • LOVASTATIN
  • PRAVASTATIN
  • GLIMEPIRIDE
  • INSULIN
  • GLIPIZIDE
  • PIOGLITAZONE
  • HEPARIN
  • WARFARIN
  • ENOXAPARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts and cut down beverages, processed and sugary foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do regular exercises such as swimming, cycling, walking or dancing and focus on losing weight as obesity also raises bad cholesterol and lowers good cholesterol.
  • Avoid consumption of alcohol and quit smoking. 

Special Advise

  • If you are about to undergo any major surgery, X-ray or scan involving contrast medicines containing iodine, please inform your doctor that you are taking Donaron-Met Tablet .
  • Regular blood tests are recommended while taking Donaron-Met Tablet to monitor blood sugar levels and kidney functioning.

Disease/Condition Glossary

Diabetic dyslipidaemia: It is a condition associated with high levels of bad cholesterol (low- density lipoprotein), high triglyceride (a type of fat in the blood) levels and low levels of good cholesterol (high-density lipoprotein) most commonly affecting type-2 diabetic patients. Good cholesterol is good for our heart and helps in reducing the bad cholesterol from our body. On the other hand, excess of bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged that finally contributes to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol containing food/drinks and genetic factors are the primary causes of high cholesterol. 

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Donaron-Met Tablet as it may increase the risk of lactic acidosis or liver disease.

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Pregnancy

Caution

Donaron-Met Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Donaron-Met Tablet is not recommended for breastfeeding mothers. However, please consult a doctor before using Donaron-Met Tablet if you are breastfeeding mother.

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Driving

Caution

Donaron-Met Tablet may cause dizziness, weakness or decrease alertness in some people. Therefore, drive only if you are alert after taking Donaron-Met Tablet .

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Liver

Caution

Take Donaron-Met Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Donaron-Met Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Donaron-Met Tablet if you have severe kidney disease. Regular monitoring of kidney function tests is important if you're taking Donaron-Met Tablet .

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Children

Caution

Donaron-Met Tablet is not recommended for children below 10 years of age, as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

454-456, 2nd Floor, Cheera Bazar, Mumbai-400002
Other Info - DON0116

Author Details

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FAQs

Donaron-Met Tablet is used to treat diabetic dyslipidaemia (high cholesterol levels in diabetic patients) and poor blood flow. Also, it may be used to treat polycystic ovarian syndrome.
Donaron-Met Tablet contains Metformin and Inositol nicotinate. Metformin is an anti-diabetic that reduces sugar production by cells in the liver and delays sugar absorption from intestines. Also, it increases the sensitivity of muscle cells to insulin, enabling these cells to remove sugar more effectively from the blood. Inositol nicotinate is a vasodilator that works by widening blood vessels and lower cholesterol levels.
Donaron-Met Tablet may cause constipation as common adverse effect. You are recommended to drink plenty of fluids while taking Donaron-Met Tablet to prevent constipation. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take Donaron-Met Tablet with high cholesterol lowering medicines such as atorvastatin or simvastatin as it may cause a severe muscle problem called rhabdomyolysis (breakdown of muscle tissue). However, if you experience unexplained muscle pain, weakness or tenderness especially along with fever, dark coloured urine or unusual tiredness, please consult a doctor immediately.
Donaron-Met Tablet should be used with caution in patients suffering from kidney disease as it may worsen the condition. Patients with severe kidney disease should avoid taking Donaron-Met Tablet . However, if you have any kidney problem, please inform your doctor before taking Donaron-Met Tablet and regular monitoring of kidney functioning is recommended while taking Donaron-Met Tablet .
You are recommended to avoid eating foods rich in fat or cholesterol, spicy foods or even hot drinks as they may increase side effects.
You are not recommended to stop taking Donaron-Met Tablet on your own as discontinuing Donaron-Met Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Donaron-Met Tablet , please consult your doctor so that an alternative medicine may be prescribed.

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