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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dolokind-MR Tablet is used for pain relief and muscle relaxation. It works by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins) and work on the central nervous system (CNS) to relax muscles, relieving pain and stiffness caused by muscle strains and sprains. It may cause common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Dolokind-MR Tablet 10's, Pack of 10 TABLETS
Dolokind-MR Tablet 10's, Pack of 10 TABLETS
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Prescription drug

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Synonym :

ACECLOFENAC+ACETAMINOPHEN+CHLORZOXAZONE

Composition :

ACECLOFENAC-100MG + CHLORZOXAZONE-250MG + PARACETAMOL-325MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Dolokind-MR Tablet is used for pain relief and muscle relaxation. Muscle pain (myalgia) is widespread and generally refers to uncomfortable sensations in the muscles, which can be due to illness, injury or excessive exercise. It can be continuous or can also occur at intervals.

Dolokind-MR Tablet contains three medicines, namely: Aceclofenac (pain killer), Paracetamol (fever reducer/mild pain reliever) and Chlorzoxazone (muscle relaxant). These work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins) and work on the central nervous system (CNS) to relax muscles, relieving pain and stiffness caused by muscle strains and sprains.

Dolokind-MR Tablet can be taken as your doctor advises for the best results. Common side effects of Dolokind-MR Tablet include nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. If any of these side effects worsen or subside, please visit your doctor immediately.

Dolokind-MR Tablet should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Dolokind-MR Tablet as it may increase drowsiness and dizziness. Excess of Paracetamol (Acetaminophen) intake can cause liver damage, so its dose should not exceed more than 4 gm per day.

Treatment of Musculoskeletal pain
Take Dolokind-MR Tablet as advised by your doctor. Preferably take it with a meal to avoid an upset stomach. Swallow it as a whole; do not chew or crush it. Keep this medicine out of sight and reach of children.

Aceclofenac and Paracetamol (Acetaminophen) together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused by muscle strains and sprains.

Dolokind-MR Tablet contains three medicines, namely: Aceclofenac (pain killer), Paracetamol (fever reducer/mild pain reliever) and Chlorzoxazone (muscle relaxant). These work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins) and work on the central nervous system (CNS) to relax muscles, relieving pain and stiffness caused by muscle strains and sprains.
Store in a cool and dry place away from sunlight
  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Tiredness
  • Sleepiness
Do not take more than the prescribed dose of Dolokind-MR Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Dolokind-MR Tablet should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Dolokind-MR Tablet as it may increase drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess paracetamol intake can cause liver damage, so its dose should not exceed more than 4 gm per day.

verifiedApollotooltip
AceclofenacAtenolol
Severe
ChlorzoxazoneMorphine
Severe

Drug-Drug Interactions

AceclofenacAtenolol
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Atenolol with Dolokind-MR Tablet 10's could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Dolokind-MR Tablet 10's, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ChlorzoxazoneMorphine
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Using Morphine together with Dolokind-MR Tablet 10's can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Dolokind-MR Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ChlorzoxazoneTapentadol
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Taking Tapentadol with Dolokind-MR Tablet 10's can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Dolokind-MR Tablet 10's with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of ketamine and Dolokind-MR Tablet 10's may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Dolokind-MR Tablet 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Dolokind-MR Tablet 10's and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Dolokind-MR Tablet 10's and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Mipomersen with Dolokind-MR Tablet 10's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Dolokind-MR Tablet 10's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Dolokind-MR Tablet 10's and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Dolokind-MR Tablet 10's and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Dolokind-MR Tablet 10's may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Dolokind-MR Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Lomitapide and Dolokind-MR Tablet 10's may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Dolokind-MR Tablet 10's and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Dolokind-MR Tablet 10's:
Co-administration of Teriflunomide with Dolokind-MR Tablet 10's may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Dolokind-MR Tablet 10's with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Try to increase the consumption of calcium and vitamin D, as recommended, as part of a healthy bone diet.
  • Omega-3 fatty acid oil enriched food should be included in your daily meal to keep joints healthy.
  • Connective tissues are the “cellular glue” that connects and supports vital organs in the body. This connective tissue is comprised of proteins like collagen and elastin. Proteins are required to keep your muscles healthy, so non-vegetarians should eat high-protein diets like fish (salmon, sardines, and tuna), chicken, and eggs. Meanwhile, legumes, nuts, seeds, and dairy items (milk, yoghurt, cheese) are recommended for a vegetarian person. 
  • Magnesium, Vitamin K and Zinc-enriched foods can help keep your bones and muscles healthy, so their intake should be enhanced in your daily diet plan. 
  • Physical activities like Tai chi, Yoga, swimming and walking have shown improvement in managing muscle pain. 
  • Do not sit for a longer duration. Try to take a gap of 10 minutes by brisk walking or stretching.
No
ANALGESICS

Dolokind-MR Tablet Substitute

Substitutes safety advice

  • Aceelo Tablet 10's

    ₹10.00per tablet

  • Acemiz-MR Tablet 10's

    ₹10.80per tablet

  • Movexx MR Tablet 10's

    by AYUR

    ₹11.97per tablet

  • Aldigesic MR Tablet 10's

    ₹9.90per tablet

  • Osteofast-MR Tablet 10's

    ₹8.73per tablet
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Acimol-MR Tablet 10's

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Acewok-MR Tablet 10's

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Nelnac MR Tablet 10's

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Mahanac-Mr Tablet

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Unsafe

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Consult your doctor

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Consult your doctor

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Caution

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Caution

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Caution

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Safe if prescribed

FAQs

Dolokind-MR Tablet is used to relieve musculoskeletal pain. It works by blocking the action of chemical messengers that cause pain.
No, do not suddenly stop taking Dolokind-MR Tablet . Abrupt stopping of medication may worsen your condition. However, if you want to stop taking this medicine, consult your doctor.
Yes, Dolokind-MR Tablet is known to cause nausea or vomiting. You should take Dolokind-MR Tablet with milk or food to avoid the same. In case you are still experiencing excessive nausea while consuming Dolokind-MR Tablet , speak with your doctor right away.
No, Dolokind-MR Tablet does not cure rheumatoid arthritis; instead, it helps reduce the pain and inflammation caused by it for a short time as Dolokind-MR Tablet is an analgesic.
Patients with mild to moderate renal impairment should be kept under surveillance. The lowest effective dose should be used and renal function monitored regularly. Effects on renal function are usually reversible on withdrawal of Dolokind-MR Tablet .
No, Dolokind-MR Tablet is not recommended for stomach pain. This medication can increase the secretion of stomach acid and can cause stomach ulcers and bleeding. So, if you have any gastrointestinal ulcer, bleeding problem or liver issue, speak to your doctor before using Dolokind-MR Tablet .
The common side effects of Dolokind-MR Tablet include nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. If any of these side effects bother you, please consult your doctor.
Dolokind-MR Tablet is used to relieve pain and inflammation. While it can help with certain types of pain, it may not be the best choice for a toothache. For a toothache, your best bet is usually a dental consultation to determine the underlying cause and appropriate treatment.
Dolokind-MR Tablet itself contains painkillers. Taking additional painkillers with Dolokind-MR Tablet can lead to overlapping side effects, increased risk of adverse reactions, and potential interactions. Please consult your doctor if you have severe pain so they can assess your situation and provide personalized guidance for safe and effective pain management.
Dolokind-MR Tablet is a combination medication that contains three active ingredients: Aceclofenac, a pain killer; Paracetamol, a fever reducer and mild pain reliever; and Chlorzoxazone, a muscle relaxant. This medication primarily treats musculoskeletal pain, including conditions such as muscle strain, sprains, and injuries.
To alleviate muscle pain, consider combining Dolokind-MR Tablet with gentle stretches, warm or cold compresses, and gentle exercises like yoga or swimming. Additionally, prioritize rest, maintain proper posture, and engage in stress-reducing activities like meditation or deep breathing. Adequate sleep is also essential for muscle recovery and pain management. By incorporating these lifestyle changes with Dolokind-MR Tablet , you can effectively manage musculoskeletal pain and promote overall well-being.
Dolokind-MR Tablet contains Aceclofenac, Paracetamol, and Chlorzoxazone, which are not typically considered addictive medications.
When your pain subsides, consult your doctor before stopping Dolokind-MR Tablet . They'll assess your progress and provide personalized advice on the next steps, including gradually tapering off the medication or lifestyle changes to maintain pain relief. This ensures the most effective treatment and minimizes pain recurrence.
Yes, Dolokind-MR Tablet can cause dizziness as a possible side effect. The medication combination in Dolokind-MR Tablet , including Aceclofenac, Paracetamol, and Chlorzoxazone, can cause dizziness or lightheadedness in some individuals.
Yes, Dolokind-MR Tablet can cause liver damage as a possible side effect, specifically due to the presence of Paracetamol. Taking high doses of Paracetamol can cause liver injury or damage. However, when taken as directed, the risk of liver damage is low. Your doctor will monitor your liver function and adjust your treatment plan as needed. If you experience symptoms like yellowing skin, dark urine, or abdominal pain, seek medical attention immediately.
Dolokind-MR Tablet typically takes effect within 30 minutes to 1 hour, offering quick pain relief. The medication's anti-inflammatory and muscle-relaxing properties may become noticeable within 1-2 hours. While some benefits may be felt shortly after taking Dolokind-MR Tablet , it may take several hours to experience the full therapeutic effects. Always consult your healthcare provider if you have questions or don't feel better.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Do not take a double dose to make up for a missed one.
It is not recommended to take a higher-than-recommended dose. Taking more than the recommended dosage does not provide additional relief or is more effective, and it can increase the risk of adverse effects.
Certain individuals should avoid taking Dolokind-MR Tablet , including those with a history of allergic reactions to the medication, active stomach ulcers, or severe liver or kidney problems. Pregnant or breastfeeding women should consult their doctor before use. Additionally, Dolokind-MR Tablet should not be combined with other pain relievers or blood thinners, and people with asthma or a history of allergic reactions to similar medications should exercise caution.
Dolokind-MR Tablet has an expiration date, just like all medications. Using it after this date can reduce its effectiveness or cause harmful side effects. Always check the expiration date on the packaging or label to ensure safe and effective use.
Dolokind-MR Tablet contains three medicines: Aceclofenac (pain killer), Paracetamol (fever reducer/mild pain reliever), and Chlorzoxazone (muscle relaxant). These work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins) and work on the central nervous system (CNS) to relax muscles, relieving pain and stiffness caused by muscle strains and sprains.
Do not take any other medication with Dolokind-MR Tablet unless your doctor has advised you to do so after checking for potential interactions and benefits. Your doctor will ensure that the combination is safe and effective for you, so always consult them before taking any other medication with Dolokind-MR Tablet .
Certain individuals are advised not to take Dolokind-MR Tablet , including those with a history of allergic reactions to Dolokind-MR Tablet , severe liver or kidney issues, and pregnant or breastfeeding women unless approved by their healthcare provider. Individuals taking specific medications that may interact with Dolokind-MR Tablet should exercise caution. To ensure safe usage, consult your healthcare provider for personalized guidance tailored to your unique medical profile, lifestyle, and current medications.
No. Do not use it during pregnancy. Dolokind-MR Tablet is contraindicated to pregnant and breastfeeding women. If you are pregnant, consult your healthcare provider for alternative treatments that are safe for you and your baby.
Accidental overdose of Dolokind-MR Tablet can be harmful and requires immediate medical attention. Take more than the prescribed dose. You may experience serious side effects, including liver damage, allergic reactions, mouth, face, or throat swelling, difficulty breathing, skin rash, or itching. If you experience any side effects or suspect an overdose, seek medical help right away.
India
208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - DOL0020
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Zandu Balm, 8 ml

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Reference

  1. https://www.drugs.com/pro/chlorzoxazone.html <br />
  2. https://www.medicines.org.uk/emc/files/pil.4240.pdf <br />
  3. https://www.medicines.org.uk/emc/files/pil.5164.pdf
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