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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dixin 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. It contains Digoxin, which works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DIGOXIN-0.25MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dixin 0.25 mg Tablet

Dixin 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which your heart beats irregularly, too fast or too slow.

Dixin 0.25 mg Tablet contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduce the rate of heart contractions. Dixin 0.25 mg Tablet works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Take Dixin 0.25 mg Tablet as prescribed. Your doctor will recommend how often you take Dixin 0.25 mg Tablet based on your medical condition. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Most of these side effects of Dixin 0.25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Dixin 0.25 mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Regular blood tests are recommended by your doctor while taking Dixin 0.25 mg Tablet to monitor the amount of Dixin 0.25 mg Tablet in the bloodstream as its toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food) or any lung or kidney disease, please inform your doctor before taking Dixin 0.25 mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin 0.25 mg Tablet has a very narrow therapeutic index. It means small differences in the dose of drugs in the body may lead to life-threatening conditions or serious side effects. This makes its use limited and requires close monitoring by doctors like regular electrocardiogram (ECG). So, try not to self-medicate and suggest Dixin 0.25 mg Tablet to others.

Uses of Dixin 0.25 mg Tablet

Treatment of Irregular heartbeats, Prevention of heart failure.

Directions for Use

Take Dixin 0.25 mg Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Dixin 0.25 mg Tablet is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Dixin 0.25 mg Tablet increases the force with which the heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, it slows down the rate at which the heart beats and makes the heart rate normal. Dixin 0.25 mg Tablet improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

How Dixin 0.25 mg Tablet Works

Dixin 0.25 mg Tablet contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduce the rate of heart contractions. Dixin 0.25 mg Tablet works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dixin 0.25 mg Tablet

  • Feeling confused
  • Dizziness
  • Nausea or vomiting
  • Loss of appetite
  • Diarrhoea
  • Changes in your vision (including blurred vision and not being able to look at bright light)

What if I have taken an overdose of Dixin 0.25 mg Tablet

Do not take more than the prescribed dose of Dixin 0.25 mg Tablet as it may cause overdose. The symptoms of overdose include loss of appetite, vomiting, nausea and feeling tired. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Dixin 0.25 mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Avoid intake of alcohol with Dixin 0.25 mg Tablet as it may increase the risk of drowsiness. Dixin 0.25 mg Tablet may cause vision problems in some people. Make sure you are not affected before driving. Regular blood tests are recommended by your doctor while taking Dixin 0.25 mg Tablet to monitor the amount of digoxin in blood as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Dixin 0.25 mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin 0.25 mg Tablet has a narrow therapeutic index which makes its use limited and requires close monitoring as small change in dose or blood concentration may lead to severe adverse effects, and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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DigoxinFamotidine
Severe
DigoxinClarithromycin
Severe

Drug-Drug Interactions

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DigoxinFamotidine
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Dixin 0.25 mg Tablet 10's and Famotidine may increase the level or effect of Dixin 0.25 mg Tablet 10's.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25 mg Tablet 10's and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
DigoxinClarithromycin
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Clarithromycin with Dixin 0.25 mg Tablet 10's may increase the blood levels and effects of Dixin 0.25 mg Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Dixin 0.25 mg Tablet 10's if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of excessive Dixin 0.25 mg Tablet 10's levels such as diarrhea, nausea, loss of appetite, vomiting, visual disturbances, and an abnormally fast or slow or uneven heartbeat. Do not discontinue the medication without consulting a doctor.
DigoxinGlycopyrronium bromide
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Dixin 0.25 mg Tablet 10's and Glycopyrronium bromide may increase the serum concentration of Dixin 0.25 mg Tablet 10's and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25 mg Tablet 10's and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DigoxinCalcium carbonate
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Calcium carbonate and Dixin 0.25 mg Tablet 10's may increase the calcium levels may increase the effects of Dixin 0.25 mg Tablet 10's

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Dixin 0.25 mg Tablet 10's if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
DigoxinSucralfate
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Sucralfate together with Dixin 0.25 mg Tablet 10's may decrease the effects of Dixin 0.25 mg Tablet 10's.

How to manage the interaction:
If you are supposed to take Dixin 0.25 mg Tablet 10's and Sucralfate together, your doctor may adjust the dose to safely use both medications. Do not discontinue the medication without consulting a doctor.
DigoxinAdenosine
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Adenosine with Dixin 0.25 mg Tablet 10's shows additive effects on the heart and may cause abnormal heart rhythms.

How to manage the interaction:
Taking Adenosine with Dixin 0.25 mg Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
DigoxinAtazanavir
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Coadministration of Dixin 0.25 mg Tablet 10's and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25 mg Tablet 10's and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
DigoxinLapatinib
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Dixin 0.25 mg Tablet 10's and Lapatinib may increase the blood levels and effects of Dixin 0.25 mg Tablet 10's.

How to manage the interaction:
If you are supposed to take Dixin 0.25 mg Tablet 10's and Lapatinib together, a doctor may adjust the dose or monitor more frequently to safely use both medications. If you experience diarrhea, nausea, loss of appetite, vomiting, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, contact a doctor as these may be signs and symptoms of excessive Dixin 0.25 mg Tablet 10's levels. Do not discontinue the medication without consulting a doctor.
DigoxinCalcium gluconate
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Calcium gluconate with Dixin 0.25 mg Tablet 10's may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Dixin 0.25 mg Tablet 10's if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
DigoxinAmiodarone
Severe
How does the drug interact with Dixin 0.25 mg Tablet 10's:
Co-administration of Amiodarone with Dixin 0.25 mg Tablet 10's can increase Dixin 0.25 mg Tablet 10's levels which can lead to severe side effects.

How to manage the interaction:
Taking Amiodarone with Dixin 0.25 mg Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, visual disturbances, slow pulse, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dixin 0.25 mg Tablet 10's with Grapefruit and Grapefruit juice may increase the side effects of Dixin 0.25 mg Tablet 10's. Consuming Grapefruit and grapefruit juice should be avoided while taking Dixin 0.25 mg Tablet 10's.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.

  • Do the regular exercise as it helps to lower blood pressure and keeps blood vessels and heart in good condition.

  • Quit smoking as smoking increases blood pressure and heart rate.

  • Eat balanced and healthy diet which includes plenty of vegetables, fruits, low fat or fat free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Dixin 0.25 mg Tablet Substitute

Substitutes safety advice
  • Lanoxin Tablet 10's

    1.31per tablet
  • Digoxin-0.25 Tablet 10's

    1.17per tablet
  • Digon 0.25 mg Tablet 10's

    1.26per tablet
  • Zigoxin 0.25 mg Tablet 10's

    1.44per tablet
  • DIXIN 0.25MG INJECTION 2ML

    3.75per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dixin 0.25 mg Tablet as it may increase drowsiness and reduce the amount of Dixin 0.25 mg Tablet in blood leading to abnormal heart function.

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Pregnancy

Caution

Tablet: It is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Tablet: It is safe for breastfeeding mothers if prescribed by a doctor.

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Driving

Caution

Dixin 0.25 mg Tablet may cause dizziness, yellow or blurred vision in some people. So, make sure you are not affected before driving or operating machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Dixin 0.25 mg Tablet in patients with Liver problems, please consult a doctor.

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Kidney

Caution

Take Dixin 0.25 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Paediatric solution is to be used in children in doses as prescribed by a child specialist.

FAQs

Dixin 0.25 mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. It works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.
It may take several weeks for Dixin 0.25 mg Tablet to show its effect. You are recommended to continue taking Dixin 0.25 mg Tablet for as long as your doctor prescribes it and do not stop taking Dixin 0.25 mg Tablet suddenly as it may worsen your heart problems. However, if you experience any difficulty while taking Dixin 0.25 mg Tablet , please consult your doctor.
Yes, Dixin 0.25 mg Tablet may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Dixin 0.25 mg Tablet to experience this side effect. You are recommended to drink plenty of fluids to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsen, please consult your doctor.
Yes, Dixin 0.25 mg Tablet may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.
No, you can eat normally. However, a balanced and healthy diet are advised for effective results.
You are not recommended to take more than the prescribed dose of Dixin 0.25 mg Tablet as it may cause Dixin 0.25 mg Tablet toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances (more than usual yellow-green). However, if you experience any of these symptoms while taking Dixin 0.25 mg Tablet , please consult a doctor immediately.
No, you are not recommended to take amiodarone with Dixin 0.25 mg Tablet as co-administration of these two medicines may increase the levels of Dixin 0.25 mg Tablet in the blood resulting in Dixin 0.25 mg Tablet toxicity. However, please consult a doctor before taking other medicines with Dixin 0.25 mg Tablet so that the dose may be adjusted appropriately.
You are recommended to avoid taking Dixin 0.25 mg Tablet if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).
Dixin 0.25 mg Tablet contains digoxin (a cardiac glycoside) that works directly on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.
The common side effects of Dixin 0.25 mg Tablet include diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat, and skin rash. If these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DIX0005

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