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Digitran 0.25mg Tablet

Digitran 0.25mg Tablet

Prescription drug
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Composition

DIGOXIN-0.25MG

Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Digitran 0.25mg Tablet

Digitran 0.25mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which your heart beats irregularly, too fast or too slow.

Digitran 0.25mg Tablet contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduce the rate of heart contractions. Digitran 0.25mg Tablet works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Take Digitran 0.25mg Tablet as prescribed. Your doctor will recommend how often you take Digitran 0.25mg Tablet based on your medical condition. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Most of these side effects of Digitran 0.25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Digitran 0.25mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Regular blood tests are recommended by your doctor while taking Digitran 0.25mg Tablet to monitor the amount of Digitran 0.25mg Tablet in the bloodstream as its toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food) or any lung or kidney disease, please inform your doctor before taking Digitran 0.25mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Digitran 0.25mg Tablet has a very narrow therapeutic index. It means small differences in the dose of drugs in the body may lead to life-threatening conditions or serious side effects. This makes its use limited and requires close monitoring by doctors like regular electrocardiogram (ECG). So, try not to self-medicate and suggest Digitran 0.25mg Tablet to others.

Uses of Digitran 0.25mg Tablet

Treatment of Irregular heartbeats, Prevention of heart failure.

Medicinal Benefits

Digitran 0.25mg Tablet is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Digitran 0.25mg Tablet increases the force with which the heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, it slows down the rate at which the heart beats and makes the heart rate normal. Digitran 0.25mg Tablet improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

Directions for Use

Take Digitran 0.25mg Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Digitran 0.25mg Tablet

  • Feeling confused
  • Dizziness
  • Nausea or vomiting
  • Loss of appetite
  • Diarrhoea
  • Changes in your vision (including blurred vision and not being able to look at bright light)

Drug Warnings

If you are known to be allergic to Digitran 0.25mg Tablet or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Avoid intake of alcohol with Digitran 0.25mg Tablet as it may increase the risk of drowsiness. Digitran 0.25mg Tablet may cause vision problems in some people. Make sure you are not affected before driving. Regular blood tests are recommended by your doctor while taking Digitran 0.25mg Tablet to monitor the amount of digoxin in blood as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Digitran 0.25mg Tablet so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Digitran 0.25mg Tablet has a narrow therapeutic index which makes its use limited and requires close monitoring as small change in dose or blood concentration may lead to severe adverse effects, and overdose may lead to life-threatening reactions.

Drug Interactions

Drug-Drug Interaction: Digitran 0.25mg Tablet may have interaction with medicines used to treat irregular heartbeat (adenosine, amiodarone, dolasetron, quinidine), cardiac stimulants (arbutamine), HIV/AIDS drugs (atazanavir, saquinavir), anticancer drugs (ceritinib, lapatinib), antibiotics (clarithromycin), immunosuppressants (fingolimod), antidepressants (flibanserin), antifungal drugs (itraconazole) and calcium supplements (calcium chloride, calcium gluceptate, calcium gluconate).

Drug- Food Interaction: Digitran 0.25mg Tablet may interact with alcohol. Therefore, avoid alcohol intake while taking Digitran 0.25mg Tablet.

Drug-Disease Interaction: If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Digitran 0.25mg Tablet.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • QUINIDINE
  • ATAZANAVIR
  • SAQUINAVIR
  • CLARITHROMYCIN
  • ITRACONAZOLE
  • ADENOSINE
  • DOLASETRON
  • ARBUTAMINE
  • CERITINIB
  • LAPATINIB
  • FINGOLIMOD
  • FLIBANSERIN
  • CALCIUM CHLORIDE
  • CALCIUM GLUCEPTATE
  • CALCIUM GLUCONATE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.

  • Do the regular exercise as it helps to lower blood pressure and keeps blood vessels and heart in good condition.

  • Quit smoking as smoking increases blood pressure and heart rate.

  • Eat balanced and healthy diet which includes plenty of vegetables, fruits, low fat or fat free products.

Special Advise

  • Regular blood tests are advised while taking Digitran 0.25mg Tablet to monitor digoxin levels in the blood, potassium levels and kidney functioning.
  • Low salt diet and regular exercise are recommended along with Digitran 0.25mg Tablet for effective results.
  • Regular electrocardiogram (ECG) should be done to see the effect of Digitran 0.25mg Tablet on your heartbeat.

Disease/Condition Glossary

Heart failure: It is a chronic condition in which the heart is unable to pump blood as effectively as it should. Heart failure may occur due to certain conditions like high blood pressure, swelling or damage of heart muscle, faulty heart valves or narrow arteries in the heart. Symptoms of heart failure include shortness of breath, tiredness, fast heartbeat and swollen legs.

Arrhythmia (irregular heartbeat) is a condition in which your heart beats irregularly, too fast or too slow. Symptoms of irregular heartbeat include chest pain, shortness of breath, and fast or slow heartbeat. 60 to 100 beats per minute is generally considered as normal heart rate.

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Digitran 0.25mg Tablet as it may increase drowsiness and reduce the amount of Digitran 0.25mg Tablet in blood leading to abnormal heart function.

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Pregnancy

Caution

Tablet: It is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Tablet: It is safe for breastfeeding mothers if prescribed by a doctor.

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Driving

Caution

Digitran 0.25mg Tablet may cause dizziness, yellow or blurred vision in some people. So, make sure you are not affected before driving or operating machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Digitran 0.25mg Tablet in patients with Liver problems, please consult a doctor.

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Kidney

Caution

Take Digitran 0.25mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Paediatric solution is to be used in children in doses as prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - DIGI278

Author Details

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FAQs

Digitran 0.25mg Tablet is used to treat irregular heartbeats and manage the symptoms of heart failure. It works on the heart muscle directly and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.
It may take several weeks for Digitran 0.25mg Tablet to show its effect. You are recommended to continue taking Digitran 0.25mg Tablet for as long as your doctor prescribes it and do not stop taking Digitran 0.25mg Tablet suddenly as it may worsen your heart problems. However, if you experience any difficulty while taking Digitran 0.25mg Tablet, please consult your doctor.
Yes, Digitran 0.25mg Tablet may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Digitran 0.25mg Tablet to experience this side effect. You are recommended to drink plenty of fluids to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsen, please consult your doctor.
Yes, Digitran 0.25mg Tablet may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.
No, you can eat normally. However, a balanced and healthy diet are advised for effective results.
You are not recommended to take more than the prescribed dose of Digitran 0.25mg Tablet as it may cause Digitran 0.25mg Tablet toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances (more than usual yellow-green). However, if you experience any of these symptoms while taking Digitran 0.25mg Tablet, please consult a doctor immediately.
No, you are not recommended to take amiodarone with Digitran 0.25mg Tablet as co-administration of these two medicines may increase the levels of Digitran 0.25mg Tablet in the blood resulting in Digitran 0.25mg Tablet toxicity. However, please consult a doctor before taking other medicines with Digitran 0.25mg Tablet so that the dose may be adjusted appropriately.
You are recommended to avoid taking Digitran 0.25mg Tablet if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).

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