apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Diaceten ACE 100mg/50mg Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains Aceclofenac and Diacerein which work by blocking the action of chemical messengers that cause pain and specific proteins that cause degradation of cartilage. This medicine may sometimes cause side effects such as nausea, vomiting, indigestion, heartburn, stomach pain, diarrhoea, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Diaceten ACE 100mg/50mg Tablet

Diaceten ACE 100mg/50mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain, redness and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Osteoarthritis is a disease characterized by the degeneration of cartilage and its underlying bone within a joint, as well as bony overgrowth. Ankylosing spondylitis is a rare type of arthritis that causes pain and stiffness in your spine. Rheumatoid arthritis is an autoimmune disease in which the immune system of the body attacks its own cells and causes damage, thereby causing joint pain with inflammation.

Diaceten ACE 100mg/50mg Tablet is composed of two medicines: Aceclofenac and Diacerine. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Diacerine works by blocking the actions of a certain specific protein that causes swelling, pain, and degradation of cartilage at bone joints. So this Diaceten ACE 100mg/50mg Tablet both in combination reduces pain and inflammation.

Take Diaceten ACE 100mg/50mg Tablet as prescribed by the doctor. You can take Diaceten ACE 100mg/50mg Tablet with or after food. You are advised to take Diaceten ACE 100mg/50mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, indigestion, heartburn, stomach pain, diarrhea, loss of appetite, and intense yellow urine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Diaceten ACE 100mg/50mg Tablet if you are allergic to it. Tell your doctor if you are using any other medicines other than the Diaceten ACE 100mg/50mg Tablet. Inform your doctor if you are pregnant/planning to get pregnant/breastfeeding women. Diaceten ACE 100mg/50mg Tablet should be used with caution in bleeding disorders, kidney diseases, liver diseases, asthma, people who are in antibiotic therapy, and heart-surgery patients.

Uses of Diaceten ACE 100mg/50mg Tablet

Treatment of Osteoarthritis, Rheumatoid arthritis and ankylosing spondylitis

Medicinal Benefits

Diaceten ACE 100mg/50mg Tablet is composed of two medicines: Aceclofenac and Diacerine belong to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Diacerine works by blocking the actions of a certain specific protein that causes swelling, and pain, and reduces friction in the joints by the building of cartilage (the soft connective tissue in the bones near the joints).

Directions for Use

Take Diaceten ACE 100mg/50mg Tablet in the dose and for the duration advised by your doctor. Swallow it as a whole with a glass of water. Do not chew, crush or break it. Diaceten ACE 100mg/50mg Tablet is to be taken with food, which helps to prevent any potential gastric irritation the drug might cause when taken empty stomach.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diaceten ACE 100mg/50mg Tablet

  • Nausea
  • Vomiting
  • Indigestion
  • Heartburn
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Intense yellow urine

Drug Warnings

Do not take Diaceten ACE 100mg/50mg Tablet if you are allergic to it. Tell your doctor if you are using any other medicines other than the Diaceten ACE 100mg/50mg Tablet. Inform your doctor if you are pregnant/planning to get pregnant/breastfeeding women. Diaceten ACE 100mg/50mg Tablet should be used with caution in bleeding disorders, kidney diseases, liver diseases, asthma, and heart-surgery patients. Diaceten ACE 100mg/50mg Tablet should be used with caution in patients having irritable bowel or other associated conditions of the gastrointestinal tract due to an increase in the risk of adverse effects. Avoid consuming alcohol while taking Diaceten ACE 100mg/50mg Tablet as it can increase your risk of stomach problems. Your doctor may regularly monitor your kidney function, liver function, blood sugar level, and levels of blood components if you are taking this Diaceten ACE 100mg/50mg Tablet for long-term treatment. Diaceten ACE 100mg/50mg Tablet should not be taken with antibiotics since the risk of gastric irritation and persistent diarrhea is significantly more.

Drug Interactions

Drug-Drug Interaction: Diaceten ACE 100mg/50mg Tablet interact with antidepressants (lithium), cardiac glycoside (digoxin), antibiotic (amoxicillin), antacids (aluminium hydroxide), corticosteroids (prednisone), anti-hypertensives (enalapril, lisinopril, losartan, candesartan, hydralazine), blood-thinners (warfarin).

Drug-Food Interaction: Drugs may interact with foods rich in fibres (beans, lentils)  and phytates (grains, nuts, legumes)

Drug-Disease Interaction: Patients with liver disease, bleeding disorder, kidney disease, asthma, irritable bowel disorder, heart disease and alcoholism should not take Diaceten ACE 100mg/50mg Tablet as it has a risk of causing derangement in liver functions.

Drug-Drug Interactions Checker List

  • LITHIUM
  • DIGOXIN
  • AMOXICILLIN
  • ALUMINIUM HYDROXIDE
  • PREDNISONE
  • ENALAPRIL
  • LISINOPRIL
  • CANDESARTAN
  • HYDRALAZINE
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.

  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Special Advise

  • The components of Diaceten ACE 100mg/50mg Tablet have the tendency to cause stomach upset. Thus, it is recommended to consume Diaceten ACE 100mg/50mg Tablet with meals to minimize gastric side effects. If you have a diagnosis of peptic ulcer, Diaceten ACE 100mg/50mg Tablet is best avoided unless prescribed by your doctor.

  • Avoid consuming alcohol while Diaceten ACE 100mg/50mg Tablet as it can increase your risk of stomach problems.

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the breakdown of a cartilage protective covering causes the two ends of the joints to come together. The lack of this protective covering causes the joints to rub against one another, causing discomfort and stiffness. Osteoarthritis signs and symptoms include pain, stiffness, swelling, and tenderness. Age is the primary cause of osteoarthritis. Osteoarthritis, also referred to as a degenerative disease because it causes the joints to wear out as a person ages, is more likely to develop as you get older. Past injuries like torn ligaments, dislocated joints, and torn cartilage are additional causes.
Rheumatoid arthritis: Joint pain and damage are caused by an auto-immune disease in which the immune system of the body attacks its own tissue. Rheumatoid arthritis symptoms include joint pain, stiffness, swelling, deformities, and loss of joint function.

Ankylosing spondylitis: The spine becomes painful and stiff as a result. The lower back is where the pain typically first appears, but it can also affect the neck, damaged joints, or other areas of the body. Reduced flexibility, which typically causes a hunched-forward posture, and pain in the back and joints are all signs of ankylosing spondylitis.

bannner image

Alcohol

Caution

Consumption of alcohol with Diaceten ACE 100mg/50mg Tablet is not recommended during treatment with Diaceten ACE 100mg/50mg Tablet due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, and fever. So please consult your doctor before taking Diaceten ACE 100mg/50mg Tablet, if you have a habit of drinking alcohol.

bannner image

Pregnancy

Caution

Diaceten ACE 100mg/50mg Tablet use during pregnancy is not recommended unless your doctor believes it is necessary. (It must not be used during the final three months of pregnancy.) Please consult your doctor before using this medicine if you are pregnant or planning a pregnancy.

bannner image

Breast Feeding

Caution

Diaceten ACE 100mg/50mg Tablet is not recommended for use in breastfeeding as it is not known whether this medicine passes into breast milk. Your doctor may prescribe a safer alternative medicine based on the clinical condition.

bannner image

Driving

Caution

Diaceten ACE 100mg/50mg Tablet may decrease alertness, affect your vision or make you sleepy and dizzy. Do not drive if these symptoms occur after taking Diaceten ACE 100mg/50mg Tablet.

bannner image

Liver

Caution

Diaceten ACE 100mg/50mg Tablet should be used with caution in patients with liver disease due to the increased risk of serious side effects. Close monitoring of liver function, appropriate dose adjustments or replacement with alternative medicine may be required based on your clinical condition.

bannner image

Kidney

Caution

Diaceten ACE 100mg/50mg Tablet should be used with caution in patients with kidney diseases due to the increased risk of serious side effects. Close monitoring of kidney function, appropriate dose adjustments or replacement with alternative medicine may be required based on your clinical condition.

bannner image

Children

Caution

The safety and efficacy of Diaceten ACE 100mg/50mg Tablet in children have not been established. Diaceten ACE 100mg/50mg Tablet is not recommended for use in children.

Country of origin

India
Other Info - DI22273

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Diaceten ACE 100mg/50mg Tablet is used to relieve pain and inflammation (swelling) in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Diaceten ACE 100mg/50mg Tablet is composed of two medicines: Aceclofenac and Diacerine. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Diacerine works by blocking the actions of a certain specific protein that causes swelling, and pain and reduces friction in the joints by the building of cartilage (the soft connective tissue in the bones near the joints) in the joints.
Diaceten ACE 100mg/50mg Tablet may cause common side effects like nausea, vomiting, indigestion, heartburn, stomach pain, diarrhea, loss of appetite, and intense yellow urine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No, Diaceten ACE 100mg/50mg Tablet does not cure Rheumatoid arthritis, but instead, it helps in reducing the pain and inflammation caused by it as it is a pain killer.
No, do not stop taking Diaceten ACE 100mg/50mg Tablet suddenly. If you want to stop taking this medicine, consult your doctor so that he/she might gradually reduce the dose to avoid an unwanted increase in pain or inflammation.
No, Diaceten ACE 100mg/50mg Tablet should ideally not be taken for stomach pain without consulting a physician. This medication can increase the secretion of stomach acid, which may worsen gastritis or an unknown underlying stomach ulcer.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.