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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:06 PM IST
Desirox 500 mg Tablet is used to treat iron overload due to transfusional hemosiderosis (the accumulation of iron in the body due to frequent blood transfusions) or non-transfusion-dependent thalassemia (patients who do not require lifelong regular transfusions for survival). It works by binding to the extra iron and facilitates its removal from the body through faeces. In some cases, this medicine may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, and skin rashes.
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Composition :

DEFERASIROX-500MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Desirox 500 mg Tablet

Desirox 500 mg Tablet is used for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Desirox 500 mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Desirox 500 mg Tablet is available in the form of oral formulations. Please take Desirox 500 mg Tablet in the dose and duration prescribed by your doctor based on specific medical conditions. In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Desirox 500 mg Tablet for as long as your doctor has prescribed it. Do not use Desirox 500 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Desirox 500 mg Tablet if you are pregnant or breastfeeding. Do not use Desirox 500 mg Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Desirox 500 mg Tablet to rule out any side effects.

Uses of Desirox 500 mg Tablet

Used for treating chronic iron overload that occurs due to blood transfusions (transfusional hemosiderosis) in patients two years of age and older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

Medicinal Benefits

Deferasirox is the active component in Desirox 500 mg Tablet . It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

Side Effects of Desirox 500 mg Tablet

  • Diarrhea

  • Vomiting
  • Nausea
  • Abdominal Pain
  • Skin Rashes
  • Increases in Serum Creatinine

Directions for Use

Swallow Desirox 500 mg Tablet whole with water; do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Desirox 500 mg Tablet if you are allergic to Desirox 500 mg Tablet or its ingredients. Desirox 500 mg Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the medicine's benefits outweigh the risks. It is unknown whether Desirox 500 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Desirox 500 mg Tablet as it could lead to unpleasant side effects. Should monitor elderly and paediatric patients closely for toxicity.

Therapeutic Class

CHELATING AGENTS

Drug-Drug Interactions

verifiedApollotooltip
DeferasiroxTheophylline
Severe
DeferasiroxEtidronic acid
Severe

Drug-Food Interactions

verifiedApollotooltip
DEFERASIROX-500MGCaffeine containing foods/drinks
Moderate

Diet & Lifestyle Advise

  • Choose foods high in nutrients, such as fruits, vegetables, and whole grains.

  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.

  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).

  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol and caffeine consumption.

Habit Forming

No

What if I have taken an overdose of Desirox 500 mg Tablet

Take Desirox 500 mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Overdose symptoms may include nausea, abdominal pain, vomiting, diarrhoea, and kidney/liver problems that might be serious. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DES0054

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