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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Defcon 30 mg Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

DEFLAZACORT-30MG

Manufacturer/Marketer :

Saffron Therapeutics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Defcon 30 mg Tablet

Defcon 30 mg Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy.

Defcon 30 mg Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Defcon 30 mg Tablet binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defcon 30 mg Tablet class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defcon 30 mg Tablet makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Defcon 30 mg Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Defcon 30 mg Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defcon 30 mg Tablet can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Defcon 30 mg Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defcon 30 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Defcon 30 mg Tablet , please inform your doctor that you are allergic (hypersensitive) to Defcon 30 mg Tablet . Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Defcon 30 mg Tablet is not safe to use during pregnancy.

Uses of Defcon 30 mg Tablet

Treatment of Duchenne muscular dystrophy (DMD).

Directions for Use

Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

Medicinal Benefits

Defcon 30 mg Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defcon 30 mg Tablet is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

How Defcon 30 mg Tablet Works

Defcon 30 mg Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Defcon 30 mg Tablet binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defcon 30 mg Tablet class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defcon 30 mg Tablet makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Defcon 30 mg Tablet

Most of the side effects of Defcon 30 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

What if I have taken an overdose of Defcon 30 mg Tablet

Do not take more than the prescribed dose of Defcon 30 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defcon 30 mg Tablet .  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defcon 30 mg Tablet . Before taking Defcon 30 mg Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
DeflazacortDexamethasone
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Defcon 30 mg Tablet 10's:
Co-administration of Defcon 30 mg Tablet 10's and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortDexamethasone
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Taking Dexamethasone with Defcon 30 mg Tablet 10's may significantly reduce the blood levels of Defcon 30 mg Tablet 10's, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dexamethasone and Defcon 30 mg Tablet 10's together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortNorfloxacin
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Norfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Defcon 30 mg Tablet 10's.

How to manage the interaction:
Although there is an interaction, Norfloxacin can be taken with Defcon 30 mg Tablet 10's if prescribed by the doctor. However, if you experience pain, or swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without talking to a doctor.
DeflazacortVerapamil
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Coadministration of Verapamil with Defcon 30 mg Tablet 10's can increase the levels of Defcon 30 mg Tablet 10's in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Verapamil with Defcon 30 mg Tablet 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like swelling, weight gain, electrolyte abnormalities, high blood pressure, high blood glucose, muscle weakness, depression, mood swings, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, glaucoma, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortAdalimumab
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Combining Adalimumab with Defcon 30 mg Tablet 10's can increase the risk of severity of side effects.

How to manage the interaction:
Although there is a possibility of interaction between Defcon 30 mg Tablet 10's and Adalimumab, it can be taken if prescribed by a doctor. If you have any symptoms like fever, chills, diarrhea, a sore throat, muscle pain, or experiencing pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortTofacitinib
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Co-administration of Defcon 30 mg Tablet 10's with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Defcon 30 mg Tablet 10's and Tofacitinib, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortSparfloxacin
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Sparfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Defcon 30 mg Tablet 10's.

How to manage the interaction:
Although there is an interaction, Sparfloxacin can be taken with Defcon 30 mg Tablet 10's if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortAspirin
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Using Aspirin together with Defcon 30 mg Tablet 10's may increase the risk of gastric and intestinal ulcers, bleeding and perforation.

How to manage the interaction:
Co-administration of Aspirin with Defcon 30 mg Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. If you have any symptoms unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without consulting a doctor.
DeflazacortFosaprepitant
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Coadministration of Fosaprepitant with Defcon 30 mg Tablet 10's can increase the levels of Defcon 30 mg Tablet 10's in the body.

How to manage the interaction:
Taking Fosaprepitant with Defcon 30 mg Tablet 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortDabrafenib
Severe
How does the drug interact with Defcon 30 mg Tablet 10's:
Co- administration of Dabrafenib with Defcon 30 mg Tablet 10's may significantly reduce the blood levels of Defcon 30 mg Tablet 10's, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dabrafenib and Defcon 30 mg Tablet 10's together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-30MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-30MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Defcon 30 mg Tablet 10's therapy may elevate Defcon 30 mg Tablet 10's levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Defcon 30 mg Tablet Substitute

Substitutes safety advice
  • Defcort 30 Tablet 6's

    by Others

    63.00per tablet
  • Defza 30 Tablet 6's

    by Others

    55.65per tablet
  • Defort-30 Tablet 10's

    by Others

    38.61per tablet
  • Kivicort-30 Tablet 6's

    by Others

    33.38per tablet
  • Lifecort 30 mg Tablet 10's

    by AYUR

    53.46per tablet
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Alcohol

Caution

The effect of taking both alcohol and Defcon 30 mg Tablet may lead to bleeding & ulcers in the stomach. Doctors' consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Defcon 30 mg Tablet crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Defcon 30 mg Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Defcon 30 mg Tablet .

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Kidney

Caution

Before using Defcon 30 mg Tablet by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Defcon 30 mg Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Defcon 30 mg Tablet .

FAQs

Defcon 30 mg Tablet is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.
Not recommended in mild allergies. Defcon 30 mg Tablet is recommended only on consulting a doctor as Defcon 30 mg Tablet is a strong medicine that produces considerable side effects & thus used only in moderate to severe cases.
It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.
It is not recommended to be taken Defcon 30 mg Tablet with alcohol as it may cause stomach bleeding.
No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Defcon 30 mg Tablet may be used in extreme cases of seasonal allergy.
You should not use Defcon 30 mg Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Defcon 30 mg Tablet if you have a compromised immune system, eye problems or weak bones.
Yes, Defcon 30 mg Tablet is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.
Defcon 30 mg Tablet is less potent than Prednisone and is usually administered proportionately in higher doses.
No, Defcon 30 mg Tablet is not a painkiller. It is a steroid medication.
Yes, it can be used to treat kidney stones.
Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Yes, it is safe to use Defcon 30 mg Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Common side effects of Defcon 30 mg Tablet may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defcon 30 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

Country of origin

India

Manufacturer/Marketer address

SCF- 3,Sector- 2,Sector 1,Panchkula-134109, Haryana, India
Other Info - DEF0165

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