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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cortrik 30 mg Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DEFLAZACORT-30MG

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cortrik 30 mg Tablet

Cortrik 30 mg Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy.

Cortrik 30 mg Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Cortrik 30 mg Tablet binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Cortrik 30 mg Tablet class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Cortrik 30 mg Tablet makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Cortrik 30 mg Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Cortrik 30 mg Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Cortrik 30 mg Tablet can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Cortrik 30 mg Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Cortrik 30 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Cortrik 30 mg Tablet , please inform your doctor that you are allergic (hypersensitive) to Cortrik 30 mg Tablet . Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Cortrik 30 mg Tablet is not safe to use during pregnancy.

Uses of Cortrik 30 mg Tablet

Treatment of Duchenne muscular dystrophy (DMD).

Directions for Use

Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

Medicinal Benefits

Cortrik 30 mg Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Cortrik 30 mg Tablet is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

How Cortrik 30 mg Tablet Works

Cortrik 30 mg Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Cortrik 30 mg Tablet binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Cortrik 30 mg Tablet class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Cortrik 30 mg Tablet makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cortrik 30 mg Tablet

Most of the side effects of Cortrik 30 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

What if I have taken an overdose of Cortrik 30 mg Tablet

Do not take more than the prescribed dose of Cortrik 30 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Cortrik 30 mg Tablet .  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Cortrik 30 mg Tablet . Before taking Cortrik 30 mg Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
DeflazacortThalidomide
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Cortrik 30 mg Tablet 10's:
Co-administration of Cortrik 30 mg Tablet 10's and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortThalidomide
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Taking thalidomide together with Cortrik 30 mg Tablet 10's may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Cortrik 30 mg Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
DeflazacortImatinib
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Co-administration of Imatinib with Cortrik 30 mg Tablet 10's can increase the levels of Cortrik 30 mg Tablet 10's in the body.

How to manage the interaction:
Taking Imatinib with Cortrik 30 mg Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, breathing problems, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortBosentan
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Taking Bosentan with Cortrik 30 mg Tablet 10's may significantly reduce the blood levels of Cortrik 30 mg Tablet 10's, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Cortrik 30 mg Tablet 10's together can result in an interaction, they can be taken together if advised by your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortFosamprenavir
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Coadministration of Fosamprenavir with Cortrik 30 mg Tablet 10's can increase the levels of Cortrik 30 mg Tablet 10's in the body.

How to manage the interaction:
Taking Cortrik 30 mg Tablet 10's with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, mood swings, excessive growth of facial or body hair, sudden dizziness, lightheadedness, or shortness of breath, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortGatifloxacin
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Gatifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Cortrik 30 mg Tablet 10's.

How to manage the interaction:
Although there is an interaction, Gatifloxacin can be taken with Cortrik 30 mg Tablet 10's if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortClarithromycin
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Co-administration of Clarithromycin with Cortrik 30 mg Tablet 10's can increase the levels of Cortrik 30 mg Tablet 10's in the body.

How to manage the interaction:
Taking Clarithromycin with Cortrik 30 mg Tablet 10's together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, or fainting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortDeferasirox
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Using Deferasirox together with Cortrik 30 mg Tablet 10's may increase the risk of gastric and intestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Deferasirox with Cortrik 30 mg Tablet 10's can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like stomach pain, dizziness, loss of appetite, nausea, vomiting, or black or tarry stools, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
DeflazacortSparfloxacin
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Sparfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Cortrik 30 mg Tablet 10's.

How to manage the interaction:
Although there is an interaction, Sparfloxacin can be taken with Cortrik 30 mg Tablet 10's if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortOfloxacin
Severe
How does the drug interact with Cortrik 30 mg Tablet 10's:
Co-administration Bempedoic acid and Cortrik 30 mg Tablet 10's can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Although taking Bempedoic acid and Cortrik 30 mg Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-30MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-30MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Cortrik 30 mg Tablet 10's therapy may elevate Cortrik 30 mg Tablet 10's levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Cortrik 30 mg Tablet Substitute

Substitutes safety advice
  • Defcort 30 Tablet 6's

    63.00per tablet
  • Defza 30 Tablet 6's

    55.65per tablet
  • Defort-30 Tablet 10's

    38.61per tablet
  • Kivicort-30 Tablet 6's

    33.38per tablet
  • Lifecort 30 mg Tablet 10's

    by AYUR

    53.46per tablet
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Alcohol

Caution

The effect of taking both alcohol and Cortrik 30 mg Tablet may lead to bleeding & ulcers in the stomach. Doctors' consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Cortrik 30 mg Tablet crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Cortrik 30 mg Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Cortrik 30 mg Tablet .

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Kidney

Caution

Before using Cortrik 30 mg Tablet by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Cortrik 30 mg Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Cortrik 30 mg Tablet .

FAQs

Cortrik 30 mg Tablet is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.
Not recommended in mild allergies. Cortrik 30 mg Tablet is recommended only on consulting a doctor as Cortrik 30 mg Tablet is a strong medicine that produces considerable side effects & thus used only in moderate to severe cases.
It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.
It is not recommended to be taken Cortrik 30 mg Tablet with alcohol as it may cause stomach bleeding.
No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Cortrik 30 mg Tablet may be used in extreme cases of seasonal allergy.
You should not use Cortrik 30 mg Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Cortrik 30 mg Tablet if you have a compromised immune system, eye problems or weak bones.
Yes, Cortrik 30 mg Tablet is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.
Cortrik 30 mg Tablet is less potent than Prednisone and is usually administered proportionately in higher doses.
No, Cortrik 30 mg Tablet is not a painkiller. It is a steroid medication.
Yes, it can be used to treat kidney stones.
Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Yes, it is safe to use Cortrik 30 mg Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Common side effects of Cortrik 30 mg Tablet may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Cortrik 30 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

Country of origin

INDIA

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Other Info - COR0387

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