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Composition

DECITABINE-30MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Decitex 30 Inj

Decitex 30 Inj belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. A myelodysplastic syndrome is a group of malignancies known as myelodysplastic syndromes that occur when immature blood cells in the bone marrow do not mature or turn into healthy blood cells.

Decitex 30 Inj contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow.

Decitabine should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer chemotherapeutic agents. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides you will benefit from additional treatment. The most common adverse reactions of Decitex 30 Inj are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Talk with your doctor if you experience any of these side effects persistently.

Decitabine may harm your fetus. Avoid taking Decitex 30 Inj if you are pregnant or breastfeeding. You or your partner should not become pregnant while you are using decitabine. It would be best if you used birth control to prevent pregnancy in yourself or your partner during your treatment with decitabine and for two months afterwards. Call your doctor if you or your partner becomes pregnant while using decitabine. If you are breastfeeding. Do not breastfeed while you take this drug and for two weeks after your last dose. Decitex 30 Inj may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if alert. Decitex 30 Inj is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about your health condition and medications before taking Decitex 30 Inj to rule out interactions.

Uses of Decitex 30 Inj

Treatment of Myelodysplastic syndrome

Medicinal Benefits

Decitex 30 Inj belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. Decitex 30 Inj contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. On the other hand, it can treat blood cancer, known as acute myeloid leukemia (AML).

Side Effects of Decitex 30 Inj

  • Injection site reactions
  • Excessive tiredness or weakness
  • Headache
  • Dizziness or confusion
  • Fast heartbeat
  • Difficulty falling asleep or staying asleep
  • Shortness of breath
  • Nausea
  • Stomach pain
  • Diarrhoea
  • Vomiting
  • Painful sores in the mouth, or on the tongue or lips
  • Rash
  • Neutropenia (low white blood cells)
  • Thrombocytopenia (low platelets)
  • Change in skin colour or pale skin or red spots on the skin
  • Hair loss
  • Joint or muscle pain
  • Heartburn or indigestion
  • Chest discomfort or chest wall pain
  • Swelling of the hands, feet, ankles, lower legs, or stomach

Directions for Use

Decitex 30 Inj should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Decitex 30 Inj, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may have a higher risk of infection. Hands must be washed frequently. Avoid contact with those who have illnesses, colds, or the flu. You may bleed more easily. Take precautions to avoid injury. Do not skip any scheduled dose or take other medications unless prescribed by the doctor.

Therapeutic Class

MISCELLANEOUS

Drug Interactions

Drug-Drug Interactions: Decitex 30 Inj may interact with medicines used to treat rheumatoid and psoriatic arthritis (e.g. adalimumab, baricitinib, leflunomide), vaccinations (e.g. BCG vaccine, dengue vaccine, yellow fever vaccine), antipsychotic medication (e.g. clozapine).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Decitex 30 Inj may interact with various disease conditions, including liver, kidney and haematological toxicities (Low platelet level,  low count of a type of white blood cell).

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • LEFLUNOMIDE
  • BCG VACCINE
  • DENGUE VACCINE
  • YELLOW FEVER VACCINE
  • CLOZAPINE

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

What if I have taken an overdose of Decitex 30 Inj

Since Decitex 30 Inj is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Decitex 30 Inj may cause unusual bleeding or bruising, sore throat, fever, chills, cough, or other signs of infection.

Special Advise

  • Regular blood tests are advised before and during treatment with Decitex 30 Inj.

Disease/Condition Glossary

Myelodysplastic syndromes: Myelodysplastic syndromes are malignancies in which immature blood cells in the bone marrow do not mature and do not become healthy blood cells. Abnormalities in blood cells and bone marrow distinguish the many forms of myelodysplastic syndromes.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Decitex 30 Inj as it might cause increased dizziness.

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Pregnancy

Unsafe

Decitex 30 Inj should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Decitex 30 Inj should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Unsafe

Decitex 30 Inj may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Inform your doctor before receiving the Decitex 30 Inj if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Decitex 30 Inj if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Decitex 30 Inj is not recommended for children below 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - DEC0201

Author Details

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FAQs

Decitex 30 Inj is used to treat Myelodysplastic syndrome.
Decitex 30 Inj contains Decitabine, which works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.
Decitabine therapy should usually be given as a three- or five-day regimen based on your medical condition and response to the treatment. Do not stop taking Decitex 30 Inj on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Decitex 30 Inj.
Decitex 30 Inj can be used to treat blood cancer known as acute myeloid leukemia (AML).
Decitex 30 Inj therapy may cause a change in skin colour or pale skin or red spots on the skin. Consult your doctor immediately if you notice these symptoms persistently.
Decitex 30 Inj might cause neutropenia (low white blood cells) and thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Decitex 30 Inj.
Decitabine may raise blood sugar. If you have high blood sugar (diabetes), talk with your doctor.

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