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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Decitas 30 mg Injection 1's used to treat myelodysplastic syndrome. It contains Decitabine, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. The most common adverse reactions of Decitas 30 mg Injection 1's are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach.

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Composition

DECITABINE-30MG

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Decitas 30 mg Injection 1's

Decitas 30 mg Injection 1's belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. A myelodysplastic syndrome is a group of malignancies known as myelodysplastic syndromes that occur when immature blood cells in the bone marrow do not mature or turn into healthy blood cells.

Decitas 30 mg Injection 1's contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow.

Decitabine should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer chemotherapeutic agents. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides you will benefit from additional treatment. The most common adverse reactions of Decitas 30 mg Injection 1's are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Talk with your doctor if you experience any of these side effects persistently.

Decitabine may harm your fetus. Avoid taking Decitas 30 mg Injection 1's if you are pregnant or breastfeeding. You or your partner should not become pregnant while you are using decitabine. It would be best if you used birth control to prevent pregnancy in yourself or your partner during your treatment with decitabine and for two months afterwards. Call your doctor if you or your partner becomes pregnant while using decitabine. If you are breastfeeding. Do not breastfeed while you take this drug and for two weeks after your last dose. Decitas 30 mg Injection 1's may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if alert. Decitas 30 mg Injection 1's is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about your health condition and medications before taking Decitas 30 mg Injection 1's to rule out interactions.

Uses of Decitas 30 mg Injection 1's

Treatment of Myelodysplastic syndrome

Medicinal Benefits

Decitas 30 mg Injection 1's belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. Decitas 30 mg Injection 1's contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. On the other hand, it can treat blood cancer, known as acute myeloid leukemia (AML).

Directions for Use

Decitas 30 mg Injection 1's should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Decitas 30 mg Injection 1's

  • Injection site reactions
  • Excessive tiredness or weakness
  • Headache
  • Dizziness or confusion
  • Fast heartbeat
  • Difficulty falling asleep or staying asleep
  • Shortness of breath
  • Nausea
  • Stomach pain
  • Diarrhoea
  • Vomiting
  • Painful sores in the mouth, or on the tongue or lips
  • Rash
  • Neutropenia (low white blood cells)
  • Thrombocytopenia (low platelets)
  • Change in skin colour or pale skin or red spots on the skin
  • Hair loss
  • Joint or muscle pain
  • Heartburn or indigestion
  • Chest discomfort or chest wall pain
  • Swelling of the hands, feet, ankles, lower legs, or stomach

Drug Warnings

Before taking the Decitas 30 mg Injection 1's, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may have a higher risk of infection. Hands must be washed frequently. Avoid contact with those who have illnesses, colds, or the flu. You may bleed more easily. Take precautions to avoid injury. Do not skip any scheduled dose or take other medications unless prescribed by the doctor.

Drug Interactions

Drug-Drug Interactions: Decitas 30 mg Injection 1's may interact with medicines used to treat rheumatoid and psoriatic arthritis (e.g. adalimumab, baricitinib, leflunomide), vaccinations (e.g. BCG vaccine, dengue vaccine, yellow fever vaccine), antipsychotic medication (e.g. clozapine).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Decitas 30 mg Injection 1's may interact with various disease conditions, including liver, kidney and haematological toxicities (Low platelet level,  low count of a type of white blood cell).

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • LEFLUNOMIDE
  • BCG VACCINE
  • DENGUE VACCINE
  • YELLOW FEVER VACCINE
  • CLOZAPINE

Habit Forming

No

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Regular blood tests are advised before and during treatment with Decitas 30 mg Injection 1's.

Disease/Condition Glossary

Myelodysplastic syndromes: Myelodysplastic syndromes are malignancies in which immature blood cells in the bone marrow do not mature and do not become healthy blood cells. Abnormalities in blood cells and bone marrow distinguish the many forms of myelodysplastic syndromes.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Decitas 30 mg Injection 1's as it might cause increased dizziness.

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Pregnancy

Unsafe

Decitas 30 mg Injection 1's should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Decitas 30 mg Injection 1's should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Unsafe

Decitas 30 mg Injection 1's may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Inform your doctor before receiving the Decitas 30 mg Injection 1's if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Decitas 30 mg Injection 1's if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Decitas 30 mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DEC0208

Author Details

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FAQs

Decitas 30 mg Injection 1's is used to treat Myelodysplastic syndrome.
Decitas 30 mg Injection 1's contains Decitabine, which works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.
Decitabine therapy should usually be given as a three- or five-day regimen based on your medical condition and response to the treatment. Do not stop taking Decitas 30 mg Injection 1's on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Decitas 30 mg Injection 1's.
Decitas 30 mg Injection 1's can be used to treat blood cancer known as acute myeloid leukemia (AML).
Decitas 30 mg Injection 1's therapy may cause a change in skin colour or pale skin or red spots on the skin. Consult your doctor immediately if you notice these symptoms persistently.
Decitas 30 mg Injection 1's might cause neutropenia (low white blood cells) and thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Decitas 30 mg Injection 1's.
Decitabine may raise blood sugar. If you have high blood sugar (diabetes), talk with your doctor.
No, Decitas 30 mg Injection 1's is not a vesicant. It is an anti-cancer drug that is not known to cause severe tissue damage when it leaks from the injection site into surrounding tissues. It belongs to the group of medications called hypo methylation agents used to treat myelodysplastic syndrome.
Decitas 30 mg Injection 1's effectively treats myelodysplastic syndrome, a group of disorders in which the bone marrow produces misshapen blood cells and insufficient healthy blood cells. It works by promoting the production of normal blood cells in the bone marrow and eliminating abnormal cells. However, the degree of effectiveness varies among individuals based on their medical condition.
Yes, Decitas 30 mg Injection 1's may cause hair loss as a common side effect. To cope with hair loss, manage stress, maintain a healthy diet, avoid harsh hair treatments, use gentle hair care products, and consider medical treatments or therapies as advised by a doctor.
Decitas 30 mg Injection 1's is administered through an intravenous route (into a vein) slowly over 3 hours by the doctor or nurse. It is usually administered every 8 hours for 3 days depending on the prescribed dose and treatment plan.
The side effects of Decitas 30 mg Injection 1's include vomiting, nausea, injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, constipation, diarrhoea, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Consult the doctor if any of these side effects persist or worsen.

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