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Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:35 AM IST

Dacarb 500 mg Injection is used to treat skin cancer. It contains Dacarbazine, an alkylating agent that inhibits the DNA and RNA transcription essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells. Dacarb 500 mg Injection may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the injection site.

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Prescription drug

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Composition :

DACARBAZINE-500MG

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dacarb 500 mg Injection

Dacarb 500 mg Injection is a chemotherapeutic medicine used in the treatment of skin cancer. Cancer is a condition where the cells grow and reproduce uncontrollably in a specific body part. These cancerous cells can attack and destroy surrounding healthy tissue and organs. Dacarb 500 mg Injection is used in the treatment of metastatic malignant melanoma. It is a serious condition in which the cancer grows in melanocytes and also spreads to other parts of the body. Dacarb 500 mg Injection is also used as a second-line therapy in the treatment of Hodgkin’s Disease when used in combination with other approved drugs.

Dacarb 500 mg Injection contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Dacarb 500 mg Injection may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dacarb 500 mg Injection is a parenteral preparation. A trained healthcare professional will administer it. 

Dacarb 500 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including medications you take, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or heart problems. Dacarb 500 mg Injection may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring of blood and liver functioning should be done during the entire treatment. This medicine is known to cause fetal harm if used in pregnancy. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding before taking Dacarb 500 mg Injection.

Uses of Dacarb 500 mg Injection

Treatment of Metastatic Malignant Melanoma and Hodgkin's Disease

Medicinal Benefits

Dacarb 500 mg Injection contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Side Effects of Dacarb 500 mg Injection

  • Nausea
  • Dizziness
  • Fever
  • Chills
  • Sore throat
  • Headache
  • Vomiting
  • Cough
  • Decreased platelet count
  • Bruising or bleeding gums
  • Pain at the site of injection

Directions for Use

Dacarb 500 mg Injection will be administered by a trained healthcare professional. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Dacarb 500 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or cardiac disorders. Dacarb 500 mg Injection may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women and breastfeeding mothers. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. It is unknown whether Dacarb 500 mg Injection can be administered to children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

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DacarbazineCladribine
Severe
DacarbazineClozapine
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid going out in the hot sun, as it can harm your skin.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

How Dacarb 500 mg Injection Works

Dacarb 500 mg Injection contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

What if I have taken an overdose of Dacarb 500 mg Injection

Since Dacarb 500 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Dacarb 500 mg Injection to prevent serious side effects.

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Pregnancy

Unsafe

Dacarb 500 mg Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Dacarb 500 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Dacarb 500 mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Caution

Dacarb 500 mg Injection will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Dacarb 500 mg Injection. It may cause hepatic necrosis when administered with other antineoplastics. Hence, Dacarb 500 mg Injection should be used with caution in patients with liver problems. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Dacarb 500 mg Injection. It should be used with caution in patients with renal impairment. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Consult your doctor

Limited information is available for the use of Dacarb 500 mg Injection in children. It will be administered to the children only if clearly needed. If administered, careful monitoring of the child is needed.

Country of origin

INDIA

Manufacturer/Marketer address

305, Bakshi House, 40-41, Nehru Place ., New Delhi- 110 017
Other Info - DAC0061

Author Details

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FAQs

Dacarb 500 mg Injection is used to treat Metastatic Malignant Melanoma and Hodgkin’s Disease.
Dacarb 500 mg Injection contains Dacarbazine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.
Dacarb 500 mg Injection may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.
Dacarb 500 mg Injection is administered intravenously by a trained healthcare professional. Hence, do not self-administer.
Dacarb 500 mg Injection is not a potent vesicant. Dacarb 500 mg Injection is a chemotherapeutic medicine used in the treatment of skin cancer.
Dacarb 500 mg Injection works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.
Dacarb 500 mg Injection may cause hair loss. Tell your doctor if it is severe or does not go away.
The common side effects of Dacarb 500 mg Injection may include nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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Keep Refrigerated. Do not freeze.

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