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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dabirex-110 Capsule is used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It contains Dabigatran, which works by inhibiting the production of clotting factors and prevents blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. It may cause side effects such as bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DABIGATRAN-110MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Dabirex-110 Capsule

Dabirex-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Dabirex-110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Dabirex-110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Take Dabirex-110 Capsule as prescribed by your doctor. You are advised to take Dabirex-110 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), and nausea, stomach pain, indigestion. Most of these side effects of Dabirex-110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Dabirex-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabirex-110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabirex-110 Capsule . Try not to stop taking this medicine of your own. Stopping a sudden intake of Dabirex-110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke.

Uses of Dabirex-110 Capsule

Prevention of stroke, Prevention of heart attack.

Directions for Use

Swallow Dabirex-110 Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Dabirex-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinner. It prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm). Dabirex-110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dabirex-110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Dabirex-110 Capsule Works

Dabirex-110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Dabirex-110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dabirex-110 Capsule

  • Stomach pain
  • Indigestion
  • Bleeding
  • Anemia (low number of red blood cells)
  • Nausea
  • Diarrhea

What if I have taken an overdose of Dabirex-110 Capsule

Do not take more than the prescribed dose of Dabirex-110 Capsule as it may cause overdose leading to excessive bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Dabirex-110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabirex-110 Capsule . Safety and effectiveness of Dabirex-110 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabirex-110 Capsule . Try not to stop taking Dabirex-110 Capsule of your own. Stopping a sudden intake of Dabirex-110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Dabirex-110 Capsule . You should inform the doctor that you are taking Dabirex-110 Capsule before any surgery is scheduled. Dabirex-110 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Avoid consumption of alcohol while taking Dabirex-110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateFenoprofen
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Dabirex-110 Capsule 10's:
When Mifepristone is taken with Dabirex-110 Capsule 10's, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabirex-110 Capsule 10's is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateFenoprofen
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Taking Dabirex-110 Capsule 10's with Fenoprofen can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule 10's with Fenoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateClopidogrel
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Taking Clopidogrel with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between clopidogrel and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
Dabigatran etexilatePrasugrel
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Taking Dabirex-110 Capsule 10's with Prasugrel can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although taking Prasugrel and Dabirex-110 Capsule 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateRivaroxaban
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Co-administration of Dabirex-110 Capsule 10's and Rivaroxaban can increase the risk of bleeding, including severe blood loss.

How to manage the interaction:
Co-administration of Dabirex-110 Capsule 10's and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding, dizziness, tarry stools, coughing up or vomiting blood, or severe headache, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateRamucirumab
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Taking Dabirex-110 Capsule 10's with Ramucirumab can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule 10's with Ramucirumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateTiclopidine
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Taking Dabirex-110 Capsule 10's with Ticlopidine can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule 10's with Ticlopidine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateSulindac
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Combining Sulindac with Dabirex-110 Capsule 10's can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Dabirex-110 Capsule 10's with Sulindac together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateTolmetin
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Taking Dabirex-110 Capsule 10's with Tolmetin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabirex-110 Capsule 10's with Tolmetin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDiclofenac
Severe
How does the drug interact with Dabirex-110 Capsule 10's:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabirex-110 Capsule 10's. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabirex-110 Capsule 10's treatment.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Dabirex-110 Capsule .

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Dabirex-110 Capsule Substitute

Substitutes safety advice
  • Dabigo 110 mg Capsule 10's

    by AYUR

    14.58per tablet
  • Afogatran 110 Capsule 10's

    by AYUR

    32.04per tablet
  • Dabistar 110 Capsule 10's

    by AYUR

    31.55per tablet
  • Dablexa 110 Capsule 10's

    by AYUR

    32.04per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dabirex-110 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Dabirex-110 Capsule is unsafe to use during pregnancy since it affects the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabirex-110 Capsule .

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Breast Feeding

Caution

There is limited data on how Dabirex-110 Capsule affects breastfeeding. However, it is unsafe to use Dabirex-110 Capsule if you are lactating, since it passes through the breast milk and harm the baby. Please consult your doctor before starting Dabirex-110 Capsule .

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Driving

Caution

Dabirex-110 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabirex-110 Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Dabirex-110 Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Dabirex-110 Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Dabirex-110 Capsule have not been established in children.

FAQs

Dabirex-110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation.
Please consult your doctor if Dabirex-110 Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Dabirex-110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery. It also causes a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural). This type of blood clot could cause long-term paralysis.
Dabirex-110 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. It is advisable, please consult your doctor and take Dabirex-110 Capsule for as long as your doctor has prescribed it.
Taking Dabirex-110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabirex-110 Capsule .
Dabirex-110 Capsule consists of Dabigatran is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.
No, you are not recommended to stop taking Dabirex-110 Capsule without consulting your doctor to worsen the condition. Therefore, take Dabirex-110 Capsule for as long as your doctor has prescribed it.
Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.
You can take Dabirex-110 Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.
Take Dabirex-110 Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Dabirex-110 Capsule as long as your doctor has prescribed it for you.
You are recommended to avoid consumption of alcohol with Dabirex-110 Capsule as it may increase the risk of bleeding.
Hair loss is not a known side effect of Dabirex-110 Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.
It varies from person to person and depends on the conditions that we treat.
Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabirex-110 Capsule . However, it is not recommended in patients with severe liver diseases.
Store in a cool and dry place away from sunlight. Keep Dabirex-110 Capsule out of the sight and reach of children.
Yes, bleeding is the main risk associated with Dabirex-110 Capsule treatment; patients should be monitored for signs of bleeding.
Dabirex-110 Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Dabirex-110 Capsule .
Common side effects of Dabirex-110 Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - DAB0406

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