Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Afogatran 110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Afogatran 110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Take Afogatran 110 Capsule as prescribed by your doctor. You are advised to take Afogatran 110 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), and nausea, stomach pain, indigestion. Most of these side effects of Afogatran 110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule . Try not to stop taking this medicine of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke.

Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinner. It prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm). Afogatran 110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Afogatran 110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

• Stomach pain
• Indigestion
• Bleeding
• Anemia (low number of red blood cells)
• Nausea
• Diarrhea

If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . Safety and effectiveness of Afogatran 110 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule . Try not to stop taking Afogatran 110 Capsule of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Afogatran 110 Capsule . You should inform the doctor that you are taking Afogatran 110 Capsule before any surgery is scheduled. Afogatran 110 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Avoid consumption of alcohol while taking Afogatran 110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions: Afogatran 110 Capsule may interact with medicines to reduce blood clotting (warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban), medicines to treat abnormal heartbeats  (amiodarone, dronedarone, quinidine, verapamil), medicines to treat fungal infections (ketoconazole, itraconazole), medicines to prevent organ rejection after transplantation (tacrolimus, cyclosporine) antiviral or HIV medicines (lopinavir, ritonavir, glecaprevir, pibrentasvir), antibiotics (rifampicin or clarithromycin), pain reliever (aspirin, ibuprofen, diclofenac), antiepileptic drugs (carbamazepine, phenytoin).

Drug-Food Interactions: Afogatran 110 Capsule may interact with St. John’s wort, herbal medicine for depression.

Drug-Disease Interactions: Use with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

• WARFARIN
• PHENPROCOUMON
• ACENOCOUMAROL
• HEPARIN
• CLOPIDOGREL
• PRASUGREL
• TICAGRELOR
• RIVAROXABAN
• AMIODARONE
• DRONEDARONE
• QUINIDINE
• VERAMAPIL
• KETOCONAZOLE
• ITRACONAZOLE
• TACROLIMUS
• CYCLOSPORINE
• LOPINAVIR
• RITONAVIR
• GLECAPREVIR
• PIBRENTASVIR
• RIFAMPICIN
• CLARITHROMYCIN
• ASPIRIN
• IBUPROFEN
• DICLOFENAC
• CARBAMAZEPINE
• PHENYTOIN

• Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Afogatran 110 Capsule .

• Keep your cholesterol and triglyceride levels under control.

• Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

• Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

• Keep a check on your weight and exercise regularly to keep your heart healthy.

• Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio to analyze your blood clotting time.

A blood clot can occur in any part of the body that can lead to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat build upon the walls of the arteries) can cause a blood clot in your limbs.