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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:18 PM IST

Cytrosar 1000mg Injection is an anticancer medicine used to treat leukemia (blood cancer). It contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in cancer cells, which is essential for cell growth, repair, and multiplication. Thus, It stops the multiplication of abnormal cells, leads to the development of cells in an unbalanced way and causes the death of cells.

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Manufacturer/Marketer

Vhb Life Sciences Inc

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Cytrosar 1000mg Injection

Cytrosar 1000mg Injection is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Cytrosar 1000mg Injection is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

Cytrosar 1000mg Injection contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Cytrosar 1000mg Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Cytrosar 1000mg Injection may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of Cytrosar 1000mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Cytrosar 1000mg Injection. Hence, do not self-administer.

If you are allergic to Cytrosar 1000mg Injection, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Cytrosar 1000mg Injection. Cytrosar 1000mg Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with Cytrosar 1000mg Injection as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Cytrosar 1000mg Injection may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of Cytrosar 1000mg Injection

Treatment of Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia

Medicinal Benefits

Cytrosar 1000mg Injection contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, Cytrosar 1000mg Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Directions for Use

Your oncology doctor will administer Cytrosar 1000mg Injection. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cytrosar 1000mg Injection

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dark-coloured urine
  • Dizziness
  • Confusion
  • Stomach pain
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

Cytrosar 1000mg Injection should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Cytrosar 1000mg Injection. Cytrosar 1000mg Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking Cytrosar 1000mg Injection if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with Cytrosar 1000mg Injection as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Cytrosar 1000mg Injection may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Cytrosar 1000mg Injection as it may cause infection.

Drug Interactions

Drug-Drug Interactions: Cytrosar 1000mg Injection may interact with medicines used to treat ulcerative colitis (mesalazine, olsalazine), anti-inflammatory drugs (sulfasalazine), aminoglycosides (gentamicin, amikacin, neomycin), cardiac glycoside, cholera vaccine, typhoid vaccine.

Drug-Food Interactions: Cytrosar 1000mg Injection may interact with alcohol. Therefore, avoid alcohol consumption with Cytrosar 1000mg Injection as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with Cytrosar 1000mg Injection.

Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Cytrosar 1000mg Injection as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Special Advise

  • Regular blood tests are recommended while taking Cytrosar 1000mg Injection to monitor the number and type of cells in the blood. 
  • Cytrosar 1000mg Injection, like other cytotoxic medicines, can cause hyperuricemia due to the fast lysis of neoplastic cells. Blood uric acid levels should be monitored and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.

Disease/Condition Glossary

Chronic myeloid leukemia: It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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Alcohol

Unsafe

Avoid consumption of alcohol with Cytrosar 1000mg Injection as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Cytrosar 1000mg Injection. You should not become pregnant while on treatment with Cytrosar 1000mg Injection.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Cytrosar 1000mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Cytrosar 1000mg Injection causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Cytrosar 1000mg Injection.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Cytrosar 1000mg Injection. It may lead to CNS toxicity in high doses.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Cytrosar 1000mg Injection as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Cytrosar 1000mg Injection, combined with other approved anti-cancer medications, is suggested for inducing remission in adults and children with acute non-lymphocytic leukemia. Consult your doctor for more information.

Country of origin

India
Other Info - CY74988

FAQs

Cytrosar 1000mg Injection is used to treat Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.
Cytrosar 1000mg Injection contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Cytrosar 1000mg Injection as it may cause infections.
Cytrosar 1000mg Injection may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Cytrosar 1000mg Injection if you are planning to become pregnant.
Cytrosar 1000mg Injection contains cytarabine as its active component. It is an anticancer medicine which belongs to the class of anti-metabolites.
Cytrosar 1000mg Injection is not considered a vesicant (irritant), but it should be administered carefully to prevent any potential issues.
No, ototoxicity (hearing damage) has not been reported with Cytrosar 1000mg Injection use. However, if you experience any related symptoms, it is important to consult your doctor.
Yes, Cytrosar 1000mg Injection is a cytotoxic (cell-damaging).
Yes, Cytrosar 1000mg Injection may cause hair loss as this is one of its side effects. However, please, consult a doctor if this persists for longer durations.
Cytrosar 1000mg Injection causes side effects such as nausea, vomiting, mouth ulcers, loss of appetite, diarrhoea, dark-coloured urine, confusion, dizziness, stomach pain, weakness, and injection site reactions. These will gradually reduce over time. However, consult a doctor if any of these persists longer.

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