Biobin 1gm Injection is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Biobin 1gm Injection is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

Biobin 1gm Injection contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Biobin 1gm Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Biobin 1gm Injection may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of Biobin 1gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Biobin 1gm Injection. Hence, do not self-administer.

If you are allergic to Biobin 1gm Injection, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Biobin 1gm Injection. Biobin 1gm Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with Biobin 1gm Injection as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Biobin 1gm Injection may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Biobin 1gm Injection contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, Biobin 1gm Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

• Vomiting
• Nausea
• Mouth ulcers
• Loss of appetite
• Diarrhoea
• Dark-coloured urine
• Dizziness
• Confusion
• Stomach pain
• Weakness
• Injection site reactions
• Pain at the site of injection

Biobin 1gm Injection should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Biobin 1gm Injection. Biobin 1gm Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking Biobin 1gm Injection if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with Biobin 1gm Injection as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Biobin 1gm Injection may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Biobin 1gm Injection as it may cause infection.

Drug-Drug Interactions: Biobin 1gm Injection may interact with medicines used to treat ulcerative colitis (mesalazine, olsalazine), anti-inflammatory drugs (sulfasalazine), aminoglycosides (gentamicin, amikacin, neomycin), cardiac glycoside, cholera vaccine, typhoid vaccine.

Drug-Food Interactions: Biobin 1gm Injection may interact with alcohol. Therefore, avoid alcohol consumption with Biobin 1gm Injection as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with Biobin 1gm Injection.

• MESALAZINE
• OLSALAZINE
• SULFASALAZINE
• GENTAMICIN
• AMIKACIN
• CHOLERA VACCINE
• TYPHOID VACCINE

• Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
• Drink plenty of water daily while taking Biobin 1gm Injection as some cancer therapies may cause dehydration.
• Exercise regularly and maintain a healthy body weight.
• Regularly wash your hands and avoid contact with people having infections.
• Quit smoking.

• Regular blood tests are recommended while taking Biobin 1gm Injection to monitor the number and type of cells in the blood. 
• Biobin 1gm Injection, like other cytotoxic medicines, can cause hyperuricemia due to the fast lysis of neoplastic cells. Blood uric acid levels should be monitored and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.

Chronic myeloid leukemia: It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.