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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cresemba 200Mg Injection is used to treat fungal infections. It contains Isavuconazole, which works by fungicidal actions by disrupting the biosynthesis of ergosterol, which is essential for their survival and kills the fungus that causes infection. Common side effects of Cresemba 200Mg Injection are headache, decreased appetite, sleepiness, nausea, vomiting, stomach pain, diarrhoea or chest pain.
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Whats That

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Composition :

ISAVUCONAZOLE-200MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cresemba 200Mg Injection

Cresemba 200Mg Injection belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis (in patients for whom Amphotericin B is not suitable). Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs by breathing and spreads from the lungs to the kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

Cresemba 200Mg Injection contains Isavuconazole which works by fungicidal actions by disrupting the biosynthesis of ergosterol,which are essential for their survival and kills fungus that causes infection.

Cresemba 200Mg Injection will be administered by a healthcare professional; do not self-administer. Some people may experience headache, decreased appetite, sleepiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Cresemba 200Mg Injection do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Cresemba 200Mg Injection or any other medicines, please tell your doctor. Cresemba 200Mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Cresemba 200Mg Injection. Avoid breastfeeding while taking Cresemba 200Mg Injection. Drive only if you are alert after taking Cresemba 200Mg Injection as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Cresemba 200Mg Injection as it may increase the risk of liver damage.

Uses of Cresemba 200Mg Injection

Treatment of Invasive aspergillosis and Mucormycosis

Directions for Use

Cresemba 200Mg Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Cresemba 200Mg Injection contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Cresemba 200Mg Injection kills or stops the growth of the fungus.

How Cresemba 200Mg Injection Works

Cresemba 200Mg Injection contains Isavuconazole which works by fungicidal actions by disrupting the biosynthesis of ergosterol,which are essential for their survival and kills fungus that causes infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cresemba 200Mg Injection

  • Headache
  • Decreased appetite
  • Sleepiness
  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Chest pain

What if I have taken an overdose of Cresemba 200Mg Injection

As Cresemba 200Mg Injection is a parenteral formulation, the chance of overdose may be less. However, keep track of your medicine as an overdose of Cresemba 200Mg Injection may cause serious side effects. Seek immediate medical attention if you observe any side effects.

Drug Warnings

If you are allergic to Cresemba 200Mg Injection or any other medicines, please tell your doctor. Cresemba 200Mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Cresemba 200Mg Injection. Avoid breastfeeding while taking Cresemba 200Mg Injection. Drive only if you are alert after taking Cresemba 200Mg Injection as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Cresemba 200Mg Injection as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interactions

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IsavuconazoleRitonavir
Critical
IsavuconazoleFosamprenavir
Critical

Drug-Drug Interactions

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IsavuconazoleRitonavir
Critical
How does the drug interact with Cresemba 200Mg Injection:
Taking Cresemba 200Mg Injection with Ritonavir may significantly increase the blood levels of Cresemba 200Mg Injection, which may increase the risk of side effects.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like nausea, vomiting, loose stools, light color stools or dark urine, consult a doctor. Do not discontinue any medications without consulting a doctor.
IsavuconazoleFosamprenavir
Critical
How does the drug interact with Cresemba 200Mg Injection:
When Fosamprenavir is taken with Cresemba 200Mg Injection, it can increase the risk of side effects like liver damage.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Fosamprenavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazoleSaquinavir
Critical
How does the drug interact with Cresemba 200Mg Injection:
When Cresemba 200Mg Injection is taken with Saquinavir, it can increase the risk of liver damage.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazolePrimidone
Critical
How does the drug interact with Cresemba 200Mg Injection:
Taking Cresemba 200Mg Injection with primidone may decrease the blood levels of Cresemba 200Mg Injection and reduce its effectiveness.

How to manage the interaction:
Taking Cresemba 200Mg Injection with primidone is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazolePhenytoin
Critical
How does the drug interact with Cresemba 200Mg Injection:
Co-administration of phenytoin and Cresemba 200Mg Injection may significantly reduce the blood levels of Cresemba 200Mg Injection, which may make Cresemba 200Mg Injection less effective in treating your condition.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Phenytoin is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IsavuconazoleCeritinib
Critical
How does the drug interact with Cresemba 200Mg Injection:
Taking ceritinib with Cresemba 200Mg Injection may significantly increase the blood levels of Cresemba 200Mg Injection.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Ceritinib is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loose stools, yellow discoloration of skin and eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazolePhenobarbital
Critical
How does the drug interact with Cresemba 200Mg Injection:
When Cresemba 200Mg Injection is taken with Phenobarbital, may decrease the blood levels of Cresemba 200Mg Injection, which may make Cresemba 200Mg Injection less effective.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Phenobarbital is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
IsavuconazoleItraconazole
Critical
How does the drug interact with Cresemba 200Mg Injection:
The blood levels and effects of Cresemba 200Mg Injection may be significantly enhanced by taking Itraconazole along with it.

How to manage the interaction:
Co-administration of Cresemba 200Mg Injection and Itraconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazolePosaconazole
Critical
How does the drug interact with Cresemba 200Mg Injection:
When Cresemba 200Mg Injection is taken with Posaconazole, it can increase the levels of Cresemba 200Mg Injection in the blood.

How to manage the interaction:
Although there is an interaction between Cresemba 200Mg Injection and posaconazole, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazoleCarbamazepine
Critical
How does the drug interact with Cresemba 200Mg Injection:
When Carbamazepine and Cresemba 200Mg Injection are taken together, carbamazepine will reduce the effectiveness of the Cresemba 200Mg Injection.

How to manage the interaction:
Taking Cresemba 200Mg Injection with Carbamazepine is not recommended, it can be taken if prescribed by the doctor. Do not discontinue any medications without doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
  • Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
  • Bandage all wounds until they heal to prevent fungal infections.
  • Wash your hands frequently and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Cresemba 200Mg Injection Substitute

Substitutes safety advice
  • Isuvaz 200 mg Infusion 1's

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  • Isavufic 200 mg Injection 1's

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    11905.60per tablet
  • Isavulet 200 mg Powder For Solution Infusion 1's

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    12000.00per tablet
  • Zisavel 200 mg Infusion 1's

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    14289.00per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Cresemba 200Mg Injection as it may increase the risk of liver damage.

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Pregnancy

Consult your doctor

Cresemba 200Mg Injection is not recommended during pregnancy except in patients with severe or potentially life-threatening fungal infections in whom Cresemba 200Mg Injection may be used if the doctor thinks the benefits outweigh the risks. Therefore, please inform your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Cresemba 200Mg Injection. Please inform your doctor if you are breastfeeding.

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Driving

Caution

Drive only if you are alert after taking Cresemba 200Mg Injection as it may cause drowsiness, confusion or dizziness.

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Liver

Caution

Inform your doctor if you have liver problems before receiving Cresemba 200Mg Injection as may worsen your condition. Your doctor may adjust the dose as required based on your condition.

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Kidney

Caution

The use of Cresemba 200Mg Injection in patients with severe Kidney impairment is not established. Inform your doctor if you have kidney problems before receiving Cresemba 200Mg Injection as may worsen your condition. Your doctor may adjust the dose as required based on your condition.

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Children

Unsafe

Cresemba 200Mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established.

FAQs

Cresemba 200Mg Injection is used to treat Invasive aspergillosis and Mucormycosis.

Cresemba 200Mg Injection contains Isavuconazole which works by inhibiting the synthesis of fungal cell membranes which are essential for their survival. Thereby, Cresemba 200Mg Injection kills or inhibits the growth of the fungus.

Mucormycosis is not contagious. Mucormycosis is a severe fungal infection of the skin or respiratory system that occurs in people with a weakened immune system.

Cresemba 200Mg Injection may cause headaches as a common side effect. However, if the condition persists or worsens, please consult a doctor.

You are not recommended to take Cresemba 200Mg Injection with ketoconazole as it may increase the levels of Cresemba 200Mg Injection in your blood and increase the risk of side effects such as diarrhoea, vomiting, nausea or liver problems. However, please consult your doctor before taking Cresemba 200Mg Injection with other medicines.

Cresemba 200Mg Injection should be used with caution in patients with liver problems as Cresemba 200Mg Injection may increase liver enzymes. Thus, monitoring of liver enzymes is advised while taking Cresemba 200Mg Injection. However, you are recommended to inform your doctor if you have any liver problems.

Country of origin

UNITED KINGDOM

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - CRE0248

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