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About Combunex 800 Tablet
Combunex 800 Tablet belongs to the group of medications called ‘antituberculosis agents’ primarily used in the treatment of tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. Combunex 800 Tablet does not work against infections caused by the virus.
Combunex 800 Tablet contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism.
Take Combunex 800 Tablet exactly as prescribed by the doctor. Combunex 800 Tablet may cause side effects such as weakness, malaise (general discomfort), fatigue (feeling tired), loss of appetite, nausea or vomiting, dark urine, pale stools, jaundice (yellowing of the skin or whites of the eyes) and vision problems. Inform your doctor immediately if any of these side effects persist or get worse.
It is not recommended to take Combunex 800 Tablet if you are allergic to any contents of it. Combunex 800 Tablet is not recommended for patients with severe liver problems and sight problems. Before taking Combunex 800 Tablet , inform your doctor if you have kidney problems, epilepsy (fits), diabetes, alcohol abuse, psychosis, malnourishment, HIV infection, and extra-pulmonary TB (TB infection outside the lungs). Combunex 800 Tablet should be used with caution in pregnant and breastfeeding women. Dose adjustments may be required in children and elderly people. Combunex 800 Tablet may interact with alcohol and increase the risk of liver damage. Combunex 800 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Uses of Combunex 800 Tablet
Medicinal Benefits
Combunex 800 Tablet contains Isoniazid and Ethambutol, which is a fixed-dose combination used to treat tuberculosis (TB). Combination therapy reduces the development of drug resistance (reduction in the effectiveness of medication) as the bacteria causing TB develops drug resistance easily when monotherapy is given even for shorter periods. Combunex 800 Tablet helps to reduce the symptoms and control the disease effectively.
Side Effects of Combunex 800 Tablet
Directions for Use
Storage
Drug Warnings
It is advised to get your eyesight checked before taking Combunex 800 Tablet . If you notice any changes in your vision while using this medicine, stop taking this medicine and immediately inform your doctor. In most cases, the vision change is temporary and sight returns to normal. However, it might take a longer time for eyesight to recover in some cases or the change might be permanent. If you develop jaundice (yellowing of the skin and whites of the eyes), loss of appetite, nausea, vomiting, or malaise, inform your doctor immediately, as these effects may be a sign of hepatitis (liver disease). In these cases, the doctor may advise you to undergo liver function tests and provide the necessary treatment.
Therapeutic Class
Drug-Drug Interactions
Drug-Food Interactions
Diet & Lifestyle Advise
Habit Forming
How Combunex 800 Tablet Works
What if I have taken an overdose of Combunex 800 Tablet
Alcohol
Caution
Consumption of alcohol may increase the risk of side-effects and worsen the condition.
Pregnancy
Caution
Combunex 800 Tablet should be used with caution in pregnant women. It is given to pregnant women only if clinically needed when the benefits outweigh the risks.
Breast Feeding
Caution
Combunex 800 Tablet should be used with caution in breastfeeding mothers. It is given to breastfeeding mothers only when the benefits outweigh the risks.
Driving
Caution
Combunex 800 Tablet may cause dizziness in some people. So, do not drive or operate heavy machinery if you are not fully alert.
Liver
Caution
Combunex 800 Tablet is not recommended for patients with severe liver problems. In mild to moderate liver diseases, the dose may have to be adjusted by your doctor.
Kidney
Caution
Combunex 800 Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
Caution
Combunex 800 Tablet should be used with caution in children. The dose may have to be adjusted based on age, body weight and healthy history of the child.
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