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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

COMBITAZ 1G+125MG INJECTION is used to treat various bacterial infections in the body. It contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, it helps to treat bacterial infections. Common side effects of this medication are redness and swelling at the injection site, headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, and muscle spasms.

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About COMBITAZ 1G+125MG INJECTION

COMBITAZ 1G+125MG INJECTION belongs to a class of medication called cephalosporin antibiotics. It is used to treat various bacterial infections in the body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

COMBITAZ 1G+125MG INJECTION contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, COMBITAZ 1G+125MG INJECTION helps to treat bacterial infections.

Sometimes, you may experience redness and swelling at the injection site, headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, and muscle spasms. Most of these side effects of COMBITAZ 1G+125MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking COMBITAZ 1G+125MG INJECTION, tell your doctor if you are pregnant or breastfeeding. Inform your doctor if you are allergic to any foods or medications. Drive with caution since COMBITAZ 1G+125MG INJECTION may cause dizziness. Before taking COMBITAZ 1G+125MG INJECTION, inform your doctor about your medical history and other medications you are currently taking in order to rule out any potential negative effects.

Uses of COMBITAZ 1G+125MG INJECTION

Treatment of Bacterial infections

Directions for Use

COMBITAZ 1G+125MG INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

COMBITAZ 1G+125MG INJECTION contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the production of the bacterial cell wall (a protective covering required for survival). Tazobactam reduces bacterial resistance and increases the action of Ceftazidime against bacteria. Together, they aid in the treatment of bacterial infections, including serious, life-threatening infections due to gram-positive bacteria.

How COMBITAZ 1G+125MG INJECTION Works

COMBITAZ 1G+125MG INJECTION contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, COMBITAZ 1G+125MG INJECTION helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of COMBITAZ 1G+125MG INJECTION

  • Redness and swelling on the injection site
  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Muscle spasm
  • Elevated liver enzymes

What if I have taken an overdose of COMBITAZ 1G+125MG INJECTION

As COMBITAZ 1G+125MG INJECTION is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of COMBITAZ 1G+125MG INJECTION may include muscle stiffness, uncontrolled muscle movements, seizure, or coma.

Drug Warnings

Before taking the COMBITAZ 1G+125MG INJECTION, inform your doctor about all your medical conditions, sensitivities, and all medications (including herbals and supplements) you are using. If you are pregnant or breastfeeding, inform your doctor before taking COMBITAZ 1G+125MG INJECTION. You are recommended to complete the full course of COMBITAZ 1G+125MG INJECTION as your doctor prescribes for effective results. COMBITAZ 1G+125MG INJECTION should not be administered if you are currently on any vaccinations or are scheduled for the same. COMBITAZ 1G+125MG INJECTION should be used with caution in those with Clostridium difficile-associated diarrhoea. Drive only if you are alert, as COMBITAZ 1G+125MG INJECTION may cause dizziness.

Drug-Drug Interactions

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CeftazidimeBCG vaccine
Critical
CeftazidimeCholera, live attenuated
Severe

Drug-Drug Interactions

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CeftazidimeBCG vaccine
Critical
How does the drug interact with COMBITAZ 1G+125MG INJECTION:
When BCG vaccine is used with COMBITAZ 1G+125MG INJECTION, its effectiveness may be reduced.

How to manage the interaction:
Taking COMBITAZ 1G+125MG INJECTION with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
CeftazidimeCholera, live attenuated
Severe
How does the drug interact with COMBITAZ 1G+125MG INJECTION:
Taking the cholera vaccine after or along with COMBITAZ 1G+125MG INJECTION may reduce the activity of the vaccine.

How to manage the interaction:
Although taking COMBITAZ 1G+125MG INJECTION with Cholera, live attenuated can possibly result in an interaction, but it can be taken if your doctor has advised it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without a doctor's advice.
CeftazidimeCholera vaccines
Severe
How does the drug interact with COMBITAZ 1G+125MG INJECTION:
Taking the cholera vaccine after or along with COMBITAZ 1G+125MG INJECTION may reduce the activity of the vaccine.

How to manage the interaction:
Although there is a possible interaction between COMBITAZ 1G+125MG INJECTION and Cholera vaccines, you can take these medicines together if prescribed by your doctor. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of COMBITAZ 1G+125MG INJECTION to restore some healthy intestinal bacteria that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after an antibiotic course. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
  • Avoid taking much calcium-enriched foods and drinks as it might affect the working of COMBITAZ 1G+125MG INJECTION.
    Avoid intake of alcoholic beverages with COMBITAZ 1G+125MG INJECTION as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the COMBITAZ 1G+125MG INJECTION in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

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Alcohol

Caution

The interaction of COMBITAZ 1G+125MG INJECTION with alcohol is unknown. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

The safety of COMBITAZ 1G+125MG INJECTION in pregnant women is unknown. Therefore, please inform your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Consult the doctor if you are breastfeeding. Consider the importance of the medicine to the mother when deciding whether to discontinue nursing or the medicine.

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Driving

Caution

COMBITAZ 1G+125MG INJECTION may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking COMBITAZ 1G+125MG INJECTION.

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Liver

Caution

Take COMBITAZ 1G+125MG INJECTION with caution, especially if you have a history of liver diseases. Inform your doctor before receiving the COMBITAZ 1G+125MG INJECTION if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Take COMBITAZ 1G+125MG INJECTION with caution, especially if you have a history of kidney diseases. Inform your doctor before receiving the COMBITAZ 1G+125MG INJECTION if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Limited information is available regarding the usage of COMBITAZ 1G+125MG INJECTION in children, so please consult a doctor if you have any concerns.

FAQs

COMBITAZ 1G+125MG INJECTION is used to treat Bacterial infections.
Ceftazidime and Tazobactam are both present in COMBITAZ 1G+125MG INJECTION. Ceftazidime works by preventing the production of the bacterial cell wall (a protective covering required for survival). Tazobactam reduces bacterial resistance while increasing the efficacy of Ceftazidime against bacteria. Together, COMBITAZ 1G+125MG INJECTION aids in the treatment of bacterial illnesses.
COMBITAZ 1G+125MG INJECTION may Increase liver enzymes. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking COMBITAZ 1G+125MG INJECTION.
COMBITAZ 1G+125MG INJECTION may cause diarrhoea as a common side effect. However, if the condition persists or worsens, consult a doctor immediately.
If you are being treated with COMBITAZ 1G+125MG INJECTION or have been treated within the last three days, you should talk to your doctor before taking the vaccine. Antibiotics like COMBITAZ 1G+125MG INJECTION can reduce the vaccine's activity.
COMBITAZ 1G+125MG INJECTION usually begins to work shortly after you start taking it. However, it may take a few days to eliminate all harmful bacteria and improve your symptoms.
If you do not get better after using COMBITAZ 1G+125MG INJECTION, reach out to your doctor immediately. They might re-evaluate your condition, investigate potential issues, and modify your treatment accordingly.
COMBITAZ 1G+125MG INJECTION causes side effects such as headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, muscle spasm, and elevated liver enzymes. Contact a doctor if these side effects persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - COM0033

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