Cofrav Syrup

Cofrav Syrup belongs to a class of respiratory medication called ‘expectorant' primarily used to treat vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder) having a cough. It helps in dissolving hard phlegm (sputum/cough) which makes breathing difficult usually in respiratory problems like allergies, sinusitis, common cold, bronchitis, flu, etc. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection.

Cofrav Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine (mucolytic agent), Terbutaline (bronchodilator), and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier for airway passage. Bromhexine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose, making it easier to cough it out. Terbutaline belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Take Cofrav Syrup as prescribed. Your doctor will recommend how often you take Cofrav Syrup based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset, and fast heartbeats. Most of these side effects of Cofrav Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Cofrav Syrup or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, it is advised to inform your doctor before taking Cofrav Syrup. Avoid taking Cofrav Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. If you are suffering from fits or have a history of fits, please inform your doctor before taking Cofrav Syrup as it may increase the risk of recurrent fits. If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Cofrav Syrup. If you have diabetes, fits, high blood pressure, glaucoma, cough for a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Cofrav Syrup.

Cofrav Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine (mucolytic agent), Terbutaline (bronchodilator), and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier for airway passage. Bromhexine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose, making it easier to cough it out. Terbutaline belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

• Diarrhoea
• Nausea
• Vomiting
• Drowsiness
• Headache
• Dizziness
• Skin rash
• Tremor
• Stomach upset
• Fast heartbeats

If you are known to be allergic to Cofrav Syrup or any other medicines, pregnant or planning for pregnancy, it is advised to inform your doctor before taking Cofrav Syrup. Avoid taking Cofrav Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. If you are suffering from fits (epilepsy) or have a history of fits, please inform your doctor before taking Cofrav Syrup as it may increase the risk of recurrent fits. If you have diabetes, fits, high blood pressure, glaucoma, cough from a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Cofrav Syrup.

Drug-Drug Interaction: Cofrav Syrup may have interaction with medicines used to lower high blood pressure (propranolol), hormone (epinephrine), water pills (furosemide), anti-allergic drugs (promethazine), uterine stimulant (oxytocin), bronchodilators (formoterol, dyphylline), anti-sickness drug (ondansetron).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, fits, high blood pressure, glaucoma, cough from a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Cofrav Syrup.

• PROPRANOLOL
• EPINEPHRINE
• FUROSEMIDE
• PROMETHAZINE
• OXYTOCIN
• FORMOTEROL
• DYPHYLLINE
• ONDANSETRON

• Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
• Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
• Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Regularly monitor blood sugar levels while taking Cofrav Syrup if you have diabetes as it may increase blood sugar levels.

Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-colored, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.