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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:54 PM IST
Crf-X Syrup is used to treat cough associated with excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder). It helps in dissolving hard phlegm (sputum/cough) which makes breathing difficult usually in respiratory problems like allergies, sinusitis, common cold, bronchitis, flu, etc. It works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier to cough out. It relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Some people may experience side effects such as diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset, and fast heartbeats.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Acme Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Crf-X Syrup

Crf-X Syrup belongs to a class of respiratory medication called ‘expectorant' primarily used to treat vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder) having a cough. It helps in dissolving hard phlegm (sputum/cough) which makes breathing difficult usually in respiratory problems like allergies, sinusitis, common cold, bronchitis, flu, etc. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection.

Crf-X Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine (mucolytic agent), Terbutaline (bronchodilator), and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier for airway passage. Bromhexine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose, making it easier to cough it out. Terbutaline belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Take Crf-X Syrup as prescribed. Your doctor will recommend how often you take Crf-X Syrup based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset, and fast heartbeats. Most of these side effects of Crf-X Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Crf-X Syrup or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, it is advised to inform your doctor before taking Crf-X Syrup . Avoid taking Crf-X Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. If you are suffering from fits or have a history of fits, please inform your doctor before taking Crf-X Syrup as it may increase the risk of recurrent fits. If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Crf-X Syrup . If you have diabetes, fits, high blood pressure, glaucoma, cough for a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Crf-X Syrup .

Uses of Crf-X Syrup

Treatment of Cough

Medicinal Benefits

Crf-X Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine (mucolytic agent), Terbutaline (bronchodilator), and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus, and making it easier for airway passage. Bromhexine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose, making it easier to cough it out. Terbutaline belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Directions for Use

Shake the bottle well before use. Check the label for directions before using Crf-X Syrup and take it with or without food as prescribed by your doctor with the help of a measuring cup that is provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Crf-X Syrup

  • Diarrhoea
  • Nausea
  • Vomiting
  • Drowsiness
  • Headache
  • Dizziness
  • Skin rash
  • Tremor
  • Stomach upset
  • Fast heartbeats

Drug Warnings

If you are known to be allergic to Crf-X Syrup or any other medicines, pregnant or planning for pregnancy, it is advised to inform your doctor before taking Crf-X Syrup . Avoid taking Crf-X Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. If you are suffering from fits (epilepsy) or have a history of fits, please inform your doctor before taking Crf-X Syrup as it may increase the risk of recurrent fits. If you have diabetes, fits, high blood pressure, glaucoma, cough from a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Crf-X Syrup .

Drug Interactions

Drug-Drug Interaction: Crf-X Syrup may have interaction with medicines used to lower high blood pressure (propranolol), hormone (epinephrine), water pills (furosemide), anti-allergic drugs (promethazine), uterine stimulant (oxytocin), bronchodilators (formoterol, dyphylline), anti-sickness drug (ondansetron).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, fits, high blood pressure, glaucoma, cough from a long time, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems, please inform your doctor before taking Crf-X Syrup .

Drug-Drug Interactions Checker List

  • PROPRANOLOL
  • EPINEPHRINE
  • FUROSEMIDE
  • PROMETHAZINE
  • OXYTOCIN
  • FORMOTEROL
  • DYPHYLLINE
  • ONDANSETRON

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Special Advise

Regularly monitor blood sugar levels while taking Crf-X Syrup if you have diabetes as it may increase blood sugar levels.

Disease/Condition Glossary

Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-colored, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

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Alcohol

Caution

Interaction of alcohol with Crf-X Syrup is unknown. Please consult a doctor before consuming alcohol with Crf-X Syrup .

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Pregnancy

Unsafe

Crf-X Syrup is contraindicated in pregnant women, especially in the first 3 months of pregnancy as it may cause birth defects. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Crf-X Syrup is excreted in breast milk and may cause adverse effects in the baby. Hence, it is not recommended for breastfeeding mothers.

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Driving

Caution

Crf-X Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Crf-X Syrup .

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Liver

Safe if prescribed

If you have any concerns regarding the use of Crf-X Syrup in patients with Liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Crf-X Syrup in patients with Kidney problems, please consult a doctor.

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Children

Caution

Crf-X Syrup should be used with caution in children, especially below 2 years of age if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - CRF0001

Author Details

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FAQs

Crf-X Syrup is used to treat viscous and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder) having a cough. It helps in dissolving hard phlegm (sputum/cough) which makes breathing difficult usually in respiratory problems like allergies, sinusitis, common cold, bronchitis, flu, etc.
Crf-X Syrup contains Guaifenesin, Bromhexine, Terbutaline and Menthol. Guaifenesin is an expectorant that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from airways. Bromhexine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in lungs, windpipe and nose. Thereby, helps to cough out easily. Terbutaline is a bronchodilator that relaxes muscles and widens the airways. Thereby, makes breathing easier. Menthol is a cooling agent that produces cooling sensation and provides relief from minor throat irritation.
Yes, Crf-X Syrup may cause drowsiness or dizziness. It is not necessary for everyone taking Crf-X Syrup to experience this side effect. Therefore, avoid driving if you feel drowsy or dizzy after taking Crf-X Syrup .
Crf-X Syrup should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Crf-X Syrup as it may increase blood sugar levels.
No, you are not recommended to take propranolol with Crf-X Syrup as it may reduce the effectiveness of both the medicines. Also, propranolol may cause narrowing of airways sometimes, which may trigger severe asthmatic attacks or worsen breathing problems. However, you are recommended to consult a doctor before using other medicines with Crf-X Syrup .
Crf-X Syrup should be used with caution in hyperthyroid (overactive thyroid) patients as it may worsen the condition. Inform your doctor if have hyperthyroidism before taking Crf-X Syrup so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while taking Crf-X Syrup .
You are recommended to take Crf-X Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Crf-X Syrup , please consult your doctor.
No, you are not recommended to stop taking Crf-X Syrup without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Crf-X Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Crf-X Syrup , please consult your doctor.
The dosage can vary based on the individual's age, medical condition, and the severity of symptoms. Follow the specific dosage instructions provided by your doctor.
Take Crf-X Syrup with or without food. Your doctor will recommend the best time to take Crf-X Syrup . Follow your doctor’s instructions.
Crf-X Syrup can be given to elderly patients if prescribed by your doctor. Elderly patients may be more sensitive to the side effects of Crf-X Syrup , such as dizziness, drowsiness, and gastrointestinal issues. Therefore, consult a doctor before giving Crf-X Syrup to elderly patients.
Crf-X Syrup is recommended for wet cough. Therefore, consult your doctor for a medication that specifically targets dry cough.
Crf-X Syrup can be taken with or without food as advised by the doctor with the help of a measuring cup that is provided with the pack. Do not exceed recommended dose.
No, taking Crf-X Syrup in a dose higher than recommended will not make it more effective and can actually be harmful. Crf-X Syrup overdose can increase the risk of serious side effects and potentially lead to health complications. It's important to follow your doctor's prescribed dosage and instruction. However, if you feel that the current dose is not effective, please consult your doctor.
Store Crf-X Syrup at room temperature in a cool and dry place away from light. Keep it out of reach of children.
The common side effects of Crf-X Syrup are diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset, and fast heartbeats. If any of these side effects persist or worsen, please consult your doctor.

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