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Coflam MR 400mg/325mg/250mg Tablet

Coflam MR 400mg/325mg/250mg Tablet

Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Parasol Laboratories

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Coflam MR 400mg/325mg/250mg Tablet

Coflam MR 400mg/325mg/250mg Tablet is used in the reduction of musculoskeletal pain and muscle spasm due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long-term (chronic) in nature. Musculoskeletal pain can be caused due to soft tissue (muscle, tendon or ligaments) injury. Extreme tissue pain and inflammation caused by sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

Coflam MR 400mg/325mg/250mg Tablet contains Ibuprofen, Paracetamol and Chlorzoxazone. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Ibuprofen. Chlorzoxazone is a muscle relaxant that helps by blocking nerve impulses or pain sensations sent by the brain and causes the relaxation of muscles.

Take Coflam MR 400mg/325mg/250mg Tablet as prescribed. Like all medicines, Coflam MR 400mg/325mg/250mg Tablet may cause side effects, although not everybody gets them. Nausea, indigestion,  diarrhoea, drowsiness, dizziness, heartburn, stomach pain and restlessness are a few common side effects of Coflam MR 400mg/325mg/250mg Tablet.

Do not take Coflam MR 400mg/325mg/250mg Tablet if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Coflam MR 400mg/325mg/250mg Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days.

Uses of Coflam MR 400mg/325mg/250mg Tablet

Treatment of Musculoskeletal pain and muscle spasms.

Medicinal Benefits

Coflam MR 400mg/325mg/250mg Tablet is composed of ibuprofen, chlorzoxazone and paracetamol primarily used to treat mild to moderate pain. Coflam MR 400mg/325mg/250mg Tablet plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Coflam MR 400mg/325mg/250mg Tablet relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Ibuprofen works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol has the advantage of producing lesser gastric irritation compared to other painkillers like aspirin. So, it is well tolerated in almost all age groups. Chlorzoxazone benefits in relaxing muscles to treat any type of musculoskeletal conditions like sprain, pain or injury. It is mainly prescribed for sports-related injuries. Overall it relieves muscle spasms or stiffness of musculoskeletal joints, thereby improving its movement.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Coflam MR 400mg/325mg/250mg Tablet

  • Nausea

  • Indigestion

  • Diarrhoea

  • Drowsiness

  • Dizziness

  • Heartburn

  • Stomach pain

  • Restlessness

Drug Warnings

Coflam MR 400mg/325mg/250mg Tablet should be taken with caution if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery, heart disease or history of allergy to any painkillers or analgesic. Avoid driving while consuming Coflam MR 400mg/325mg/250mg Tablet as it can cause dizziness in some individuals and hamper your focus and reflexes. Avoid concomitant consumption of drugs containing the same chemicals as Coflam MR 400mg/325mg/250mg Tablet as it can lead to overdosage and unwanted side effects. Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Coflam MR 400mg/325mg/250mg Tablet. Avoid consuming alcohol while you are on Coflam MR 400mg/325mg/250mg Tablet.

Drug Interactions

Drug-Drug Interaction: Coflam MR 400mg/325mg/250mg Tablet is shown to interact with various drugs. Some of them include pain killers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), lithium, anticancer/antimetabolites (methotrexate), blood thinner or anticoagulant (warfarin, coumadin, jantoven), blood pressure or heart medicine, nausea medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), a steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophyllines, ephedrine), cholesterol-reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of Coflam MR 400mg/325mg/250mg Tablet and may alter its efficacy.

Drug-Food Interaction: Excessive intake of caffeine-containing food or drinks like coffee, tea, chocolate and some fizzy drinks should be avoided while taking Coflam MR 400mg/325mg/250mg Tablet. Taking them together may lead to drowsiness and dizziness and sleepiness. And also, consuming alcohol along with Coflam MR 400mg/325mg/250mg Tablet can cause excessive ingestion of alcohol and potentiate liver damage action of paracetamol. 

Drug-Disease Interaction: Coflam MR 400mg/325mg/250mg Tablet should not recommend for people having bleeding disorders, like haemophilia, von Willebrand disease or low blood platelets. Besides this, it should not be given to children suffering from influenza (flu) or chickenpox. It should also be avoided in case of the presence of gastric or duodenal ulcers.

Drug-Drug Interactions Checker List

  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LITHIUM
  • METHOTREXATE
  • WARFARIN
  • COUMADIN
  • JANTOVEN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • FUROSEMIDE
  • PREDNISONE
  • CIPROFLOXACIN
  • THEOPHYLLINE
  • EPHEDRINE
  • CHOLESTYRAMINE
  • DULOXETINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, calcium enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.

  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long term immobility is harmful in conditions like arthritis.  Use back support like a rolled up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a foot rest if required.

Special Advise

Stop using Coflam MR 400mg/325mg/250mg Tablet and consult your doctor immediately if you are having bleeding from the rectum (back passage), have black sticky bowel motions (stools) or bloody diarrhoea.

Disease/Condition Glossary

Pain can be temporary (acute) or long-term (chronic) in nature. Musculoskeletal pain can be caused due to soft tissue (muscle, tendon or ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

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Alcohol

Caution

Taking Coflam MR 400mg/325mg/250mg Tablet with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Coflam MR 400mg/325mg/250mg Tablet.

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Pregnancy

Unsafe

Use of Coflam MR 400mg/325mg/250mg Tablet during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

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Breast Feeding

Caution

Take Coflam MR 400mg/325mg/250mg Tablet only if prescribed by your doctor.

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Driving

Unsafe

After taking Coflam MR 400mg/325mg/250mg Tablet you may notice dizziness, sleepiness, drowsiness or fatigue as it contain paracetamol which causes sedation. So, in this you should stop taking Coflam MR 400mg/325mg/250mg Tablet and contact your doctor.

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Liver

Caution

Coflam MR 400mg/325mg/250mg Tablet to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Coflam MR 400mg/325mg/250mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Coflam MR 400mg/325mg/250mg Tablet is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated. It should be use only when prescribed by a child specialist.

Country of origin

India
Other Info - CO32682

FAQs

Coflam MR 400mg/325mg/250mg Tablet is used to relieve musculoskeletal pain and muscle spasms due to tissue injury. It may also be indicated in post-surgery inflammation and oedema (swollen tissue with fluid).
Coflam MR 400mg/325mg/250mg Tablet when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.
Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or chlorzoxazone. As, it may lead to overdosage leading to unpleasant side effects.
It depends on whether your cough and cold pills contain ibuprofen, chlorzoxazone and paracetamol or not. If it contains these two medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.
Coflam MR 400mg/325mg/250mg Tablet is known to be contra-indicated in patients allergic to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of heart failure, high blood pressure, stomach ulcer and kidney/liver disease.

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