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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 13, 2024 | 9:12 AM IST
Clopixol Depot Injection 1 ml is used to treat schizophrenia (a mental illness) and other psychotic disorders. It contains Zuclopenthixol, which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thus, it helps control psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps improve feelings, disturbed thoughts, and behaviour.
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Manufacturer/Marketer

Lundbeck India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Clopixol Depot Injection 1 ml

Clopixol Depot Injection 1 ml belongs to a class of medications called antipsychotics used to treat schizophrenia (a mental illness) and other psychotic disorders. Additionally, Clopixol Depot Injection 1 ml may be used in the initial treatment of mania over the short term. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Clopixol Depot Injection 1 ml contains Zuclopenthixol which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Clopixol Depot Injection 1 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbed thoughts and behaviour.

Clopixol Depot Injection 1 ml will be administered by a healthcare professional; do not self-administer. Some people may experience sleepiness, akathisia (inability to sit still or remain motionless), dry mouth, hyperkinesia (involuntary movements), hypokinesia (slow or diminished movements), constipation, muscle pain, tremor, or headache. Most of these side effects of Clopixol Depot Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zuclopenthixol or any other medicines, please tell your doctor. Clopixol Depot Injection 1 ml is not recommended for children. Clopixol Depot Injection 1 ml is not recommended during pregnancy unless clearly necessary because using it during the third trimester may cause adverse effects in the baby, such as breathing problems, muscle stiffness or weakness, shaking, etc. Clopixol Depot Injection 1 ml may be excreted in breast milk. Therefore, avoid taking Clopixol Depot Injection 1 ml if you are breastfeeding. Do not consume alcohol with Clopixol Depot Injection 1 ml as it may increase the sedative effects of alcohol. Drive only if you are alert, as Clopixol Depot Injection 1 ml may cause dizziness, double vision or drowsiness.

Uses of Clopixol Depot Injection 1 ml

Treatment of Schizophrenia, Mania and other psychotic disorders

Medicinal Benefits

Clopixol Depot Injection 1 ml contains Zuclopenthixol used to treat schizophrenia (a mental illness) and other psychotic disorders. Additionally, Clopixol Depot Injection 1 ml may be used in the initial treatment of mania over the short term. Clopixol Depot Injection 1 ml inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Clopixol Depot Injection 1 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbed thoughts and behaviour. Also, Clopixol Depot Injection 1 ml produces a calming effect and controls hallucinations, aggression and delusions (false beliefs).

Directions for Use

Clopixol Depot Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clopixol Depot Injection 1 ml

  • Sleepiness
  • Akathisia (inability to sit still or remain motionless)
  • Dry mouth
  • Hyperkinesia (involuntary movements)
  • Hypokinesia (slow or diminished movements)
  • Constipation
  • Muscle pain
  • Tremor
  • Headache

Drug Warnings

If you are allergic to Zuclopenthixol or any other medicines, please tell your doctor. If you have liver, kidney, heart or thyroid problems, inform your doctor before taking Clopixol Depot Injection 1 ml. Clopixol Depot Injection 1 ml is not recommended for children. Clopixol Depot Injection 1 ml is not recommended during pregnancy unless clearly necessary as using it during third trimester may cause adverse effects in the baby such as breathing problems, muscle stiffness or weakness, shaking, etc. Clopixol Depot Injection 1 ml may be excreted in breast milk. Therefore, avoid taking Clopixol Depot Injection 1 ml if you are breastfeeding. Inform your surgeon, anaesthetist or dentist before any surgery that you are on treatment with Clopixol Depot Injection 1 ml. Do not consume alcohol with Clopixol Depot Injection 1 ml as it may increase sedative effects of alcohol. Drive only if you are alert as Clopixol Depot Injection 1 ml may cause dizziness, double vision or drowsiness.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking high blood pressure-lowering medicines (hydralazine, doxazosin, guanethidine, methyldopa, clonidine), antibiotics (erythromycin, moxifloxacin), antimanic drug (lithium), heart-related medicines (quinidine, amiodarone, sotalol, dofetilide, digoxin), hormone (epinephrine), gastroprokinetic agent (cisapride), blood thinner (warfarin), antiemetic (metoclopramide), drugs to treat worm infections (piperazine), antiparkinson drug (levodopa), steroid (prednisolone) or other medicines.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have fits, high blood pressure, asthma, low potassium or magnesium in the blood, Parkinson’s disease, diabetes, blood clots, myasthenia gravis (muscle weakness), have a family history of irregular heartbeats or blood clots, liver, kidney, heart or thyroid problems, inform your doctor before taking Clopixol Depot Injection 1 ml.

Drug-Drug Interactions Checker List

  • HYDRALAZINE
  • DOXAZOSIN
  • GUANETHIDINE
  • METHYLDOPA
  • CLONIDINE
  • ERYTHROMYCIN
  • MOXIFLOXACIN
  • LITHIUM
  • QUINIDINE
  • AMIODARONE
  • SOTALOL
  • DOFETILIDE
  • DIGOXIN
  • EPINEPHRINE
  • CISAPRIDE
  • WARFARIN
  • METOCLOPRAMIDE
  • PIPERAZINE
  • LEVODOPA
  • PREDNISOLONE

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise and maintain healthy body weight.
  • Maintain a diet rich in fruits, vegetables and whole grains.
  • Follow a regular sleep pattern. Do not take a nap during day time.
  • Avoid watching t and using mobiles or laptops just before bedtime.
  • Avoid alcohol consumption as it may increase drowsiness.

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects the ability of a person to feel, think and behave clearly. The symptoms include hallucinations, thought or movement disorders, delusions (misbelief), lack of emotion, sleep problems, isolation from family and friends, and difficulty in daily activities.

Mania: It is a mental condition which causes intense excitement, high energy and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep patterns, high levels of stress and alcohol intake. Consult a doctor immediately if you have any self-harming or suicidal thoughts.

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Alcohol

Unsafe

Avoid consumption of alcohol with Clopixol Depot Injection 1 ml as it may increase drowsiness.

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Pregnancy

Caution

Clopixol Depot Injection 1 ml is not recommended for use during pregnancy unless clearly necessary. If Clopixol Depot Injection 1 ml is used during the third trimester, it may cause muscle stiffness and/or weakness, shaking, sleepiness, difficulty feeding, and breathing problems in the baby. Therefore, please consult a doctor if you are pregnant or planning for pregnancy before taking Clopixol Depot Injection 1 ml.

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Breast Feeding

Unsafe

Clopixol Depot Injection 1 ml is not recommended for breastfeeding mothers as it may be excreted in breast milk. However, if you have concerns regarding this, please discuss them with your doctor.

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Driving

Unsafe

There is a risk of dizziness, drowsiness or blurred vision after taking Clopixol Depot Injection 1 ml, especially at the beginning of your treatment. Avoid driving or operating machinery if you are not alert.

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Liver

Consult your doctor

If you have liver problems, please consult your doctor before taking Clopixol Depot Injection 1 ml.

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Kidney

Consult your doctor

If you have kidney problems, please consult your doctor before taking Clopixol Depot Injection 1 ml.

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Children

Unsafe

Clopixol Depot Injection 1 ml is not recommended for children as safety and effectiveness were not established.

Country of origin

INDIA

Manufacturer/Marketer address

Lundbeck India Private Limited, H M Towers, I Floor, #58, Brigade Road, Kodihalli BDA, HAL II Stage, 560 025, Bangalore, India
Other Info - CLO0057

Author Details

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FAQs

Clopixol Depot Injection 1 ml is used to treat Schizophrenia, Mania and other psychotic disorders.
Clopixol Depot Injection 1 ml contains Zuclopenthixol which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Clopixol Depot Injection 1 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbed thoughts and behaviour.
Clopixol Depot Injection 1 ml should be used with caution in asthma patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have asthma or other breathing problems before taking Clopixol Depot Injection 1 ml.
It is not recommended to take Clopixol Depot Injection 1 ml before surgery. Therefore, it is advised to inform your surgeon, anaesthetist or dentist before any surgery that you are on treatment with Clopixol Depot Injection 1 ml as it may increase the effects of muscle relaxing drugs, general anaesthesia and drugs used to prevent blood clots.
Clopixol Depot Injection 1 ml may affect fertility as it reduces sexual activity. However, it is a temporary effect. Please consult a doctor if you are planning pregnancy before taking Clopixol Depot Injection 1 ml.
Clopixol Depot Injection 1 ml should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Clopixol Depot Injection 1 ml.
You are not recommended to take Clopixol Depot Injection 1 ml with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Clopixol Depot Injection 1 ml with any other medicines.
Clopixol Depot Injection 1 ml belongs to the group of medications called antipsychotics used to treat schizophrenia (a mental illness) and other psychotic disorders. It can be used for short-term initial treatment for mania if advised by the doctor.
No, you should not discontinue taking Clopixol Depot Injection 1 ml on your own as stopping this medication may cause withdrawal symptoms like nausea, vomiting, diarrhoea, restlessness, anxiety, agitation and insomnia. The doctor will reduce the dose gradually to prevent withdrawal symptoms.
Do not take larger than the prescribed doses. Taking more than the recommended dose does not provide extra relief but it can increase the risk of side effects like coma, hypo or hyperthermia, extreme drowsiness and shock. However, it is unlikely to exceed the recommended dose of Clopixol Depot Injection 1 ml as it will be administered by the doctor.
The side effects of Clopixol Depot Injection 1 ml include dry mouth, mouth and eyeballs, muscle pain, drowsiness, tremor, unusual movement of tongue, fainting, constipation, headache or migraine. Consult the doctor if any of these side effects persist or worsen.

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