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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cilnilot-Trio Tablet is used to treat hypertension (high blood pressure). It works by relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. It reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Also, it removes extra water and certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. In some cases, it may cause side effects such as headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Novolot Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Cilnilot-Trio Tablet

Cilnilot-Trio Tablet belongs to the class of medicines called hypertensives primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.

Cilnilot-Trio Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone together help in lowering raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone (diuretic) removes extra water, certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take Cilnilot-Trio Tablet with food or as advised by the doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on the dose and duration based on your medical condition. You may experience headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Most of these side effects of Cilnilot-Trio Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase the risk of getting stroke and heart diseases. Cilnilot-Trio Tablet should be taken with caution in patients with chest pain (angina), kidney disease, heart failure, low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Cilnilot-Trio Tablet can be prescribed accordingly. Do not use Cilnilot-Trio Tablet if you cannot urinate,  are dehydrated, and increase fluid intake. Please inform your doctor if you are taking any other medicines or are allergic to this medicine. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Cilnilot-Trio Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Cilnilot-Trio Tablet should be taken daily with food to allow its slow absorption and reduce the risk of sudden lowering of blood pressure. Swallow the whole tablet with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Cilnilot-Trio Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Clindipine, and Chlorthalidone, which together help in lowering raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Chlorthalidone is a diuretic that removes extra water, certain electrolytes from the body and efficiently reduces blood pressure.

How Cilnilot-Trio Tablet Works

Cilnilot-Trio Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone together help in lowering raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone (diuretic) removes extra water, certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cilnilot-Trio Tablet

  • Dizziness
  • Headache
  • Peripheral oedema (swelling of legs/hands)
  • Flushing (skin reddening)
  • Rash
  • Taste change
  • Upset stomach

What if I have taken an overdose of Cilnilot-Trio Tablet

Do not take more than the prescribed dose of Cilnilot-Trio Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Cilnilot-Trio Tablet should not be given to the people allergic to Cilnilot-Trio Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Cilnilot-Trio Tablet can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Cilnilot-Trio Tablet and breastfeeding. Grapefruit juice and St. John's wort plant should not be consumed when taking Cilnilot-Trio Tablet as it is contraindicated. Cilnilot-Trio Tablet contain hydrochlorothiazide which can cause hypokalaemia (low potassium), hyponatremia (low sodium) and hypomagnesemia (low magnesium). So regular monitoring of electrolytes is required while taking treatment with Cilnilot-Trio Tablet . Do not take Cilnilot-Trio Tablet if you have low or no urine output, are allergic to other sulfonamide antibiotics, or are taking Aliskiren and have diabetes. Drinking alcohol while using Cilnilot-Trio Tablet can cause you to have low blood pressure, so avoid intake of alcoholic beverages.

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
chlorthalidoneCisapride
Critical

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
How does the drug interact with Cilnilot-Trio Tablet 10's:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Cilnilot-Trio Tablet 10's with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
chlorthalidoneCisapride
Critical
How does the drug interact with Cilnilot-Trio Tablet 10's:
Co-administration of Cilnilot-Trio Tablet 10's and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Cilnilot-Trio Tablet 10's with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
Olmesartan medoxomilEnalapril
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Using enalapril together with Cilnilot-Trio Tablet 10's may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Co-administration of Enalapril with Cilnilot-Trio Tablet 10's may lead to interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilLisinopril
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Coadministration of Cilnilot-Trio Tablet 10's with lisinopril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's together with lisinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilTriamterene
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Taking Cilnilot-Trio Tablet 10's with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilpotassium phosphate
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Using potassium phosphate together with olmesartan may significantly increase potassium levels in the blood.

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's and potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience symptoms such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, consult a doctor. It is crucial that you continue to consume enough fluids while taking these medications. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilTrimethoprim
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Taking Cilnilot-Trio Tablet 10's with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's with trimethoprim may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium iodide
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Coadministration of Cilnilot-Trio Tablet 10's with potassium iodide may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's together with potassium iodide may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilEnalapril
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Coadministration of Cilnilot-Trio Tablet 10's with enalapril can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's together with enalapril may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
Olmesartan medoxomilFosinopril
Severe
How does the drug interact with Cilnilot-Trio Tablet 10's:
Coadministration of Cilnilot-Trio Tablet 10's with fosinopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Cilnilot-Trio Tablet 10's together with fosinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MG+CHLORTHALIDONE-12.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MG+CHLORTHALIDONE-12.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
When Cilnilot-Trio Tablet 10's is taken along with potassium-containing salt substitutes or over-the-counter potassium supplements it may lead to high potassium levels in blood. Avoid taking potassium-containing salt substitutes or over-the-counter potassium supplements with Cilnilot-Trio Tablet 10's as this can lead to high potassium levels in the blood. However, consult a doctor if you experience weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products. 
  • Limit your intake of sodium chloride (table salt) to 2300 mg per day, or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable. 
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques. 
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Cilnilot-Trio Tablet Substitute

Substitutes safety advice
  • Olmin Trio Tablet 10's

    17.42per tablet
  • Olkem Trio 12.5 Tablet 10's

    17.42per tablet
  • Trinexovas 20 Tablet 15's

    15.42per tablet
  • Cilidin Trio Tablet 15's

    17.34per tablet
  • Cetabloc-Trio Tablet 10's

    12.78per tablet
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Alcohol

Unsafe

Cilnilot-Trio Tablet can lower your blood pressure, causing dizziness and drowsiness. It can also cause orthostatic hypotension (a sudden fall in blood pressure while standing). So try to avoid taking Cilnilot-Trio Tablet with alcoholic beverages.

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Pregnancy

Unsafe

Cilnilot-Trio Tablet is pregnancy risk category D medicine which may cause harm to the fetus or unborn baby. So, when pregnancy is detected, discontinue Cilnilot-Trio Tablet as soon as possible and consult the doctor.

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Breast Feeding

Caution

Cilnilot-Trio Tablet passes into the breast milk, but its effect on the baby is not clear. Therefore, it is advisable to contact the doctor before intake of Cilnilot-Trio Tablet .

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Driving

Unsafe

Cilnilot-Trio Tablet may cause side effects, which could affect your ability to drive. Taking Cilnilot-Trio Tablet may lower your blood pressure.

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Liver

Caution

Cilnilot-Trio Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Unsafe

Cilnilot-Trio Tablet is not recommended in children. The safety and efficacy of Cilnilot-Trio Tablet in children have not yet been established.

FAQs

Cilnilot-Trio Tablet is used to treat high blood pressure. It works by relaxing blood vessels, reducing the heart's workload and making the heart more efficient at pumping blood throughout the body. It also removes extra water and certain electrolytes from the body and efficiently reduces blood pressure.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shoot up at any time. If you have a persistent headache, please consult your doctor immediately.
Yes, Cilnilot-Trio Tablet is contraindicated in people with known allergy to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided in women who are in the second and third trimesters of their pregnancy.
Yes, Cilnilot-Trio Tablet can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Cilnilot-Trio Tablet . If you still feel excessively thirsty, please consult your doctor and advise for the best results of Cilnilot-Trio Tablet .
It is unlikely that Cilnilot-Trio Tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There is not enough evidence to say for certain. For the best advice, consult your doctor.
Yes, Cilnilot-Trio Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists, consult your doctor and do what is advised.
Yes, Cilnilot-Trio Tablet can cause an upset stomach. So, it is preferred to take Cilnilot-Trio Tablet with food to avoid it.
High blood pressure during pregnancy may cause eclampsia, which can be harmful to both baby and mother. Therefore, during pregnancy, you should have regular blood pressure monitoring.
Cilnilot-Trio Tablet , if stopped abruptly, can lead to withdrawal symptoms. So, before stopping Cilnilot-Trio Tablet , consult your doctor; your dose will be lowered gradually to avoid unpleasant side effects of Cilnilot-Trio Tablet .
Cilnilot-Trio Tablet and Cilacar 10 are medications used to treat high blood pressure (hypertension). Still, they differ in their composition and mechanism of action. Cilnilot-Trio Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone. Whereas Cilacar 10 contains Cilnidipine.
Cilnilot-Trio Tablet and Benlong 4 mg are medications used to treat high blood pressure (hypertension). Still, they differ in their active ingredients and mechanism of action. Cilnilot-Trio Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone. Whereas Benlong 4 mg contains Benidipine.
Cilnilot-Trio Tablet and Telma 40 are medications for treating high blood pressure (hypertension). Still, they differ in their composition and mechanism of action. Cilnilot-Trio Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone. Whereas Telma 40 contains Telmisartan.
Cilnilot-Trio Tablet and Ciplar tablet differ in their composition and mechanism of action. Cilnilot-Trio Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone, while the Ciplar tablet contains Propranolol.
Cilnilot-Trio Tablet is a combination of three medicines, namely Olmesartan medoxomil, Cilnidipine, and Chlorthalidone, which help lower raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the heart's blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone (diuretic) removes extra water and certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.
Common side effects of Cilnilot-Trio Tablet may include headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Most of these side effects of Cilnilot-Trio Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Cilnilot-Trio Tablet can start showing its effect within one hour of its oral intake. However, it may take a few days to show its full effect, and this may vary from person to person.
Yes, Cilnilot-Trio Tablet can generally be taken on an empty stomach. However, it's always best to follow your doctor's instructions or as mentioned on the medication label.
No, you should not take Cilnilot-Trio Tablet or any other prescription medication on your own. Cilnilot-Trio Tablet is a prescription medication used to treat high blood pressure. Consult with a healthcare professional before starting any new medication, including Cilnilot-Trio Tablet , is essential. They can diagnose your condition accurately and prescribe the correct dosage.
No, you should not drink alcohol while taking this medication. Alcohol can increase the risk of side effects, such as dizziness and lightheadedness.
No, you should not drink grapefruit juice while taking this medication. Grapefruit juice can interact with this medication and increase the risk of side effects.
Cilnilot-Trio Tablet may interact with certain medications. So, you should talk to your doctor before taking any over-the-counter medications, such as pain relievers or cold medications, while taking this medication.
Your doctor will monitor your blood pressure to evaluate if this medicine is effective. You may also experience less symptoms, such as headaches or dizziness.
The long-term effects of taking this medicine remain unclear. However, the majority of people who use this drug do not encounter any serious long-term negative effects.
Cilnilot-Trio Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone.
Cilnilot-Trio Tablet is not recommended in children. The safety and efficacy of Cilnilot-Trio Tablet in children have not yet been established.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Cilnilot-Trio Tablet is pregnancy risk category D medicine which may cause harm to the fetus or unborn baby. So, when pregnancy is detected, discontinue Cilnilot-Trio Tablet as soon as possible and consult the doctor.

Country of origin

India
Other Info - CIL0565

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