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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Betrecep 5 mg Tablet is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It contains Tofacitinib which works by lowering inflammation and symptoms associated with arthritis. In some cases, this medicine may cause side effects such as diarrhoea, headache, upper respiratory tract infection, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

TOFACITINIB-5MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Betrecep 5 mg Tablet

Betrecep 5 mg Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is an inflammatory condition of the joints, often associated with psoriasis. Ulcerative colitis is an inflammatory disease of the large intestine.
 
Betrecep 5 mg Tablet contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 
 
In some cases, you may experience common side-effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Betrecep 5 mg Tablet if you are pregnant or breastfeeding. Betrecep 5 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Betrecep 5 mg Tablet

Treatment of Rheumatoid arthritis, Psoriatic arthritis, Ulcerative colitis.

Directions for Use

Swallow Betrecep 5 mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Betrecep 5 mg Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Betrecep 5 mg Tablet works by blocking Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. Betrecep 5 mg Tablet is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

How Betrecep 5 mg Tablet Works

Betrecep 5 mg Tablet contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Betrecep 5 mg Tablet

  • Headache
  • Diarrhoea
  • Vomiting
  • Nausea
  • Upper respiratory tract infection
  • Cold
  • High blood pressure

What if I have taken an overdose of Betrecep 5 mg Tablet

Take Betrecep 5 mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Betrecep 5 mg Tablet if you are allergic to any of its components; if you have a severe infection, bloodstream infection, active tuberculosis, or if you have severe liver problems such as cirrhosis. Avoid taking Betrecep 5 mg Tablet if you are pregnant or breastfeeding. Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, or were in close contact with someone who has/had tuberculosis; chronic lung disease, liver problems, hepatitis B/C, cancer, are at a high risk of developing skin cancer, inflammation/ulcers of the large intestine, kidney problems, planning to get vaccinated, heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems. If your white blood cell count or red blood cell count is low, avoid taking Betrecep 5 mg Tablet . Betrecep 5 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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TofacitinibTrastuzumab
Severe
TofacitinibDacarbazine
Severe

Drug-Drug Interactions

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TofacitinibTrastuzumab
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Combining Trastuzumab with Betrecep 5 mg Tablet 14's can increase the risk of neutropenia.

How to manage the interaction:
Although there is a possible interaction between Trastuzumab and Betrecep 5 mg Tablet 14's, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibDacarbazine
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Dacarbazine with Betrecep 5 mg Tablet 14's may increase the risk of serious infection.

How to manage the interaction:
There may be a possibility of interaction between Dacarbazine and Betrecep 5 mg Tablet 14's, but it can be taken if prescribed by a doctor. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
TofacitinibVoclosporin
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Betrecep 5 mg Tablet 14's with Voclosporin may increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Betrecep 5 mg Tablet 14's and Voclosporin, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibHydrocortisone
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
The combined use of Betrecep 5 mg Tablet 14's and Hydrocortisone can increase the risk of infections and gastrointestinal bleeding or perforation.

How to manage the interaction:
Co-administration of Betrecep 5 mg Tablet 14's and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, severe abdominal pain, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TofacitinibCisplatin
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Betrecep 5 mg Tablet 14's with cisplatin may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Betrecep 5 mg Tablet 14's and Cisplatin, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibRitonavir
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Betrecep 5 mg Tablet 14's with ritonavir may increase the blood levels of Betrecep 5 mg Tablet 14's.

How to manage the interaction:
Although there is a possible interaction between Betrecep 5 mg Tablet 14's and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
TofacitinibPaclitaxel
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Betrecep 5 mg Tablet 14's with Paclitaxel may increase the risk of infection.

How to manage the interaction:
Although taking Paclitaxel and Betrecep 5 mg Tablet 14's together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
TofacitinibZidovudine
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Zidovudine with Betrecep 5 mg Tablet 14's may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Betrecep 5 mg Tablet 14's and Zidovudine, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
TofacitinibAtazanavir
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Betrecep 5 mg Tablet 14's with atazanavir may increase the blood levels of Betrecep 5 mg Tablet 14's. This may lead to cause severe infections.

How to manage the interaction:
Co-administration of Betrecep 5 mg Tablet 14's with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
TofacitinibClarithromycin
Severe
How does the drug interact with Betrecep 5 mg Tablet 14's:
Taking Clarithromycin may boost the blood levels of Betrecep 5 mg Tablet 14's, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Betrecep 5 mg Tablet 14's if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)

Betrecep 5 mg Tablet Substitute

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Alcohol

Caution

It is not known if alcohol interacts with Betrecep 5 mg Tablet , so please consult a doctor.

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Pregnancy

Unsafe

Betrecep 5 mg Tablet must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Betrecep 5 mg Tablet and for 4 weeks after discontinuation.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Betrecep 5 mg Tablet . Please consult a doctor if you have any concerns.

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Driving

Safe

Betrecep 5 mg Tablet generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Betrecep 5 mg Tablet is not recommended for patients with severe liver problems.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Betrecep 5 mg Tablet is not recommended for children below 18 years as safety and effectiveness were not established.

FAQs

Betrecep 5 mg Tablet is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
Betrecep 5 mg Tablet works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Hypertension/high blood pressure could be a side-effect of Betrecep 5 mg Tablet . Consult your doctor before taking Betrecep 5 mg Tablet if you have high blood pressure or if you are taking anti-hypertensive medicines.
Diarrhoea might be a side-effect of Betrecep 5 mg Tablet . Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Betrecep 5 mg Tablet might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Betrecep 5 mg Tablet if you are trying to become pregnant or if you have any concerns regarding this.
Betrecep 5 mg Tablet affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.
Betrecep 5 mg Tablet is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.
Betrecep 5 mg Tablet may increase the risk of cancer by changing the way the immune system works. Inform the doctor if you ever had any type of cancer.
Betrecep 5 mg Tablet may begin working within 2-8 weeks after starting the treatment.
Betrecep 5 mg Tablet should not be taken along with tocilizumab as it might increase the risk of infections. Before starting Betrecep 5 mg Tablet , inform the doctor if you are taking tocilizumab.
Prior to starting Betrecep 5 mg Tablet , active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests should be done.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
Other Info - BET0763

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