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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bepofly 180 Tablet is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Bepofly 180 Tablet

Bepofly 180 Tablet is used together with lifestyle changes and certain cholesterol-lowering medicines to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).

Bepofly 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

In some cases, Bepofly 180 Tablet may cause side effects such as anaemia, gout, and pain in the shoulders, arms or legs. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Bepofly 180 Tablet if you are pregnant or breastfeeding. Bepofly 180 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Inform the doctor regarding your health condition and medicines you are taking to rule out any possible side effects/interactions.

Uses of Bepofly 180 Tablet

Treatment of high cholesterol

Directions for Use

Take Bepofly 180 Tablet with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Bepofly 180 Tablet belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used in addition to the cholesterol-lowering diet in adult patients with primary hypercholesterolaemia (high cholesterol) or mixed dyslipidaemia (imbalance of lipids), which are conditions that cause a high cholesterol level in the blood. Bepofly 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

How Bepofly 180 Tablet Works

Bepofly 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bepofly 180 Tablet

  • Anaemia (low red blood cells)
  • Gout (increased levels of uric acid)
  • Pain in arms, legs, or shoulders
  • Muscle spasms

What if I have taken an overdose of Bepofly 180 Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Bepofly 180 Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Do not take Bepofly 180 Tablet if you are allergic to any of its components, if you are pregnant or breastfeeding. Inform the doctor if you have/had gout, severe kidney or liver problems, or tendon problems. Consult the doctor immediately if you become pregnant during treatment with Bepofly 180 Tablet . Seek medical attention if you experience symptoms of gout (tender joints, joint redness, severe foot pain, especially in the toe joint, warm joints, and swelling), tendon problems (pain, swelling, tears and inflammation of tendons), or tendon rupture (hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, or are unable to move the affected area or put weight on the affected area).

Drug-Drug Interactions

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Bempedoic acidGatifloxacin
Severe
Bempedoic acidTrovafloxacin
Severe

Drug-Drug Interactions

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Bempedoic acidGatifloxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and gatifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Gatifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor immediately. Avoid or limit exercising or using the impacted area. Do not discontinue any medications without a doctor's advice.
Bempedoic acidTrovafloxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and Trovafloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Trovafloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bepofly 180 Tablet 10's and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGemifloxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and Gemifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Gemifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidOfloxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and Ofloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Bepofly 180 Tablet 10's and Ofloxacin together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Exercising or using the injured area should also be avoided. Do not discontinue any medications without consulting a doctor.
Bempedoic acidFludrocortisone
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Taking Bepofly 180 Tablet 10's with Fludrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Fludrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation in joints, consult a doctor. Exercising or using the injured area should also be avoided Do not discontinue any medications without consulting a doctor.
Bempedoic acidCinoxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Cinoxacin with Bepofly 180 Tablet 10's can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Bepofly 180 Tablet 10's with Cinoxacin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you feel pain or swelling in joints, consult your doctor immediately. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidDexamethasone
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's with Dexamethasone can result in tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Dexamethasone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking Bepofly 180 Tablet 10's and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue the medication without consulting a doctor.
Bempedoic acidCortisone
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and Cortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Cortisone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of joints, consult a doctor. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGrepafloxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and Grepafloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Grepafloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidNorfloxacin
Severe
How does the drug interact with Bepofly 180 Tablet 10's:
Co-administration of Bepofly 180 Tablet 10's and norfloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet 10's can be taken with Norfloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bepofly 180 Tablet 10's and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption. 
  • Choose healthy fats and cut down on trans fats.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Bepofly 180 Tablet Substitute

Substitutes safety advice
  • Brillo 180 Tablet 10's

    23.67per tablet
  • Bempesta 180 mg Tablet 10's

    23.63per tablet
  • Bemdac 180 mg Tablet 10's

    26.10per tablet
  • Bemzire 180 Tablet 10's

    18.54per tablet
  • Bempify 180 Tablet 10's

    21.60per tablet
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Bepofly 180 Tablet . Please consult a doctor.

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Pregnancy

Unsafe

Bepofly 180 Tablet may harm the unborn baby. Do not take Bepofly 180 Tablet if you are pregnant, think you may be pregnant or if you are trying to become pregnant. Consult the doctor immediately if you become pregnant during treatment with Bepofly 180 Tablet .

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Breast Feeding

Unsafe

It is unknown if Bempedoic acid passes into breast milk. Do not take Bepofly 180 Tablet if you are breastfeeding.

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Driving

Safe

Bepofly 180 Tablet has little or no influence on your ability to drive.

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Liver

Caution

It is not known if Bepofly 180 Tablet is safe and effective in people with liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

It is not known if Bepofly 180 Tablet is safe and effective in people with kidney disease, including end-stage kidney disease, who are on dialysis. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Bepofly 180 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

FAQs

Bepofly 180 Tablet is used to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).
Bepofly 180 Tablet works by blocking the production of cholesterol in the liver. Thereby, it helps treat high cholesterol.
Do not discontinue Bepofly 180 Tablet without consulting your doctor, as it could lead to a rise in cholesterol. To get effective results, continue taking Bepofly 180 Tablet for as long as prescribed. Do not hesitate to speak with your doctor if you experience any difficulty while taking Bepofly 180 Tablet .
Tendon problems may happen in people taking Bepofly 180 Tablet . Consult the doctor if you experience pain, swelling, inflammation and tears of tendons, including Achilles (back of ankle), arm and shoulder. The risk of tendon problems may be increased if you are above 60 years of age, have renal problems, have had tendon problems or are taking antibiotics or corticosteroids.
Bepofly 180 Tablet can sometimes cause tiredness. Although it's not a common side effect, some people may feel fatigued while taking it. If you're experiencing this, talk to your doctor. They can help determine if it's related to the medication and recommend what to do.
Bepofly 180 Tablet can sometimes affect the liver. While it's generally safe, some people may have slightly elevated liver enzymes. These usually go back to normal on their own. If you notice any signs of liver problems, like yellowing of the skin or dark urine, talk to your doctor right away.
Your doctor may not prescribe Bepofly 180 Tablet if you have a history of tendon problems, severe liver problems, or if you're pregnant or breastfeeding. It can also interact with certain other medications. If you have any of these conditions, talk to your doctor before starting Bepofly 180 Tablet .
Take it with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.
LDL cholesterol is often called "bad cholesterol" because it can clog your arteries. This can make it harder for blood to reach your heart, increasing your risk of heart problems.
HDL cholesterol is often called "good cholesterol" because it helps clear out bad cholesterol. Higher levels of HDL can be good for your heart health. But it's important to manage both good and bad cholesterol for a healthy heart.
The only way to know whether you have high cholesterol is to get your cholesterol checked. Your health professional can do a simple blood test. This is called a lipid profile.
A healthy level of total cholesterol is below 5mmol/L. HDL (good cholesterol) is above 1.0mmol/L for men or above 1.2mmol/L for women. non-HDL (bad cholesterol) is below 4mmol/L.
High cholesterol can increase your risk of heart problems. It can build up in your arteries and cause problems like heart attacks. If you have symptoms like chest pain, shortness of breath, or fatigue, see a doctor. They can check your cholesterol and recommend treatment.
Lifestyle changes can help Bepofly 180 Tablet work better. Eat healthy, exercise regularly, maintain a healthy weight, quit smoking, limit alcohol, and manage stress. These changes can help lower your cholesterol and reduce your risk of heart problems.
No, you should not stop taking Bepofly 180 Tablet without consulting your doctor. High cholesterol is a chronic condition, and you may need to continue taking medication to maintain healthy cholesterol levels.
While Bepofly 180 Tablet is generally well-tolerated, some people may experience side effects such as muscle pain, joint pain, fatigue, or digestive issues. If you experience any adverse effects, talk to your doctor.
Yes, Bepofly 180 Tablet is generally safe for people with diabetes. However, it's important to monitor your blood sugar levels closely while taking this medication.
If you have mild to moderate kidney problems, you may still be able to take Bepofly 180 Tablet . However, it's important to discuss this with your doctor, as your dosage may need to be adjusted.
It typically takes 4-8 weeks for Bepofly 180 Tablet to start lowering cholesterol levels.
No, Bepofly 180 Tablet is not known to cause weight gain.
Yes, Bepofly 180 Tablet can be taken with other cholesterol-lowering medications if prescribed by the doctor.
You can lower your cholesterol by eating healthy, exercising, quitting smoking, and managing stress. Sometimes, you might also need medicine.
High cholesterol can be caused by many things, including age, family history, diet, lack of exercise, smoking, being overweight, and having conditions like diabetes or thyroid problems.
It depends on how risky you are of having heart problems. If you have a lot of things that can increase your risk, you might need to check it more often.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - BEP0069

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