Bemdiff 180 mg Tablet is used together with lifestyle changes and certain cholesterol-lowering medicines to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).

Bemdiff 180 mg Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

In some cases, Bemdiff 180 mg Tablet may cause side effects such as anaemia, gout, and pain in the shoulders, arms or legs. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Bemdiff 180 mg Tablet if you are pregnant or breastfeeding. Bemdiff 180 mg Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Inform the doctor regarding your health condition and medicines you are taking to rule out any possible side effects/interactions.

Bemdiff 180 mg Tablet belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used in addition to the cholesterol-lowering diet in adult patients with primary hypercholesterolaemia (high cholesterol) or mixed dyslipidaemia (imbalance of lipids), which are conditions that cause a high cholesterol level in the blood. Bemdiff 180 mg Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

• Anaemia (low red blood cells)
• Gout (increased levels of uric acid)
• Pain in arms, legs, or shoulders
• Muscle spasms

Do not take Bemdiff 180 mg Tablet if you are allergic to any of its components, if you are pregnant or breastfeeding. Inform the doctor if you have/had gout, severe kidney or liver problems, or tendon problems. Consult the doctor immediately if you become pregnant during treatment with Bemdiff 180 mg Tablet . Seek medical attention if you experience symptoms of gout (tender joints, joint redness, severe foot pain, especially in the toe joint, warm joints, and swelling), tendon problems (pain, swelling, tears and inflammation of tendons), or tendon rupture (hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, or are unable to move the affected area or put weight on the affected area).

Drug-Drug Interactions: Inform the doctor if you are taking statins (atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin), medicine used to treat pulmonary artery hypertension (bosentan), anti-hypertensive (fimasartan), or medicines used to treat hepatitis C (asunaprevir, glecaprevir, grazoprevir, voxilaprevir).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have gout/hyperuricemia (high uric acid levels), tendon problems, or severe kidney or liver problems.

• ATORVASTATIN
• FLUVASTATIN
• PITAVASTATIN
• PRAVASTATIN
• ROSUVASTATIN
• SIMVASTATIN
• BOSENTAN
• FIMASARTAN
• GLECAPREVIR
• GRAZOPREVIR
• VOXILAPREVIR

• Follow a cholesterol-lowering diet.
• Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
• Limit salt and sugar intake.
• Avoid smoking and alcohol consumption. 
• Choose healthy fats and cut down on trans fats.
• Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
• Get active by doing any physical activity such as swimming, brisk walking or jogging. Take stairs instead of elevators/lifts.

• Before starting the treatment, you should confirm you are not pregnant. Also, use effective contraception, as advised by your doctor during treatment with Bemdiff 180 mg Tablet .
• Bemdiff 180 mg Tablet treatment may increase liver enzyme levels. Your doctor may suggest tests to check your liver functioning while on treatment with this medicine.

High cholesterol: High cholesterol levels in the blood might build up on the walls of the arteries, leading to blockage of blood flow to the heart and other body parts, which could cause heart disease, heart attack or stroke. Cholesterol is mainly of two types, namely, 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG), which deposit fat in the arteries, leading to their blockage. Good cholesterol consists of high-density lipoprotein (HDL), which prevents the deposition of fats. Risk factors of high cholesterol are high-fat diet, obesity, lack of physical exercise, and smoking.