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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Benzz Injection is used to treat Non-Hodgkin's disease and Chronic Lymphocytic Leukaemia. Benzz Injection contains Bendamustine; it works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. This medication is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

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Prescription drug

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Synonym :

BENDAMUSTINE HYDROCHLORIDE

Composition :

BENDAMUSTINE-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Benzz Injection

Benzz Injection belongs to a class of anti-cancer medicines used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. This medicine is used in the treatment of Chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin’s leukemia (NHL) that has progressed during six months of treatment with rituximab or rituximab-containing treatment.

Benzz Injection contains Bendamustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

Benzz Injection may cause certain side effects, such as nausea, vomiting, diarrhea, stomach pain, anorexia, decreased weight, constipation, fever, decreased platelet count, fatigue, cough, headache, rash, injection site reactions and pain at the site of injection. If the side effects bother you, inform your doctor. A trained healthcare professional will administer Benzz Injection. Hence, do not self-administer.

Benzz Injection should be avoided if you are allergic to it or any other components present in it. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or any allergic conditions. Benzz Injection is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Benzz Injection

Treatment of Non-Hodgkin's disease and Chronic Lymphocytic Leukaemia

Medicinal Benefits

Benzz Injection contains Bendamustine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. This medicine is used in the treatment of chronic lymphocytic leukemia and non-Hodgkin’s leukemia.

Side Effects of Benzz Injection

  • Diarrhoea
  • Back pain
  • Vomiting
  • Stomach pain
  • Cough
  • Bruising or bleeding gums
  • Pain at the site of injection
  • Fever
  • Anorexia
  • Constipation
  • Decreased platelet count
  • Rashes
  • Decreased weight
  • Injection site reactions

Directions for Use

A trained healthcare professional will administer Benzz Injection. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Benzz Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before receiving this injection, inform your doctor if you have any history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or any allergic conditions. Benzz Injection may cause myelosuppression, active infections, severe skin reactions, tumor lysis syndrome (tumor cells release their contents into the bloodstream), other malignancies, and hypersensitivity reactions in some patients. Hence, careful monitoring should be done during the entire treatment. Benzz Injection may cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Before nursing, a breastfeeding mother should ask her oncologist whether this medicine is safe for use or not. Benzz Injection is not recommended for use in children as the safety and efficacy are not established.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

verifiedApollotooltip
BendamustineBaricitinib
Severe
BendamustineClozapine
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • After your treatment begins, dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

How Benzz Injection Works

Benzz Injection contains Bendamustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

What if I have taken an overdose of Benzz Injection

As Benzz Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Benzz Injection may cause rapid, irregular, or pounding heartbeat.
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Alcohol

Caution

Limit or avoid consumption of alcohol as it may worsen your condition.

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Pregnancy

Unsafe

Benzz Injection is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Benzz Injection. Use reliable methods of birth control while on treatment with Benzz Injection.

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Breast Feeding

Caution

If you are a nursing mother, inform your doctor before receiving Benzz Injection. You should not breastfeed while on treatment with Benzz Injection.

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Driving

Not applicable

-

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Benzz Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition. Benzz Injection is not recommended for use in patients with severe liver disease.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Benzz Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition. This medicine should be avoided for patients with CrCl <40 ml/min.

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Children

Unsafe

Benzz Injection is not recommended for use in children as the safety and efficacy is not established.

Country of origin

INDIA

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - BEN0206

Author Details

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Benzz Injection Substitute

Substitutes safety advice
  • BENDIT 100MG INJECTION

    2987.30per tablet
  • BIMODE 100MG INJECTION 20ML

    106.03per tablet
  • PURPLZ 100MG VIAL INJECTION

    3660.10per tablet
  • ZUMUSTIN 100MG INJECTION

    6350.90per tablet
  • Bizisa Injection 1's

    5740.00per tablet

FAQs

Benzz Injection is used to treat Non-Hodgkin’s disease and Chronic Lymphocytic Leukaemia.
Benzz Injection contains Bendamustine, which inhibits the DNA and RNA transcription essential for cancer cell growth.
Benzz Injection may cause reactivation of serious infections, myelosuppression, tumour lysis syndrome, and anaphylactic reactions in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.
Benzz Injection is safe when used as per the dose and duration advised by a doctor.
Benzz Injection has the vesicant (irritant) properties.
Yes, the use of Benzz Injection can cause hair loss and constipation as a side effect. This will gradually reduce over time and does not require any medical attention. However, please contact a doctor if this condition persists for longer or worsens.
Benzz Injection can cross the blood-brain barrier and can be utilized for treating cancers that have spread to the brain.
Benzz Injection may cause side effects such as diarrhoea, back pain, vomiting, stomach pain, cough, pain at the site of injection, fever, constipation, decreased blood pressure, rashes, and decreased weight. Please, contact a doctor if these side effects persist for longer durations.

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Keep Refrigerated. Do not freeze.

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