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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bactrim DS Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). It contains Trimethoprim and Sulfamethoxazole, which stop the growth of bacteria and kill them. Therefore, it helps treat bacterial infections. In some cases, you may experience specific common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bactrim DS Tablet

Bactrim DS Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. Bactrim DS Tablet does not work against infections caused by the virus, including cold and flu. 

Bactrim DS Tablet combines two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for forming proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Bactrim DS Tablet stops the growth of bacteria and kills them. Therefore, it helps treat bacterial infections.

Your doctor will decide the dose and duration of Bactrim DS Tablet based on your condition and the severity of the infection. In some cases, you may experience specific common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Bactrim DS Tablet , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Bactrim DS Tablet on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Bactrim DS Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Bactrim DS Tablet is not recommended for children below 12 years.

Uses of Bactrim DS Tablet

Bactrim DS Tablet is used to treat bacterial infections. The detailed uses of Bactrim DS Tablet are as follows:
•Urinary Tract Infections (UTIs): Bactrim DS Tablet is often utilized to treat urinary tract infections caused by susceptible bacteria. It prevents bacterial growth and allows the immune system to eliminate the disease.
•Respiratory Tract Infection: Bactrim DS Tablet can be used to treat specific respiratory infections, including bronchitis and pneumonia, and prevent breathing difficulties caused by bacterial infection.
•Gastrointestinal infections: Bactrim DS Tablet is often helpful against gastrointestinal infections, especially those caused by Shigella or Salmonella strains. It reduces symptoms like diarrhea and abdominal pain.
•Skin and Soft Tissue Infections: Bactrim DS Tablet effectively treats bacterial skin infections such as infected cuts, burns, or surgical wounds.
•Pneumocystis Pneumonia (PCP): Bactrim DS Tablet prevents a potentially life-threatening condition in those with weakened immune systems.

Directions for Use

Swallow Bactrim DS Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Bactrim DS Tablet belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bactrim DS Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Bactrim DS Tablet kills the bacteria and stops their growth. Therefore, it helps treat bacterial infections. Bactrim DS Tablet is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

How Bactrim DS Tablet Works

Bactrim DS Tablet is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Bactrim DS Tablet stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bactrim DS Tablet

  • High levels of potassium in the blood
  • Palpitations (abnormal heartbeats)
  • Thrush or candidiasis (fungal infection)
  • Headache
  • Nausea
  • Diarrhoea
  • Skin rashes

What if I have taken an overdose of Bactrim DS Tablet

Do not take more than the prescribed dose of Bactrim DS Tablet as it may cause overdose. The symptoms of overdose include headache, dizziness, nausea, vomiting, confusion, loss of appetite, drowsiness, or mental depression. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Bactrim DS Tablet if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Bactrim DS Tablet if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Bactrim DS Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
TrimethoprimBupivacaine
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Bactrim DS Tablet:
Taking Bactrim DS Tablet with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Bactrim DS Tablet and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimBupivacaine
Severe
How does the drug interact with Bactrim DS Tablet:
Taking Bupivacaine and Bactrim DS Tablet may cause methemoglobinemia, (blood disorder that affects how red blood cells deliver oxygen throughout the body).

How to manage the interaction:
Although there is an interaction between bupivacaine and Bactrim DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
TrimethoprimPotassium citrate
Severe
How does the drug interact with Bactrim DS Tablet:
Taking Potassium citrate with Bactrim DS Tablet may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Bactrim DS Tablet and Potassium citrate, you can take these medicines together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
TrimethoprimLevobupivacaine
Severe
How does the drug interact with Bactrim DS Tablet:
Taking Bactrim DS Tablet with Levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levobupivacaine and Bactrim DS Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimSpironolactone
Severe
How does the drug interact with Bactrim DS Tablet:
Taking spironolactone with Bactrim DS Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking spironolactone and Bactrim DS Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
TrimethoprimPotassium chloride
Severe
How does the drug interact with Bactrim DS Tablet:
Taking Potassium chloride with Bactrim DS Tablet may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood.).

How to manage the interaction:
Although there is a possible interaction between Bactrim DS Tablet and Potassium chloride, you can take these medicines together if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
TrimethoprimFosphenytoin
Severe
How does the drug interact with Bactrim DS Tablet:
Taking fosphenytoin with Bactrim DS Tablet may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between fosphenytoin and Bactrim DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience, weakness, vomiting, blurry vision, or trouble speaking. Do not discontinue any medications without consulting a doctor.
TrimethoprimValsartan
Severe
How does the drug interact with Bactrim DS Tablet:
Using Bactrim DS Tablet together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Bactrim DS Tablet together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
TrimethoprimLidocaine
Severe
How does the drug interact with Bactrim DS Tablet:
Taking Lidocaine with Bactrim DS Tablet may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Bactrim DS Tablet with Lidocaine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience, gray skin color, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimIvacaftor
Severe
How does the drug interact with Bactrim DS Tablet:
When Bactrim DS Tablet is taken with Ivacaftor, the amount of Bactrim DS Tablet in the blood increases.

How to manage the interaction:
Taking Bactrim DS Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Bactrim DS Tablet Substitute

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Alcohol

Unsafe

Avoid alcohol consumption while taking Bactrim DS Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Caution

Please consult your doctor before taking Bactrim DS Tablet if you are pregnant. Your doctor will prescribe Bactrim DS Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding, your doctor will prescribe Bactrim DS Tablet only if the benefits outweigh the risks.

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Driving

Caution

It is unknown whether Bactrim DS Tablet affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed.

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Liver

Caution

Please consult your doctor before taking Bactrim DS Tablet if you have liver impairment/liver disease. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

Bactrim DS Tablet to be taken with caution, especially if you have a history of kidney impairment/kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Bactrim DS Tablet is not recommended for children below 12 years.

FAQs

Bactrim DS Tablet is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).

Bactrim DS Tablet is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Bactrim DS Tablet kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.

Bactrim DS Tablet causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Bactrim DS Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Bactrim DS Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Bactrim DS Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Bactrim DS Tablet for as long as your doctor has prescribed to treat your condition effectually.

Do not take Bactrim DS Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Bactrim DS Tablet may affect certain laboratory test results. Inform the person doing the tests that you are taking Bactrim DS Tablet .

Bactrim DS Tablet may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Bactrim DS Tablet .

You can take Bactrim DS Tablet with or without as advised by your doctor. Take Bactrim DS Tablet preferably with food to avoid nausea or diarrhoea.

No, Bactrim DS Tablet is not an addiction causing medicine. But the dose and duration should be followed as prescribed by your doctor.

Yes, Bactrim DS Tablet can be used for urinary tract infection as Bactrim DS Tablet is used to prevent infections caused by bacteria.

Pimples are caused due to various reasons. Therefore, please consult your doctor before taking Bactrim DS Tablet . If you have any concerns regarding acne, discuss with your doctor.

Yes, Bactrim DS Tablet is a stronger antibiotic. It contains two antibiotics namely, Sulfamethoxazole and Trimethoprim.

Bactrim DS Tablet can cause side effects such as high levels of potassium in your blood, which can cause abnormal heart beats. Also, it may cause fungal infections like thrush or candidiasis which can affect mouth or vagina and other common side effects like headache, nausea, diarrhoea and skin rashes. If these effects worsen or persist, consult your doctor.

Yes, Bactrim DS Tablet is safe to use in most patients. However consult your doctor if you experience any side effects like nausea, vomiting, skin rash, allergic reaction.

Yes, Bactrim DS Tablet can cause nausea and vomiting. If these persist or worsen, consult your doctor.

Bactrim DS Tablet is contraindicated in patients who have a history of drug-induced immune thrombocytopenia from using trimethoprim and/or sulfonamides, who have a known hypersensitivity to these medications, or who have megaloblastic anemia from a folate deficiencies and in patients with severe renal insufficiency or obvious liver impairment.

Avoid spicy, acidic, and greasy foods while taking Bactrim DS Tablet as they may increase your risk of side effects such upset stomach and diarrhoea. Also, Bactrim DS Tablet can interact with alcohol. It's best to avoid drinking alcohol while taking Bactrim DS Tablet .

Yes, Bactrim DS Tablet expires. The expiry date can be found on the packaging.

No, do not stop taking Bactrim DS Tablet without first consulting your doctor. Complete the full course of treatment even if you feel better as you may notice an improvement in your symptoms before the infection is cured completely.

If you miss a dose of Bactrim DS Tablet , do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

If you don't feel better after completing the full course of treatment with Bactrim DS Tablet , inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Bactrim DS Tablet .

Bactrim DS Tablet should be used in children above 12 years of age if advised by a doctor.

Avoid taking Bactrim DS Tablet if you are allergic to Sulfamethoxazole, Trimethoprim or any other ingredients of Bactrim DS Tablet . If you have severe liver or kidney problems, or have ever had thrombocytopenia (blood problem causing bleeding or bruises) or have porphyria (a rare blood problem), inform your doctor before taking Bactrim DS Tablet .

Take Bactrim DS Tablet as advised by your doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose. Swallow it as whole with a glass of water. Do not crush or chew it.

Store the Bactrim DS Tablet in the original package at room temperature. Keep it out of the reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - BAC0009

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