Axepine 50mg Tablet is a second-generation tricyclic dibenzoxazepine antidepressant. It is used in the treatment of depression along with anxiety and agitation. Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the person's feelings, thinking and how they act. Anxiety is a mental condition characterized by excessive fear or worry affecting an individual's daily activities. This medicine is mostly given when patients become intolerant to other antidepressants.

Axepine 50mg Tablet contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

Axepine 50mg Tablet may cause certain common side effects such as drowsiness, dry mouth, increased heart rate, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and sudden blood pressure lowering on standing up (orthostatic hypotension). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Take Axepine 50mg Tablet as prescribed by your doctor. Your doctor will decide the dose of the medicine based on the severity of the condition.

Avoid taking Axepine 50mg Tablet if you are allergic to it or any of its ingredients. Axepine 50mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOs). Let your doctor know about your entire medical history beforehand. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding before starting treatment with Axepine 50mg Tablet . Do not stop taking Axepine 50mg Tablet suddenly, as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Axepine 50mg Tablet contains Amoxapine which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better. Axepine 50mg Tablet helps treat depression when patients become intolerant to other medicines.

• Drowsiness
• Dry mouth
• Increased heart rate
• Constipation
• Difficulty in urination
• Dizziness
• Headache
• Fatigue
• Weakness
• Excessive appetite
• Restlessness
• Nervousness
• Confusion
• Orthostatic hypotension (Sudden lowering of blood pressure on standing up)

Axepine 50mg Tablet should be avoided if you are allergic to it or any of its ingredients. Axepine 50mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOIs). Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting treatment with Axepine 50mg Tablet . Let your doctor know if you have liver or kidney disease, asthma, seizures, Parkinson’s disease, and high blood pressure before starting treatment with this medicine, as it may cause serious side effects. It is advised not to stop taking Axepine 50mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Drug-Drug Interactions: Axepine 50mg Tablet is known to interact with monoamine oxidase (MAO) inhibitors (e.g. isocarboxazid, phenelzine, selegiline, tranylcypromine), antipsychotics (e.g. chlorpromazine, fluphenazine, perphenazine, prochlorperazine, thioridazine, trifluoperazine, bupropion), medication to treat stomach ulcer (e.g. cimetidine), thyroid hormone, anti-diabetic medications (e.g. tolazamide), opioid pain or cough relievers (e.g. codeine, hydrocodone),  and drugs used for sleep or anxiety disorders (e.g. alprazolam, lorazepam, zolpidem).

Drug-Food Interactions: Axepine 50mg Tablet is known to interact with alcohol.

Drug-Disease Interactions: Axepine 50mg Tablet should not be given to patients with glaucoma (increased eye pressure), serious liver or kidney problem, asthma, or difficulty in urination.

• ISOCARBOXAZID
• PHENELZINE
• SELEGILINE
• CHLORPROMAZINE
• FLUPHENAZINE
• TRIFLUOPERAZINE
• BUPROPION
• CIMETIDINE
• TOLAZAMIDE
• CODEINE
• ALPRAZOLAM
• ZOLPIDEM

• Try to do regular exercise, which can help lower anxiety and improve your sleep and self-image.
• Find humour in your daily life. Try to watch a comedy show to help relieve stress.
• You can try increasing your mindfulness by including yoga, meditation, cognitive therapy, and mindfulness-based stress reduction.
• Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
• Include your diet with whole grains, vegetables, and fruits which is a healthier option than eating many simple carbohydrates in processed foods.
• Include herbs like turmeric, ginger, and chamomile in the meal. It can reduce inflammation caused due to anxiety disorder.
• Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake.
• Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

• Regular blood tests are required to monitor blood sugar and sodium level.
• Regular blood tests for monitoring various kinds of blood cells.
• Family members should monitor the patient for suicidal thoughts, unusual or withdrawal symptoms while taking Axepine 50mg Tablet .

Depression: Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the persons feeling, thinking and how they act.  The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions. It can influence some chronic health conditions and relationships. This condition is characterized by sadness, unhappiness, anger, hopelessness, etc.