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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

A Pine 50mg Tablet is used to treat depression, anxiety, and agitation. It contains Amoxapine, a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for mental health and mood changes. This medicine helps improve mood and feelings.

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Composition :

AMOXAPINE-50MG

Manufacturer/Marketer :

Psycogen Captab

Consume Type :

ORAL

Return Policy :

Not Returnable

About A Pine 50mg Tablet

A Pine 50mg Tablet is a second-generation tricyclic dibenzoxazepine antidepressant. It is used in the treatment of depression along with anxiety and agitation. Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the person's feelings, thinking and how they act. Anxiety is a mental condition characterized by excessive fear or worry affecting an individual's daily activities. This medicine is mostly given when patients become intolerant to other antidepressants.

A Pine 50mg Tablet contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

A Pine 50mg Tablet may cause certain common side effects such as drowsiness, dry mouth, increased heart rate, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and sudden blood pressure lowering on standing up (orthostatic hypotension). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Take A Pine 50mg Tablet as prescribed by your doctor. Your doctor will decide the dose of the medicine based on the severity of the condition.

Avoid taking A Pine 50mg Tablet if you are allergic to it or any of its ingredients. A Pine 50mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOs). Let your doctor know about your entire medical history beforehand. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding before starting treatment with A Pine 50mg Tablet. Do not stop taking A Pine 50mg Tablet suddenly, as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Uses of A Pine 50mg Tablet

Treatment of Depression

Directions for Use

Take A Pine 50mg Tablet as advised by the doctor. It can be taken with or without food. Swallow it as a whole with a glass of water. Do not crush, chew or break the medicine.

Medicinal Benefits

A Pine 50mg Tablet contains Amoxapine which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better. A Pine 50mg Tablet helps treat depression when patients become intolerant to other medicines.

How A Pine 50mg Tablet Works

A Pine 50mg Tablet contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

Storage

Store in a cool and dry place away from sunlight

Side Effects of A Pine 50mg Tablet

  • Drowsiness
  • Dry mouth
  • Increased heart rate
  • Constipation
  • Difficulty in urination
  • Dizziness
  • Headache
  • Fatigue
  • Weakness
  • Excessive appetite
  • Restlessness
  • Nervousness
  • Confusion
  • Orthostatic hypotension (Sudden lowering of blood pressure on standing up)

What if I have taken an overdose of A Pine 50mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of A Pine 50mg Tablet may include change in consciousness, drowsiness, epileptic seizure (that will not stop), fatigue, high blood pressure, increased thirst, loss of consciousness, swelling of face, fingers, or lower legs, total body jerking, troubled breathing, and weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

A Pine 50mg Tablet should be avoided if you are allergic to it or any of its ingredients. A Pine 50mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOIs). Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting treatment with A Pine 50mg Tablet. Let your doctor know if you have liver or kidney disease, asthma, seizures, Parkinson’s disease, and high blood pressure before starting treatment with this medicine, as it may cause serious side effects. It is advised not to stop taking A Pine 50mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Drug-Drug Interactions

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AmoxapineMetoclopramide
Critical
AmoxapineTranylcypromine
Critical

Drug-Drug Interactions

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AmoxapineMetoclopramide
Critical
How does the drug interact with A Pine 50mg Tablet:
Co-administration of Metoclopramide with A Pine 50mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with A Pine 50mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmoxapineTranylcypromine
Critical
How does the drug interact with A Pine 50mg Tablet:
Taking tranylcypromine with A Pine 50mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking A Pine 50mg Tablet with Tranylcypromine is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
AmoxapineSafinamide
Critical
How does the drug interact with A Pine 50mg Tablet:
Taking Safinamide with A Pine 50mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with A Pine 50mg Tablet is not recommended, as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
AmoxapineZiprasidone
Critical
How does the drug interact with A Pine 50mg Tablet:
Co-administration of A Pine 50mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and A Pine 50mg Tablet but can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmoxapineGatifloxacin
Severe
How does the drug interact with A Pine 50mg Tablet:
Taking Gatifloxacin and A Pine 50mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although taking Gatifloxacin and A Pine 50mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AmoxapineSotalol
Severe
How does the drug interact with A Pine 50mg Tablet:
Using Sotalol together with A Pine 50mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Sotalol with A Pine 50mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations Do not stop using any medications without consulting a doctor.
AmoxapineGalantamine
Severe
How does the drug interact with A Pine 50mg Tablet:
When A Pine 50mg Tablet and Galantamine are taken together, the body's ability to break down A Pine 50mg Tablet may be reduced. This increases A Pine 50mg Tablet levels and risk or severity of side effects.

How to manage the interaction:
Taking Galantamine with A Pine 50mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - memory problems, trouble with your nerves, feeling sleepy, feeling confused, or having difficulty thinking clearly, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmoxapineBupropion
Severe
How does the drug interact with A Pine 50mg Tablet:
Taking bupropion with A Pine 50mg Tablet may raise the chance of seizures(fits), which can happen with either medicine. Furthermore, bupropion can raise A Pine 50mg Tablet levels in the blood, which may exacerbate other adverse effects.

How to manage the interaction:
Co- administration of bupropion along with A Pine 50mg Tablet can possibly lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
AmoxapineClonidine
Severe
How does the drug interact with A Pine 50mg Tablet:
Co-administration of Clonidine and A Pine 50mg Tablet may increase the risk and severity of increased side effects.

How to manage the interaction:
Although there is a possible interaction between Clonidine and A Pine 50mg Tablet, you can take these medicines together if prescribed by a doctor. However, contact a doctor if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache, or heart palpitations. Do not discontinue the medication without consulting a doctor.
AmoxapineSertraline
Severe
How does the drug interact with A Pine 50mg Tablet:
Co-administration of A Pine 50mg Tablet and Sertraline together may increase the effects of A Pine 50mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Sertraline and A Pine 50mg Tablet, they can be taken together if a doctor has prescribed it. Contact a doctor immediately if experience such as dry mouth, blurred vision, constipation, confusion, poor muscle coordination, abdominal cramping, shivering, sweating, and high heart rate. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to do regular exercise, which can help lower anxiety and improve your sleep and self-image.
  • Find humour in your daily life. Try to watch a comedy show to help relieve stress.
  • You can try increasing your mindfulness by including yoga, meditation, cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include your diet with whole grains, vegetables, and fruits which is a healthier option than eating many simple carbohydrates in processed foods.
  • Include herbs like turmeric, ginger, and chamomile in the meal. It can reduce inflammation caused due to anxiety disorder.
  • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

A Pine 50mg Tablet Substitute

Substitutes safety advice
  • Amolox 50 Tablet 10's

    13.50per tablet
  • Auxadep-50 Tablet 10's

    17.10per tablet
  • Demo 50 mg Tablet 10's

    by AYUR

    5.27per tablet
  • Axepine 50mg Tablet 10's

    7.65per tablet
  • Demolox 50mg Tablet

    3.94per tablet
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Alcohol

Unsafe

Alcohol should be avoided while on treatment with A Pine 50mg Tablet as it can affect you much more and may make you feel more depressed.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy inform your doctor before taking A Pine 50mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before receiving A Pine 50mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

A Pine 50mg Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with A Pine 50mg Tablet.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking A Pine 50mg Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking A Pine 50mg Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

A Pine 50mg Tablet is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

FAQs

A Pine 50mg Tablet is used to treat Depression.
A Pine 50mg Tablet contains Amoxapine, which belongs to the tricyclic antidepressant class of medicine. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes.
It is always advised to take A Pine 50mg Tablet around the same time every day for better results. Do not take more than the prescribed dose.
No, it is advised not to stop taking A Pine 50mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.
A Pine 50mg Tablet may cause side effects such as drowsiness, dry mouth, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and orthostatic hypotension (sudden lowering of blood pressure on standing up ). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is not known how/if A Pine 50mg Tablet affects pregnancy or the newborn baby. Therefore, consult the doctor if you are pregnant, planning pregnancy or breastfeeding. Your doctor may prescribe this medicine if the benefits outweigh the risks.
A Pine 50mg Tablet may increase the risk of suicidal behaviour and thinking; hence, patients taking A Pine 50mg Tablet should be monitored for clinical worsening, suicidality, or unusual changes in behaviour. A Pine 50mg Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with A Pine 50mg Tablet. Alcohol should be avoided while on treatment with A Pine 50mg Tablet as it may cause increased drowsiness.

Country of origin

India
Other Info - AP62134

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