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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Avonza Tablet is used to treat HIV infection. It works by inhibiting enzymes which are necessary for the reproduction of the virus. In some cases, this medicine may cause side effects such as headache, dizziness, nausea, insomnia and fatigue. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Avonza Tablet

Avonza Tablet belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Avonza Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Avonza Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

You should take this medicine exactly as prescribed by the doctor. Avonza Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.

It is not recommended to take Avonza Tablet if you are allergic to any contents of it. Before taking Avonza Tablet , inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, Hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Avonza Tablet should not be given to children below 2 years of age. Avonza Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Avonza Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Avonza Tablet

Treatment of HIV infection.

Directions for Use

Swallow Avonza Tablet as a whole with water. Do not chew, crush or break it. Avonza Tablet is to be taken empty stomach.

Medicinal Benefits

Avonza Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Avonza Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

 

How Avonza Tablet Works

Avonza Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Avonza Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Avonza Tablet

  • Headache
  • Dizziness
  • Nausea
  • Insomnia (difficulty in sleeping)
  • Weakness
  • Depression
  • Cough
  • Diarrhoea
  • Impaired concentration
  • Abnormal dreams
  • Fatigue
  • Nasal congestion (stuffy nose)
  • Pain

What if I have taken an overdose of Avonza Tablet

Take Avonza Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, trouble concentrating, sleepiness, unusual dreams, hallucination, uncontrolled muscle movements or shaking, and difficulty falling or staying asleep. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is not recommended to take Avonza Tablet if you are allergic to any contents of it. Before taking Avonza Tablet , inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Avonza Tablet should not be given to children below 2 years of age. Avonza Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Avonza Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Avonza Tablet should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
Tenofovir disoproxilDidanosine
Critical

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Avonza Tablet 30'S:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Avonza Tablet 30'S is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Avonza Tablet 30'S:
Coadministration of Didanosine with Avonza Tablet 30'S can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Avonza Tablet 30'S is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Avonza Tablet 30'S:
Combining Avonza Tablet 30'S and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Avonza Tablet 30'S with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
EfavirenzVoriconazole
Critical
How does the drug interact with Avonza Tablet 30'S:
Coadministration of Voriconazole with Avonza Tablet 30'S can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Avonza Tablet 30'S can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Avonza Tablet 30'S:
When Avonza Tablet 30'S is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Avonza Tablet 30'S is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzCarbamazepine
Critical
How does the drug interact with Avonza Tablet 30'S:
Using carbamazepine together with Avonza Tablet 30'S may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Avonza Tablet 30'S with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzZiprasidone
Critical
How does the drug interact with Avonza Tablet 30'S:
Using ziprasidone together with Avonza Tablet 30'S can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Avonza Tablet 30'S with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
EfavirenzDienogest
Critical
How does the drug interact with Avonza Tablet 30'S:
When Avonza Tablet 30'S is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Avonza Tablet 30'S with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Avonza Tablet 30'S:
Taking Avonza Tablet 30'S with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Avonza Tablet 30'S with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzLomitapide
Critical
How does the drug interact with Avonza Tablet 30'S:
When Avonza Tablet 30'S is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Avonza Tablet 30'S with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly. Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Eating a diet high in vegetables, fruits, whole grains, and legumes.
  • Choosing lean, low-fat sources of protein.
  • Limiting sweets, soft drinks, and foods with added sugar.
  • Including proteins, carbohydrates, and a little good fat in all meals and snacks.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Avonza Tablet Substitute

Substitutes safety advice
  • Epelar 300mg/300mg/400mg Tablet

    84.24per tablet
  • Trilavir Mini Tablet

    59.97per tablet
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Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects.

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Pregnancy

Caution

Avonza Tablet is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this Avonza Tablet .

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Breast Feeding

Caution

Avonza Tablet is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

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Driving

Caution

Avonza Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Avonza Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Avonza Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Avonza Tablet is not recommended for use in children below 2 years. In children above 2 years of age, dose adjustments may be necessary.

FAQs

Avonza Tablet is used to treat HIV infection.
Avonza Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Avonza Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
Avonza Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.
Avonza Tablet may cause the weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
Avonza Tablet should not be stopped suddenly. Inform your doctor before stopping Avonza Tablet .
Avonza Tablet should be used with caution in liver diseases, kidney diseases, hypercholesterolemia, CNS disorders and lactic acidosis.

Country of origin

INDIA

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103
Other Info - AVO0042

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