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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Asviia 3750IU Injection 5 ml is used to treat acute lymphoblastic leukaemia (ALL). It is also used with other chemotherapy drugs to treat a specific type of ALL in people who have had allergic reactions to medications similar to Pegaspargase, such as asparaginase. It contains Pegaspargase, an enzyme that breaks down asparagine, an essential building block of proteins without which cells cannot survive. It lowers the asparagine levels in blood cancer cells and stops them from growing.

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Prescription drug

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Synonym :

PEG L ASPARAGINASE

Composition :

PEGASPARGASE-3750IU

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Asviia 3750IU Injection 5 ml

Asviia 3750IU Injection 5 ml is used in the treatment of acute lymphoblastic leukaemia (ALL). It is also used with other chemotherapy drugs to treat a certain type of ALL in people who have had allergic reactions to medications similar to pegaspargase, such as asparaginase.

Asviia 3750IU Injection 5 ml contains Pegaspargase, an enzyme that breaks down asparagine, an important building block of proteins without which cells cannot survive. Asviia 3750IU Injection 5 ml lowers the asparagine levels in blood cancer cells and stops the cancer cells from growing.

In some cases, Asviia 3750IU Injection 5 ml may cause side effects such as tiredness, dizziness, fever, nausea, vomiting, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with the doctor if any of the side effects persist or worsen.

Do not receive Asviia 3750IU Injection 5 ml if you are pregnant or breastfeeding. Avoid driving or using machines as Asviia 3750IU Injection 5 ml may cause drowsiness, tiredness, and confusion. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Asviia 3750IU Injection 5 ml

Treatment of Acute lymphoblastic leukaemia (ALL)

Medicinal Benefits

Asviia 3750IU Injection 5 ml is used to treat acute lymphoblastic leukaemia (ALL). It is also used with other chemotherapy drugs to treat a certain type of ALL in people who have had allergic reactions to medications similar to pegaspargase, such as asparaginase. Asviia 3750IU Injection 5 ml contains Pegaspargase, an enzyme that breaks down asparagine, an important building block of proteins without which cells cannot survive. Normal cells can make asparagine for themselves, while some cancer cells cannot. Asviia 3750IU Injection 5 ml lowers asparagine levels in blood cancer cells and stops the cancer cells from growing.

Side Effects of Asviia 3750IU Injection 5 ml

  • Nausea
  • Vomiting
  • Fever
  • Diarrhoea
  • Tiredness
  • Dizziness

Directions for Use

Asviia 3750IU Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Asviia 3750IU Injection 5 ml if you are allergic to any of its components if you have severe liver disease, pancreatitis (inflammation of the pancreas) or if you have ever had severe bleeding or blood clots following asparaginase therapy. Inform the doctor if you have had serious allergic reactions to other forms of asparaginase, if you suffer from a bleeding disorder or have had serious blood clots, if you get a fever if you have poor liver function, diabetes, stroke or abdominal pain. Seek medical attention if you experience symptoms of osteonecrosis (pain in the knee, back or hip), liver or pancreas problems (loss of appetite, upper stomach pain, nausea or vomiting, fast heart rate, dark urine, or yellowing of the skin or eyes), low blood cell count (fever, mouth sores, skin sores, sore throat, cough, trouble breathing), blood clot (sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg), high blood sugar (increased thirst, increased urination, dry mouth, fruity breath odour) or if you notice unusual bleeding, easy bruising, or purple/red spot under the skin.

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

verifiedApollotooltip
PegaspargaseClozapine
Severe
PegaspargaseInfliximab
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

How Asviia 3750IU Injection 5 ml Works

Asviia 3750IU Injection 5 ml contains Pegaspargase, an enzyme that breaks down asparagine, an important building block of proteins without which cells cannot survive. Asviia 3750IU Injection 5 ml lowers the asparagine levels in blood cancer cells and stops the cancer cells from growing.

What if I have taken an overdose of Asviia 3750IU Injection 5 ml

As Asviia 3750IU Injection 5 ml is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.
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Alcohol

Caution

Please consult your doctor before consuming alcohol while on treatment with Asviia 3750IU Injection 5 ml as it may increase the risk of side effects such as liver damage.

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Pregnancy

Caution

Pegaspargase belongs to pregnancy category C. The effects of Asviia 3750IU Injection 5 ml during pregnancy have not been studied. If you are pregnant, planning for pregnancy or think you may be pregnant, talk to the doctor for advice.

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Breast Feeding

Unsafe

It is not known if Pegaspargase passes into breast milk. As a precautionary measure, breastfeeding should be discontinued during treatment and should not be re-started until after treatment with Asviia 3750IU Injection 5 ml has been discontinued.

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Driving

Caution

Do not drive or operate machinery as Asviia 3750IU Injection 5 ml may cause tiredness, confusion, and drowsiness.

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Liver

Caution

Asviia 3750IU Injection 5 ml is not recommended if you have severe liver disease. If you have a history of liver disease, inform your doctor before receiving Asviia 3750IU Injection 5 ml.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Asviia 3750IU Injection 5 ml.

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Children

Safe if prescribed

Asviia 3750IU Injection 5 ml is safe for use in children if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - ASV0007

Author Details

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FAQs

Asviia 3750IU Injection 5 ml is used to treat Acute lymphoblastic leukaemia (ALL).
Asviia 3750IU Injection 5 ml works by killing or stopping the growth of cancer cells.
If anticoagulants are used at the same time as Asviia 3750IU Injection 5 ml, there may be a higher risk of bleeding disorders. Therefore, consult the doctor if you are taking anticoagulant/blood thinner medicines.
Oral contraceptive is not an effective method of contraception whilst on treatment with Asviia 3750IU Injection 5 ml. Ask your doctor about the best contraceptive to use.
Asviia 3750IU Injection 5 ml may cause osteonecrosis (bone damage), especially when taken concomitantly with glucocorticoids. If you experience any new bone pain, like pain in the hip, back or knee, inform the doctor as soon as possible.
Consult the doctor if you are undergoing immunisation with live vaccines within 3 months of completing the treatment, as it may increase the risk of severe infections.
Asviia 3750IU Injection 5 ml can lead to fluctuations in clotting factors and may increase the risk of bleeding and/or clotting. If you notice unusual bleeding or bruising, consult the doctor.

Disclaimer

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