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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Apxenta 20mg Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. It contains Apremilast, which blocks the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis and psoriasis and thus, lowers the signs and symptoms of these conditions.
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Composition :

APREMILAST-20MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Apxenta 20mg Tablet

Apxenta 20mg Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Apxenta 20mg Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Apxenta 20mg Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Take Apxenta 20mg Tablet as prescribed by your doctor. You are advised to take Apxenta 20mg Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Apxenta 20mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Apxenta 20mg Tablet should not be taken in conditions like depression as it is getting worse with thoughts of suicide. Before starting Apxenta 20mg Tablet , please inform your doctor if you have any allergy to Apxenta 20mg Tablet and its parts. Apxenta 20mg Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Apxenta 20mg Tablet . Apxenta 20mg Tablet does not affect the ability to drive and use machines.

Uses of Apxenta 20mg Tablet

Treatment of Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Directions for Use

Take Apxenta 20mg Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Apxenta 20mg Tablet with or without food. Swallow the Apxenta 20mg Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Apxenta 20mg Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Apxenta 20mg Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

How Apxenta 20mg Tablet Works

Apxenta 20mg Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Apxenta 20mg Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Apxenta 20mg Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

What if I have taken an overdose of Apxenta 20mg Tablet

Do not take more than the prescribed dose of Apxenta 20mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor before using Apxenta 20mg Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Apxenta 20mg Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Apxenta 20mg Tablet if you have severe kidney problems. Inform your doctor while taking Apxenta 20mg Tablet if you lose weight without meaning to. Apxenta 20mg Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Apxenta 20mg Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Apxenta 20mg Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Apxenta 20mg Tablet .

 

Drug-Drug Interactions

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ApremilastPhenytoin
Severe
ApremilastPrimidone
Severe

Drug-Drug Interactions

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ApremilastPhenytoin
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of Phenytoin with Apxenta 20mg Tablet 10's may reduce the blood levels of Apxenta 20mg Tablet 10's, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Apxenta 20mg Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ApremilastPrimidone
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of Apxenta 20mg Tablet 10's with primidone may decrease the blood levels of Apxenta 20mg Tablet 10's, which may make Apxenta 20mg Tablet 10's less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Apxenta 20mg Tablet 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApremilastCarbamazepine
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Taking Apxenta 20mg Tablet 10's with carbamazepine can significantly reduce the blood levels of Apxenta 20mg Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Taking Apxenta 20mg Tablet 10's with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Rifapentine may decrease the blood levels of Apxenta 20mg Tablet 10's, which may make Apxenta 20mg Tablet 10's less effective in treating the condition.

How to manage the interaction:
Although taking Apxenta 20mg Tablet 10's and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ApremilastNevirapine
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of Nevirapine with Apxenta 20mg Tablet 10's may decrease the blood levels of Apxenta 20mg Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Apxenta 20mg Tablet 10's and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastRifampicin
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Taking Apxenta 20mg Tablet 10's with rifampicin can decrease the blood levels of Apxenta 20mg Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Apxenta 20mg Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastPhenobarbital
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of phenobarbital with Apxenta 20mg Tablet 10's can drastically lower Apxenta 20mg Tablet 10's levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking phenobarbital with Apxenta 20mg Tablet 10's can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastFosphenytoin
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of Fosphenytoin with Apxenta 20mg Tablet 10's may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Apxenta 20mg Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
ApremilastEnzalutamide
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of Enzalutamide with Apxenta 20mg Tablet 10's may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Apxenta 20mg Tablet 10's and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastMitotane
Severe
How does the drug interact with Apxenta 20mg Tablet 10's:
Coadministration of Mitotane with Apxenta 20mg Tablet 10's may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Apxenta 20mg Tablet 10's and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIPSORIATICS

Apxenta 20mg Tablet Substitute

Substitutes safety advice
  • Aprezo 20 Tablet 4's

    by AYUR

    25.88per tablet
  • Apraize-20 Tablet 4's

    27.23per tablet
  • Atlast 20 Tablet 10's

    17.10per tablet
  • Apraize-20 Tablet 10's

    by AYUR

    26.10per tablet
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Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Apxenta 20mg Tablet . Consult your doctor if you become pregnant while taking Apxenta 20mg Tablet .

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Breast Feeding

Caution

It is not known whether Apxenta 20mg Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Apxenta 20mg Tablet .

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Driving

Safe if prescribed

Apxenta 20mg Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Apxenta 20mg Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Apxenta 20mg Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Apxenta 20mg Tablet is not recommended for use in children and adolescents below 17 years.

FAQs

Apxenta 20mg Tablet is used to treat plaque psoriasis (scaly, itchy, and red patches on the skin), psoriatic arthritis (inflammation in the joints in people with psoriasis), and oral ulcers caused by Behcet's disease.
Apxenta 20mg Tablet works by blocking the action of some chemical messengers that are responsible for inflammation.
Yes, Apxenta 20mg Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Apxenta 20mg Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.
Apxenta 20mg Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.
Yes, Apxenta 20mg Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Apxenta 20mg Tablet . In case of big weight loss, inform your doctor. Your doctor may consider stopping Apxenta 20mg Tablet .
Rifampicin is an antibiotic. You should not take rifampicin if you are taking Apxenta 20mg Tablet . Rifampicin interferes with the working of Apxenta 20mg Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Apxenta 20mg Tablet .
As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.
No, Apxenta 20mg Tablet is not an immunosuppressant. It belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors which work by blocking the action of PDE4 that is found in inflammatory cells.
Take Apxenta 20mg Tablet as advised by the doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
If you get pregnant during treatment with Apxenta 20mg Tablet , inform your doctor immediately. You are recommended to avoid pregnancy during treatment with Apxenta 20mg Tablet as it may harm unborn baby.
Apxenta 20mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, back pain or weight loss. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - APX0006

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