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  3. Apxenta 10 Tablet 10's

Apxenta 10 Tablet 10's, Pack of 10 TabletS
Apxenta 10 Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Apxenta 10 Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. It contains Apremilast, which blocks the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis and psoriasis and thus, lowers the signs and symptoms of these conditions.
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Composition :

APREMILAST-10MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Apxenta 10 Tablet

Apxenta 10 Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Apxenta 10 Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Apxenta 10 Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Take Apxenta 10 Tablet as prescribed by your doctor. You are advised to take Apxenta 10 Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Apxenta 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Apxenta 10 Tablet should not be taken in conditions like depression as it is getting worse with thoughts of suicide. Before starting Apxenta 10 Tablet , please inform your doctor if you have any allergy to Apxenta 10 Tablet and its parts. Apxenta 10 Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Apxenta 10 Tablet . Apxenta 10 Tablet does not affect the ability to drive and use machines.

Uses of Apxenta 10 Tablet

Treatment of Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Directions for Use

Take Apxenta 10 Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Apxenta 10 Tablet with or without food. Swallow the Apxenta 10 Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Apxenta 10 Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Apxenta 10 Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

How Apxenta 10 Tablet Works

Apxenta 10 Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Apxenta 10 Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Apxenta 10 Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

What if I have taken an overdose of Apxenta 10 Tablet

Do not take more than the prescribed dose of Apxenta 10 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor before using Apxenta 10 Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Apxenta 10 Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Apxenta 10 Tablet if you have severe kidney problems. Inform your doctor while taking Apxenta 10 Tablet if you lose weight without meaning to. Apxenta 10 Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Apxenta 10 Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Apxenta 10 Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Apxenta 10 Tablet .

 

Drug-Drug Interactions

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ApremilastMitotane
Severe
ApremilastRifampicin
Severe

Drug-Drug Interactions

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ApremilastMitotane
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of Mitotane with Apxenta 10 Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Apxenta 10 Tablet and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastRifampicin
Severe
How does the drug interact with Apxenta 10 Tablet:
Taking Apxenta 10 Tablet with rifampicin can decrease the blood levels of Apxenta 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Apxenta 10 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastNevirapine
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of Nevirapine with Apxenta 10 Tablet may decrease the blood levels of Apxenta 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Apxenta 10 Tablet and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastCarbamazepine
Severe
How does the drug interact with Apxenta 10 Tablet:
Taking Apxenta 10 Tablet with carbamazepine can significantly reduce the blood levels of Apxenta 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Apxenta 10 Tablet with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ApremilastPhenobarbital
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of phenobarbital with Apxenta 10 Tablet can drastically lower Apxenta 10 Tablet levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking phenobarbital with Apxenta 10 Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastPrimidone
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of Apxenta 10 Tablet with primidone may decrease the blood levels of Apxenta 10 Tablet, which may make Apxenta 10 Tablet less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Apxenta 10 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Apxenta 10 Tablet:
Rifapentine may decrease the blood levels of Apxenta 10 Tablet, which may make Apxenta 10 Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Apxenta 10 Tablet and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ApremilastFosphenytoin
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of Fosphenytoin with Apxenta 10 Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Apxenta 10 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
ApremilastPhenytoin
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of Phenytoin with Apxenta 10 Tablet may reduce the blood levels of Apxenta 10 Tablet, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Apxenta 10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ApremilastEnzalutamide
Severe
How does the drug interact with Apxenta 10 Tablet:
Coadministration of Enzalutamide with Apxenta 10 Tablet may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Apxenta 10 Tablet and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIPSORIATICS

Apxenta 10 Tablet Substitute

Substitutes safety advice

  • Aprezo 10 Tablet 4's

    by AYUR

    ₹23.40per tablet

  • Atlast 10 Tablet 10's

    by Others

    ₹13.50per tablet

  • Aplex Kit (10Mg+20Mg+30Mg) Tablet 13'S

    by AYUR

    ₹13.50per tablet

  • Pd-Pill-10 Tablet 10's

    by Others

    ₹13.50per tablet

Product Substitutes

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Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Apxenta 10 Tablet . Consult your doctor if you become pregnant while taking Apxenta 10 Tablet .

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Breast Feeding

Caution

It is not known whether Apxenta 10 Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Apxenta 10 Tablet .

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Driving

Safe if prescribed

Apxenta 10 Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Apxenta 10 Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Apxenta 10 Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Apxenta 10 Tablet is not recommended for use in children and adolescents below 17 years.

FAQs

Apxenta 10 Tablet is used to treat plaque psoriasis (scaly, itchy, and red patches on the skin), psoriatic arthritis (inflammation in the joints in people with psoriasis), and oral ulcers caused by Behcet's disease.

Apxenta 10 Tablet works by blocking the action of some chemical messengers that are responsible for inflammation.

Yes, Apxenta 10 Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Apxenta 10 Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.

Apxenta 10 Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.

Yes, Apxenta 10 Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Apxenta 10 Tablet . In case of big weight loss, inform your doctor. Your doctor may consider stopping Apxenta 10 Tablet .

Rifampicin is an antibiotic. You should not take rifampicin if you are taking Apxenta 10 Tablet . Rifampicin interferes with the working of Apxenta 10 Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Apxenta 10 Tablet .

As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.

No, Apxenta 10 Tablet is not an immunosuppressant. It belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors which work by blocking the action of PDE4 that is found in inflammatory cells.

Take Apxenta 10 Tablet as advised by the doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.

If you get pregnant during treatment with Apxenta 10 Tablet , inform your doctor immediately. You are recommended to avoid pregnancy during treatment with Apxenta 10 Tablet as it may harm unborn baby.

Apxenta 10 Tablet may cause side effects such as nausea, vomiting, diarrhoea, back pain or weight loss. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - APX0007

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Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3648.pdf
  2. https://www.drugs.com/cdi/apremilast.html
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