apollo
0
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:36 PM IST
Aprezo 10 Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. It contains Apremilast, which blocks the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis and psoriasis and thus, lowers the signs and symptoms of these conditions.
Read more
77 people bought
in last 7 days
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition

APREMILAST-10MG

Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Aprezo 10 Tablet

Aprezo 10 Tablet is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Aprezo 10 Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Aprezo 10 Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin) and, thus, lower the signs and symptoms of these conditions.

Take Aprezo 10 Tablet as prescribed by your doctor. You are advised to take Aprezo 10 Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Aprezo 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Aprezo 10 Tablet should not be taken in conditions like depression as it is getting worse with thoughts of suicide. Before starting Aprezo 10 Tablet, please inform your doctor if you have any allergy to Aprezo 10 Tablet and its parts. Aprezo 10 Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Aprezo 10 Tablet. Aprezo 10 Tablet does not affect the ability to drive and use machines.

Uses of Aprezo 10 Tablet

Treatment of Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Medicinal Benefits

Aprezo 10 Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Aprezo 10 Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

Directions for Use

Take Aprezo 10 Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Aprezo 10 Tablet with or without food. Swallow the Aprezo 10 Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aprezo 10 Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

Drug Warnings

Inform your doctor before using Aprezo 10 Tablet, if you have previously had an allergic reaction (hypersensitivity). Before starting Aprezo 10 Tablet, please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Aprezo 10 Tablet if you have severe kidney problems. Inform your doctor while taking Aprezo 10 Tablet if you lose weight without meaning to. Aprezo 10 Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Aprezo 10 Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Aprezo 10 Tablet. Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Aprezo 10 Tablet.

 

Drug Interactions

Drug-Drug Interactions: Aprezo 10 Tablet may interact with medicines used for tuberculosis- TB (rifampicin), and medicines used in fit/epilepsy (phenytoin, phenobarbital, carbamazepine).

Drug-Food Interactions: No food interactions were found.

Drug-Disease Interactions: Aprezo 10 Tablet should not be given to patients with depression, kidney disease, and weight loss.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Special Advise

  • Aprezo 10 Tablet is a well-tolerated medicine. Mild stomach upset may arise early during the treatment.
  • Monitor your weight repeatedly as Aprezo 10 Tablet may lead to weight loss.
  • Inform your doctor immediately if you experience new or worsened depression, suicidal thoughts, unexplained weight loss, or other mood changes.

Disease/Condition Glossary

Plaque Psoriasis: It is an inflammatory disease of the skin, leading to red, scaly, thick, itchy, painful patches on your skin and can also affect your nails and scalp. It can happen at any age and is most common in 50 to 69. Internal and external activities, including sunburn, mild trauma, systemic drugs, infections, and stress, can also cause psoriasis.

Psoriatic arthritis: Psoriatic arthritis is an inflammatory disorder of the joints, which affects a few people who have skin from psoriasis.

Behçet’s disease: It is an uncommon type of inflammatory illness that affects many parts of the body. The most common difficulty is mouth ulcers. It is a disease that results in blood vessel swelling in the body.

bannner image

Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

bannner image

Pregnancy

Caution

If you are pregnant, inform your doctor before taking Aprezo 10 Tablet. Consult your doctor if you become pregnant while taking Aprezo 10 Tablet.

bannner image

Breast Feeding

Caution

It is not known whether Aprezo 10 Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Aprezo 10 Tablet.

bannner image

Driving

Safe if prescribed

Aprezo 10 Tablet has no or negligible influence on the ability to drive and use machines.

bannner image

Liver

Caution

Aprezo 10 Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

bannner image

Kidney

Caution

Aprezo 10 Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

bannner image

Children

Unsafe

Aprezo 10 Tablet is not recommended for use in children and adolescents below 17 years.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - APR0135

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Aprezo 10 Tablet is used to treat plaque psoriasis (scaly, itchy, and red patches on the skin), psoriatic arthritis (inflammation in the joints in people with psoriasis), and oral ulcers caused by Behcet's disease.
Aprezo 10 Tablet works by blocking the action of some chemical messengers that are responsible for inflammation.
Yes, Aprezo 10 Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Aprezo 10 Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.
Aprezo 10 Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.
Yes, Aprezo 10 Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Aprezo 10 Tablet. In case of big weight loss, inform your doctor. Your doctor may consider stopping Aprezo 10 Tablet.
Rifampicin is an antibiotic. You should not take rifampicin if you are taking Aprezo 10 Tablet. Rifampicin interferes with the working of Aprezo 10 Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Aprezo 10 Tablet.
As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.
No, Aprezo 10 Tablet is not an immunosuppressant. It belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors which work by blocking the action of PDE4 that is found in inflammatory cells.
Take Aprezo 10 Tablet as advised by the doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
If you get pregnant during treatment with Aprezo 10 Tablet, inform your doctor immediately. You are recommended to avoid pregnancy during treatment with Aprezo 10 Tablet as it may harm unborn baby.
Aprezo 10 Tablet may cause side effects such as nausea, vomiting, diarrhoea, back pain or weight loss. If these side effects persist or worsen, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Recommended for a 30-day course: 8 Strips

Add 8 Strips