Apronin 500000IU Injection belongs to the group of medicines called anti-fibrinolytic agents used to reduce bleeding during and after heart surgery. It is also used to lower the need for blood transfusion during and after heart surgery.

Apronin 500000IU Injection contains aprotinin that prevents bleeding by inhibiting the activation of coagulants.

Apronin 500000IU Injection will be administered by a healthcare professional; do not self-administer. In some cases, Apronin 500000IU Injection may cause chest pain, stomach upset, fast heartbeat and injection site reactions. You are advised to talk to the doctor if you experience any side effects.

Consult the doctor if you are pregnant or breastfeeding. Apronin 500000IU Injection is not recommended for children below 18 years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Apronin 500000IU Injection contains aprotinin that belongs to the group of medicines called anti-fibrinolytic agents used to reduce bleeding during and after heart surgery. It also lowers the need for blood transfusion during and after heart surgery. Apronin 500000IU Injection inhibits the activation of coagulants. Thereby, Apronin 500000IU Injection prevents bleeding.

• Chest pain
• Fast heartbeat
• Stomach upset
• Pain and irritation at the site of administration

Do not use Apronin 500000IU Injection if you are allergic to any of its components or if a positive aprotinin-specific IgG antibody test is available, indicating an increased risk of an allergic reaction to aprotinin. Inform the doctor if you have kidney problems or have/suspect you have received aprotinin or aprotinin-containing fibrin sealants in the last 12 months. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you have any health condition or if you are taking any medications, including herbal products or vitamin/mineral supplements.

Drug-Drug Interactions: Inform the doctor if you take medicines used to dissolve blood clots (streptokinase, urokinase, alteplase) or antibiotics (aminoglycosides).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have kidney problems.

• STREPTOKINASE
• UROKINASE
• ALTEPLASE

• Eat a diet rich in whole grains, vegetables, and fruits.
• Cut down on saturated fats, added sugars and salts.
• Manage stress with meditation and yoga.
• Avoid junk food and fast food.
• Follow a low-fat, low-cholesterol, high-fiber diet.

Apronin 500000IU Injection may affect certain lab tests. If you are undergoing any lab tests, inform the doctor that you are on treatment with Apronin 500000IU Injection.

Perioperative blood management: It is a process to stop or prevent bleeding during surgery and avoid or minimise blood transfusion.