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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 9:32 AM IST

Apregen 150mg Injection is used to treat Chemotherapy-induced nausea and vomiting. It contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

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Composition :

FOSAPREPITANT-150MG

Manufacturer/Marketer :

Cellgen Biopharma

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Apregen 150mg Injection

Apregen 150mg Injection belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines). Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apregen 150mg Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Apregen 150mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Apregen 150mg Injection may cause common side effects such as headache, hiccups, tiredness, loss of appetite, indigestion, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately. 

If you are allergic to Fosaprepitant or other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Apregen 150mg Injection. Drive only if you are alert after receiving Apregen 150mg Injection. If you are taking other prescription or non-prescription medicines, inform your doctor before receiving Apregen 150mg Injection.

Uses of Apregen 150mg Injection

Treatment of Chemotherapy-induced nausea and vomiting

Medicinal Benefits

Apregen 150mg Injection contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Side Effects of Apregen 150mg Injection

  • Headache
  • Hiccups
  • Tiredness
  • Loss of appetite
  • Indigestion
  • Constipation

Directions for Use

Apregen 150mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Fosaprepitant or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Apregen 150mg Injection. Drive only if you are alert after receiving Apregen 150mg Injection. If you are taking any other prescription or non-prescription medicines, inform your doctor before receiving Apregen 150mg Injection. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Apregen 150mg Injection to check your blood clotting.

Therapeutic Class

ANTIEMETICS

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

How Apregen 150mg Injection Works

Apregen 150mg Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.

What if I have taken an overdose of Apregen 150mg Injection

As Apregen 150mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Consult your doctor

The interaction of alcohol with Apregen 150mg Injection is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Apregen 150mg Injection. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Fosaprepitant is excreted in breast milk. Hence, if you are a nursing mother, discuss with your doctor about the best way to feed your baby if you receive Apregen 150mg Injection.

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Driving

Caution

Apregen 150mg Injection may cause dizziness or sleepiness in some people. Therefore, if you feel dizzy or sleepy after receiving Apregen 150mg Injection, avoid driving or operating machinery.

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Liver

Caution

If you have liver disease, inform your doctor before receiving Apregen 150mg Injection.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before receiving Apregen 150mg Injection.

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Children

Caution

If you have any concerns regarding the use of Apregen 150mg Injection in children, please consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Sf-1, Ii-Floor, Rishabh Ipex Mall, Ip Extension, Patparganj, New Delhi- 110092
Other Info - AP42810

Author Details

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FAQs

Apregen 150mg Injection is used to treat Chemotherapy-induced nausea and vomiting.
Apregen 150mg Injection works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.
Apregen 150mg Injection may cause constipation as a common side effect. However, if the condition persists or worsens, please consult your doctor.
You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain intrauterine devices (IUDs) as they may not work properly when taken together with Apregen 150mg Injection. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apregen 150mg Injection and for up to 1 month after using Apregen 150mg Injection.

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