Apregen-150 Injection 1's
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Apregen-150 Injection 1's belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines). Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.
Apregen-150 Injection 1's contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.
Apregen-150 Injection 1's will be administered by a healthcare professional; do not self-administer. In some cases, Apregen-150 Injection 1's may cause common side effects such as headache, hiccups, tiredness, loss of appetite, indigestion, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately.
If you are allergic to Fosaprepitant or other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Apregen-150 Injection 1's. Drive only if you are alert after receiving Apregen-150 Injection 1's. If you are taking other prescription or non-prescription medicines, inform your doctor before receiving Apregen-150 Injection 1's.
Apregen-150 Injection 1's contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.
If you are allergic to Fosaprepitant or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Apregen-150 Injection 1's. Drive only if you are alert after receiving Apregen-150 Injection 1's. If you are taking any other prescription or non-prescription medicines, inform your doctor before receiving Apregen-150 Injection 1's. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Apregen-150 Injection 1's to check your blood clotting.
Drug-Drug Interactions: Avoid using Apregen-150 Injection 1's with antipsychotics (pimozide), anti-allergic drugs (astemizole, terfenadine), and gastroprokinetic agents (cisapride). Apregen-150 Injection 1's may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), a medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressants (nefazodone), a medicine used to treat high blood pressure (diltiazem), corticosteroids (dexamethasone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.
Drug-Food Interactions: Apregen-150 Injection 1's may interact with St. John’s Wort (herbal preparation used to treat depression).
Drug-Disease Interactions: If you have any liver problems, inform your doctor before receiving Apregen-150 Injection 1's.
Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.
Alcohol
Consult your doctor
The interaction of alcohol with Apregen-150 Injection 1's is unknown. If you have any concerns regarding this, please discuss them with your doctor.
Pregnancy
Consult your doctor
If you are pregnant or planning pregnancy, inform your doctor before receiving Apregen-150 Injection 1's. Your doctor may prescribe this medicine only if clearly needed.
Breast Feeding
Consult your doctor
It is unknown whether Fosaprepitant is excreted in breast milk. Hence, if you are a nursing mother, discuss with your doctor about the best way to feed your baby if you receive Apregen-150 Injection 1's.
Driving
Caution
Apregen-150 Injection 1's may cause dizziness or sleepiness in some people. Therefore, if you feel dizzy or sleepy after receiving Apregen-150 Injection 1's, avoid driving or operating machinery.
Liver
Caution
If you have liver disease, inform your doctor before receiving Apregen-150 Injection 1's.
Kidney
Consult your doctor
If you have any kidney problems, inform your doctor before receiving Apregen-150 Injection 1's.
Children
Caution
If you have any concerns regarding the use of Apregen-150 Injection 1's in children, please consult a doctor.
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