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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 30, 2024 | 3:22 PM IST
Amirix-Plus Tablet is used to treat moderate to severe depression associated with moderate to severe anxiety. It contains Amitriptyline and Chlordiazepoxide, which works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Also, it helps suppress the excessive and abnormal activity of the nerve cells in the brain. In some cases, you may experience common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Albiorix Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Amirix-Plus Tablet

Amirix-Plus Tablet is used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.

Amirix-Plus Tablet is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. 

You are advised to take Amirix-Plus Tablet only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take Amirix-Plus Tablet if you are pregnant, as it may cause birth defects. Consult your doctor before taking Amirix-Plus Tablet if you are breastfeeding. Avoid driving or operating machinery as Amirix-Plus Tablet causes sleepiness and dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Amirix-Plus Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Amirix-Plus Tablet

Treatment of Depression associated with anxiety

Medicinal Benefits

Amirix-Plus Tablet is a combination of two drugs: Amitriptyline and Chlordiazepoxide. Amirix-Plus Tablet is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. Amirix-Plus Tablet has a calming effect on various functions of the brain. Thereby, Amirix-Plus Tablet helps in treating anxiety and depression.

Side Effects of Amirix-Plus Tablet

  • Drowsiness
  • Dry mouth
  • Nasal congestion
  • Constipation
  • Blurred vision
  • Dizziness
  • Bloating

Directions for Use

Take Amirix-Plus Tablet with or without food. Swallow Amirix-Plus Tablet as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Amirix-Plus Tablet if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with Amirix-Plus Tablet as it may result in increased sedation, depression, coma and death. Amirix-Plus Tablet should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking Amirix-Plus Tablet if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking Amirix-Plus Tablet if you have a history of drug abuse, addiction or alcohol abuse as Amirix-Plus Tablet may cause dependence. Do not take Amirix-Plus Tablet if you are pregnant, as it may cause birth defects. Consult your doctor before taking Amirix-Plus Tablet if you are breastfeeding. Avoid driving or operating machinery as Amirix-Plus Tablet causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Amirix-Plus Tablet as it could lead to increased drowsiness and dizziness. Amirix-Plus Tablet should not be given to children as safety and effectiveness have not been established.

Therapeutic Class

PSYCHOTHERAPEUTICS

Drug-Drug Interactions

verifiedApollotooltip
AmitriptylinePhenelzine
Critical
AmitriptylineSaquinavir
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products and certain fruits and vegetables help in the proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

Yes

What if I have taken an overdose of Amirix-Plus Tablet

Do not take more than the prescribed dose of Amirix-Plus Tablet as it may cause overdose. The symptoms of overdose include difficulty sleeping, disorientation, dizziness, blurred vision, confusion, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, headache, loss of consciousness, fast/slow/irregular heartbeat, hallucinations, mood or other mental changes, seeing/hearing/feeling things that are not there, nightmares, seizures (fits), sweating, trouble breathing, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, or unusual excitement, nervousness, restlessness, or irritability. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Amirix-Plus Tablet as it may cause increased sleepiness and dizziness.

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Pregnancy

Unsafe

Avoid taking Amirix-Plus Tablet if you are pregnant unless prescribed by a doctor as it may cause birth defects.

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Breast Feeding

Caution

Consult your doctor before taking Amirix-Plus Tablet ; your doctor will decide whether Amirix-Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Amirix-Plus Tablet may cause sleepiness, dizziness and might impair thinking and motor skills. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Amirix-Plus Tablet should not be given to children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

556, Nalpada, Sandoz Baug, Thane (West), Maharashtra 400607
Other Info - AMI0524

Author Details

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FAQs

Amirix-Plus Tablet is used to treat moderate to severe depression associated with moderate to severe anxiety.
Amirix-Plus Tablet contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.
Amirix-Plus Tablet may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue Amirix-Plus Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Amirix-Plus Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Amirix-Plus Tablet .
Dry mouth could be a side-effect of Amirix-Plus Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Constipation might occur as a side-effect of Amirix-Plus Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.
Amirix-Plus Tablet may cause side effects like dizziness and tiredness in some people. Consult the doctor if the condition persists or if you experience severe dizziness or tiredness.
Painkillers should be taken with Amirix-Plus Tablet only if advised by the doctor. However, opioid-based analgesics should not be taken with Amirix-Plus Tablet as it may cause drowsiness and breathing problems. Always check with the doctor before taking painkillers or other medicines along with Amirix-Plus Tablet .
Amirix-Plus Tablet may cause suicidal thoughts/behaviour; therefore, monitor the person taking Amirix-Plus Tablet for any changes in mood/behaviour and report to the doctor if you notice any unusual behaviour.
Eat a healthy diet and exercise regularly to manage weight gain associated with the use of Amirix-Plus Tablet . Talk to the doctor if the increase in weight bothers you.
Store Amirix-Plus Tablet at room temperature, protected from light and moisture. Keep it out of sight and reach of children.
Yes, Amirix-Plus Tablet may cause sleepiness. Do not drive or operate machinery unless you know how the medicine affects you.
Amirix-Plus Tablet may cause sexual problems like decreased sexual desire, inability to reach an orgasm and erectile dysfunction in men. Discuss with the doctor if you experience sexual problems during treatment with Amirix-Plus Tablet .
No, do not drink alcohol while taking Amirix-Plus Tablet . Consuming alcohol along with Amirix-Plus Tablet could lead to increased drowsiness & dizziness and very serious side effects.
Amirix-Plus Tablet may change the colour of urine to green or blue. It is generally harmless and resolves once the medicine is stopped. However, consult the doctor if you have any concerns regarding this.
Amirix-Plus Tablet may start working within a week. However, it might take around 4 weeks to notice the full benefits of Amirix-Plus Tablet . Continue taking Amirix-Plus Tablet for the prescribed duration to treat your condition effectively.
The active ingredients of Amirix-Plus Tablet are Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). It is used to treat moderate to severe depression associated with moderate to severe anxiety.
Amirix-Plus Tablet can be taken with or without food as advised by the doctor. Swallow Amirix-Plus Tablet as a whole with a glass of water; do not chew or crush it.
Yes, Amirix-Plus Tablet is safe if taken in the dose and duration prescribed by the doctor. It should not be taken for longer durations as it may cause physical dependence.
Though Amirix-Plus Tablet may help you sleep better by improving your mood, it should not be used for sleep-related issues. Talk to the doctor if you have sleep-related problems.
Amirix-Plus Tablet may not be beneficial for heart health as it may cause QT prolongation (a condition that affects heart rhythm) in some people. Before starting treatment with Amirix-Plus Tablet discuss you’re your doctor if you have heart rhythm problems.
Side effects of Amirix-Plus Tablet include dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

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