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  1. Home
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  3. LIMBIVAL FORTE 25MG TABLET

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
LIMBIVAL FORTE 25MG TABLET is used to treat moderate to severe depression associated with moderate to severe anxiety. It contains Amitriptyline and Chlordiazepoxide, which works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Also, it helps suppress the excessive and abnormal activity of the nerve cells in the brain. In some cases, you may experience common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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LIMBIVAL FORTE 25MG TABLET, Pack of 10 TabletS
LIMBIVAL FORTE 25MG TABLET, Pack of 10 TabletS
LIMBIVAL FORTE 25MG TABLET, Pack of 10 TabletS
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Composition :

AMITRIPTYLINE-25MG + CHLORDIAZEPOXIDE-10MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About LIMBIVAL FORTE 25MG TABLET

LIMBIVAL FORTE 25MG TABLET is used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.

LIMBIVAL FORTE 25MG TABLET is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. 

You are advised to take LIMBIVAL FORTE 25MG TABLET only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take LIMBIVAL FORTE 25MG TABLET if you are pregnant, as it may cause birth defects. Consult your doctor before taking LIMBIVAL FORTE 25MG TABLET if you are breastfeeding. Avoid driving or operating machinery as LIMBIVAL FORTE 25MG TABLET causes sleepiness and dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with LIMBIVAL FORTE 25MG TABLET as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of LIMBIVAL FORTE 25MG TABLET

Treatment of Depression associated with anxiety

Directions for Use

Take LIMBIVAL FORTE 25MG TABLET with or without food. Swallow LIMBIVAL FORTE 25MG TABLET as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

LIMBIVAL FORTE 25MG TABLET is a combination of two drugs: Amitriptyline and Chlordiazepoxide. LIMBIVAL FORTE 25MG TABLET is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. LIMBIVAL FORTE 25MG TABLET has a calming effect on various functions of the brain. Thereby, LIMBIVAL FORTE 25MG TABLET helps in treating anxiety and depression.

How LIMBIVAL FORTE 25MG TABLET Works

LIMBIVAL FORTE 25MG TABLET is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of LIMBIVAL FORTE 25MG TABLET

  • Drowsiness
  • Dry mouth
  • Nasal congestion
  • Constipation
  • Blurred vision
  • Dizziness
  • Bloating

What if I have taken an overdose of LIMBIVAL FORTE 25MG TABLET

Do not take more than the prescribed dose of LIMBIVAL FORTE 25MG TABLET as it may cause overdose. The symptoms of overdose include difficulty sleeping, disorientation, dizziness, blurred vision, confusion, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, headache, loss of consciousness, fast/slow/irregular heartbeat, hallucinations, mood or other mental changes, seeing/hearing/feeling things that are not there, nightmares, seizures (fits), sweating, trouble breathing, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, or unusual excitement, nervousness, restlessness, or irritability. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take LIMBIVAL FORTE 25MG TABLET if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with LIMBIVAL FORTE 25MG TABLET as it may result in increased sedation, depression, coma and death. LIMBIVAL FORTE 25MG TABLET should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking LIMBIVAL FORTE 25MG TABLET if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking LIMBIVAL FORTE 25MG TABLET if you have a history of drug abuse, addiction or alcohol abuse as LIMBIVAL FORTE 25MG TABLET may cause dependence. Do not take LIMBIVAL FORTE 25MG TABLET if you are pregnant, as it may cause birth defects. Consult your doctor before taking LIMBIVAL FORTE 25MG TABLET if you are breastfeeding. Avoid driving or operating machinery as LIMBIVAL FORTE 25MG TABLET causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with LIMBIVAL FORTE 25MG TABLET as it could lead to increased drowsiness and dizziness. LIMBIVAL FORTE 25MG TABLET should not be given to children as safety and effectiveness have not been established.

Drug-Drug Interactions

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AmitriptylineBepridil
Critical
AmitriptylinePotassium chloride
Critical

Drug-Drug Interactions

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AmitriptylineBepridil
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Combining LIMBIVAL FORTE 25MG TABLET and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining LIMBIVAL FORTE 25MG TABLET with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylinePotassium chloride
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
The combination of LIMBIVAL FORTE 25MG TABLET and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of LIMBIVAL FORTE 25MG TABLET and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
AmitriptylineRasagiline
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Using LIMBIVAL FORTE 25MG TABLET together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and LIMBIVAL FORTE 25MG TABLET together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken LIMBIVAL FORTE 25MG TABLET. Do not discontinue any medications without consulting a doctor.
AmitriptylineDronedarone
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Combining LIMBIVAL FORTE 25MG TABLET and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining LIMBIVAL FORTE 25MG TABLET with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineZiprasidone
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Taking LIMBIVAL FORTE 25MG TABLET and Ziprasidone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although there is a interaction between LIMBIVAL FORTE 25MG TABLET with Ziprasidone, but it can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats . Do not discontinue any medication without consulting a doctor.
AmitriptylineFurazolidone
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Combining Furazolidone with LIMBIVAL FORTE 25MG TABLET can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and LIMBIVAL FORTE 25MG TABLET together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken LIMBIVAL FORTE 25MG TABLET. Do not discontinue any medications without consulting a doctor.
AmitriptylinePimozide
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Combining LIMBIVAL FORTE 25MG TABLET and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining LIMBIVAL FORTE 25MG TABLET with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineMethylene blue
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Combining Methylene blue with LIMBIVAL FORTE 25MG TABLET can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Methylene blue and LIMBIVAL FORTE 25MG TABLET together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken LIMBIVAL FORTE 25MG TABLET. Do not discontinue any medications without consulting a doctor.
AmitriptylineSelegiline
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Co-administration of LIMBIVAL FORTE 25MG TABLET together with Selegiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Selegiline and LIMBIVAL FORTE 25MG TABLET together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken LIMBIVAL FORTE 25MG TABLET. Do not discontinue any medications without consulting a doctor.
AmitriptylineSparfloxacin
Critical
How does the drug interact with LIMBIVAL FORTE 25MG TABLET:
Combining LIMBIVAL FORTE 25MG TABLET and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining LIMBIVAL FORTE 25MG TABLET with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products and certain fruits and vegetables help in the proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

Yes

Therapeutic Class

PSYCHOTHERAPEUTICS

LIMBIVAL FORTE 25MG TABLET Substitute

Substitutes safety advice

  • Libotryp DS Tablet 30's

    ₹7.52per tablet

  • Amixide Tablet 10's

    ₹6.84per tablet

  • LIMBITROL TABLET

    ₹7.02per tablet

  • EMOTRIP 25MG TABLET

    ₹3.65per tablet

  • CHLOTRIP DS TABLET

    ₹4.32per tablet

Product Substitutes

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Libotryp DS Tablet 30's

₹225.5

MRP ₹250.5

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Amixide Tablet 10's

₹68.4

MRP ₹76

Info icon

LIMBITROL TABLET

₹70.2

MRP ₹78

Info icon

EMOTRIP 25MG TABLET

₹36.5

MRP ₹40.5

Info icon

CHLOTRIP DS TABLET

₹43.2

MRP ₹48

Info icon

CHLORAMIT TABLET

₹66.6

MRP ₹74

Info icon

AMICHLOR DS TABLET

₹24.97

MRP ₹27.75

Info icon

Amizep Tablet 10's

₹37.35

MRP ₹41.5

Info icon

AMITRYN C PLUS TABLET

₹85.5

MRP ₹95

Info icon

Amitone Forte Tablet 10's

₹61.2

MRP ₹68

Info icon

Amitop Plus Tablet 10's

₹43.2

MRP ₹48

Info icon

Amicon Forte Tablet 10's

₹63

MRP ₹70

Info icon

Relidep Plus 25 Mg Fc Tablet 10's

₹56.7

MRP ₹63

Info icon

Merital 10mg Tablet 10's

₹64.8

MRP ₹72

Info icon

Libotryp XL 25 mg Tablet 10's

₹108.9

MRP ₹121

Info icon

TRIXIDE TABLET

₹35.6

MRP ₹39.5

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Alcohol

Unsafe

Avoid consumption of alcohol while taking LIMBIVAL FORTE 25MG TABLET as it may cause increased sleepiness and dizziness.

bannner image

Pregnancy

Unsafe

Avoid taking LIMBIVAL FORTE 25MG TABLET if you are pregnant unless prescribed by a doctor as it may cause birth defects.

bannner image

Breast Feeding

Caution

Consult your doctor before taking LIMBIVAL FORTE 25MG TABLET; your doctor will decide whether LIMBIVAL FORTE 25MG TABLET can be taken by breastfeeding mothers or not.

bannner image

Driving

Unsafe

LIMBIVAL FORTE 25MG TABLET may cause sleepiness, dizziness and might impair thinking and motor skills. Do not drive or operate machinery if you experience these symptoms.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

LIMBIVAL FORTE 25MG TABLET should not be given to children as safety and effectiveness have not been established.

FAQs

LIMBIVAL FORTE 25MG TABLET is used to treat moderate to severe depression associated with moderate to severe anxiety.
LIMBIVAL FORTE 25MG TABLET contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.
LIMBIVAL FORTE 25MG TABLET may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue LIMBIVAL FORTE 25MG TABLET without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking LIMBIVAL FORTE 25MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking LIMBIVAL FORTE 25MG TABLET.
Dry mouth could be a side-effect of LIMBIVAL FORTE 25MG TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Constipation might occur as a side-effect of LIMBIVAL FORTE 25MG TABLET. Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.
LIMBIVAL FORTE 25MG TABLET may cause side effects like dizziness and tiredness in some people. Consult the doctor if the condition persists or if you experience severe dizziness or tiredness.
Painkillers should be taken with LIMBIVAL FORTE 25MG TABLET only if advised by the doctor. However, opioid-based analgesics should not be taken with LIMBIVAL FORTE 25MG TABLET as it may cause drowsiness and breathing problems. Always check with the doctor before taking painkillers or other medicines along with LIMBIVAL FORTE 25MG TABLET.
LIMBIVAL FORTE 25MG TABLET may cause suicidal thoughts/behaviour; therefore, monitor the person taking LIMBIVAL FORTE 25MG TABLET for any changes in mood/behaviour and report to the doctor if you notice any unusual behaviour.
Eat a healthy diet and exercise regularly to manage weight gain associated with the use of LIMBIVAL FORTE 25MG TABLET. Talk to the doctor if the increase in weight bothers you.
Store LIMBIVAL FORTE 25MG TABLET at room temperature, protected from light and moisture. Keep it out of sight and reach of children.
Yes, LIMBIVAL FORTE 25MG TABLET may cause sleepiness. Do not drive or operate machinery unless you know how the medicine affects you.
LIMBIVAL FORTE 25MG TABLET may cause sexual problems like decreased sexual desire, inability to reach an orgasm and erectile dysfunction in men. Discuss with the doctor if you experience sexual problems during treatment with LIMBIVAL FORTE 25MG TABLET.
No, do not drink alcohol while taking LIMBIVAL FORTE 25MG TABLET. Consuming alcohol along with LIMBIVAL FORTE 25MG TABLET could lead to increased drowsiness & dizziness and very serious side effects.
LIMBIVAL FORTE 25MG TABLET may change the colour of urine to green or blue. It is generally harmless and resolves once the medicine is stopped. However, consult the doctor if you have any concerns regarding this.
LIMBIVAL FORTE 25MG TABLET may start working within a week. However, it might take around 4 weeks to notice the full benefits of LIMBIVAL FORTE 25MG TABLET. Continue taking LIMBIVAL FORTE 25MG TABLET for the prescribed duration to treat your condition effectively.
The active ingredients of LIMBIVAL FORTE 25MG TABLET are Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). It is used to treat moderate to severe depression associated with moderate to severe anxiety.
LIMBIVAL FORTE 25MG TABLET can be taken with or without food as advised by the doctor. Swallow LIMBIVAL FORTE 25MG TABLET as a whole with a glass of water; do not chew or crush it.
Yes, LIMBIVAL FORTE 25MG TABLET is safe if taken in the dose and duration prescribed by the doctor. It should not be taken for longer durations as it may cause physical dependence.
Though LIMBIVAL FORTE 25MG TABLET may help you sleep better by improving your mood, it should not be used for sleep-related issues. Talk to the doctor if you have sleep-related problems.
LIMBIVAL FORTE 25MG TABLET may not be beneficial for heart health as it may cause QT prolongation (a condition that affects heart rhythm) in some people. Before starting treatment with LIMBIVAL FORTE 25MG TABLET discuss you’re your doctor if you have heart rhythm problems.
Side effects of LIMBIVAL FORTE 25MG TABLET include dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - LIM0007

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Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:49 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016949s040lbl.pdf
  2. https://www.drugs.com/mtm/amitriptyline-and-chlordiazepoxide.html
  3. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=66a756f2-ac77-451c-a19a-08896d73b15c
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