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Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST
Ambristar 5 Tablet is used to treat pulmonary arterial hypertension (high blood pressure in the lungs). It contains Ambrisentan which works by widening the blood vessels and improving blood flow. In some cases, this medicine may cause side effects such as headache, dizziness, breathlessness, runny nose, feeling sick, diarrhoea, and fatigue. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition :

AMBRISENTAN-5MG

Manufacturer/Marketer :

Steris Healthcare

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Ambristar 5 Tablet

Ambristar 5 Tablet is used to treat high blood pressure in the arteries of the lungs (pulmonary arterial hypertension). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the walls of blood vessels. This condition makes the heart work harder in pumping the blood to the whole body. Pulmonary hypertension affects arteries in the lungs and the right side of the heart.

Ambristar 5 Tablet contains ‘Ambrisentan,’ which belongs to the class of ‘endothelin receptor blockers’. Ambrisentan works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. Ambristar 5 Tablet widens the constricted pulmonary arteries (blood vessels that carry blood from the heart to the lungs) and increases blood supply to the lungs, thus lowering the blood pressure.

In some cases, Ambristar 5 Tablet can cause side effects like headache, dizziness, palpitations, breathlessness, runny nose, feeling sick, diarrhoea, and fatigue. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Please inform your doctor if you are using any prescription or non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to Ambristar 5 Tablet or any other medicines, before starting Ambristar 5 Tablet . Inform your doctor if you have low blood pressure, lung, heart, kidney or liver problems, and anaemia (lack of blood cells). It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Do not stop taking Ambristar 5 Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Do not consume alcohol with Ambristar 5 Tablet as it may increase the risk of low blood pressure.

Uses of Ambristar 5 Tablet

Treatment of Pulmonary arterial hypertension.

Medicinal Benefits

Ambristar 5 Tablet is an anti-hypertensive medicine that treats high blood pressure in the arteries of the lungs (pulmonary arterial hypertension (PAH)). It contains ‘Ambrisentan,’ an endothelin receptor blocker. Ambristar 5 Tablet works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. In people with PAH, the pulmonary arteries get narrower making the heart work harder to pump blood through them. Ambristar 5 Tablet widens these constricted arteries and makes it easier for the heart to pump blood, thus lowering the blood pressure.

Side Effects of Ambristar 5 Tablet

  • Headache
  • Dizziness
  • Swelling in your hands, legs, ankles, or feet
  • Palpitations
  • Breathlessness
  • Chest pain or discomfort
  • Stuffy nose, sinus pain
  • Flushing (redness of the skin)
  • Feeling sick
  • Diarrhoea
  • Feeling tired
  • Rash

Directions for Use

Swallow Ambristar 5 Tablet as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Brief your medical history if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure) before starting Ambristar 5 Tablet . Ambristar 5 Tablet is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using Ambristar 5 Tablet if you are a breastfeeding mother. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Do not drive or operate machinery since Ambristar 5 Tablet may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Ambristar 5 Tablet as it may increase the risk of low blood pressure. Ambristar 5 Tablet is not recommended in patients younger than 18 years of age.

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Drug Interactions

verifiedApollotooltip
AmbrisentanLeflunomide
Severe
AmbrisentanLomitapide
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.

  • Eat natural and healthy foods by cutting down on high on sodium processed foods.

  • Lose those extra pounds, since being obese can be a risk factor for hypertension.

  • Exercise regularly to maintain good heart health.

  • Avoid smoking and alcohol intake.

  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.

  • Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

Habit Forming

No

How Ambristar 5 Tablet Works

Ambristar 5 Tablet contains Ambrisentan, which belongs to the class of endothelin receptor blockers. Ambrisentan works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. Ambristar 5 Tablet widens the constricted pulmonary arteries (blood vessels that carry blood from the heart to the lungs) and increases blood supply to the lungs, thus lowering the blood pressure.

What if I have taken an overdose of Ambristar 5 Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sweating, confusion, blurred vision, dizziness, light-headedness when getting up suddenly from a sitting/lying position, or faintness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Caution

It is advised to limit alcohol intake, since alcohol consumption with Ambristar 5 Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

Ambristar 5 Tablet is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. You are advised to get a pregnancy test done before starting Ambristar 5 Tablet . You should get a negative pregnancy test for sure before using Ambristar 5 Tablet . Also, please use reliable forms of birth control if you are undergoing treatment with Ambristar 5 Tablet to avoid pregnancy.

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Breast Feeding

Caution

It is not known if Ambristar 5 Tablet is excreted into the breast milk. Please consult your doctor for more information before taking Ambristar 5 Tablet if you are a nursing mother.

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Driving

Caution

Ambristar 5 Tablet may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Ambristar 5 Tablet . Ambristar 5 Tablet may cause an increase in liver enzymes. If you are using Ambristar 5 Tablet and experience any nausea, vomiting, loss of appetite, dark-coloured urine and yellowing of the skin, please see your doctor immediately.

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Kidney

Caution

Ambristar 5 Tablet should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Ambristar 5 Tablet if you have any kidney problems.

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Children

Unsafe

Safety and effectiveness of Ambristar 5 Tablet have not been established in patients below 18 years of age.

Country of origin

India

Manufacturer/Marketer address

Tanaji Chowk, Mumbai
Other Info - AMB0440

Author Details

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FAQs

Ambristar 5 Tablet is used to treat Pulmonary arterial hypertension.
Ambristar 5 Tablet consists of Ambrisentan. It is an anti-hypertensive medicine that lowers the blood pressure by widening the pulmonary arteries and making the heart pump blood efficiently.
Yes, Ambristar 5 Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve from dizziness. If the side effect persists longer, please seek medical help.
Do not stop using Ambristar 5 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Ambristar 5 Tablet should be used with caution in cases of any allergic reactions, heart failure, liver, kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure).
Store Ambristar 5 Tablet away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of the sight and reach of children.
Ambristar 5 Tablet may rarely cause liver problems. Your doctor will monitor your liver function while you're taking Ambristar 5 Tablet . If you experience symptoms like yellowing skin, dark urine, or abdominal pain, seek medical attention. Discuss any concerns with your doctor.
Take Ambristar 5 Tablet exactly as your doctor tells you to. Typically, it's one tablet once a day. Swallow the tablet whole with water, and take it at the same time each day. Don't crush, chew, or break it.
Don't stop taking Ambristar 5 Tablet without talking to your doctor first. Stopping suddenly can worsen your condition and increase the risk of heart problems. Your doctor will advise you on how to safely stop taking Ambristar 5 Tablet if needed. Follow their instructions carefully.
Ambristar 5 Tablet is used to treat high blood pressure in the lungs, but have risks and limitations. They can cause serious side effects and may not be suitable for everyone, including pregnant women and those with certain medical conditions. Always follow your doctor's instructions and ask questions if needed.
Ambristar 5 Tablet can be effective in treating certain conditions, but in some cases, it can cause serious side effects. Watch out for severe swelling, difficulty breathing or swallowing, and sudden weight gain. Additionally, be aware of extreme tiredness, yellowing of the skin or eyes, dark urine, and severe itching. If you experience any of these symptoms, call your doctor right away or seek emergency medical help. Don't delay; these side effects can be serious and require prompt attention. Discussing the potential risks and benefits with your doctor before starting treatment is essential.
You have been prescribed Ambristar 5 Tablet to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the lungs.
Avoid exceeding the recommended dose, as it could lead to an overdose. Symptoms of overdose may include sweating, confusion, blurred vision, dizziness, light-headedness when getting up suddenly from a sitting/lying position, or faintness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
Common side effects of Ambristar 5 Tablet may include headache, dizziness, palpitations, breathlessness, runny nose, feeling sick, diarrhoea, and fatigue. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
No, you should not take Ambristar 5 Tablet on your own without consulting a doctor. This medication is prescribed for specific medical conditions and requires a doctor's supervision to ensure safe and effective use.
Safety and effectiveness of Ambristar 5 Tablet have not been established in patients below 18 years of age.

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