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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Alporate-300 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It contains Sodium valproate, which decreases the excessive and abnormal nerve activity in the brain. Thereby, helps in controlling seizures. It helps block the nerve transmission across the brain and provides a calming effect. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Alteus Biogenics Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Alporate-300 Tablet

Alporate-300 Tablet is used to treat epilepsy/seizures/fits. Additionally, Alporate-300 Tablet is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 
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Alporate-300 Tablet contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Alporate-300 Tablet increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
You can take Alporate-300 Tablet with or without food. You are advised to take Alporate-300 Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Please do not stop taking Alporate-300 Tablet without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first period whilst on treatment with Alporate-300 Tablet . Do not take Alporate-300 Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Alporate-300 Tablet . Consult your doctor before taking Alporate-300 Tablet if you are breastfeeding. Do not drive or operate machinery as Alporate-300 Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Alporate-300 Tablet as it could lead to increased dizziness and sleepiness.

Uses of Alporate-300 Tablet

Treatment of Epilepsy, Bipolar Disorder, Migraine.

Medicinal Benefits

Alporate-300 Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Alporate-300 Tablet is also used to treat bipolar disorder and prevent migraine headaches. Alporate-300 Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Alporate-300 Tablet is used to treat both localized (seizures which affect only a part of the brain) and generalized seizures (seizures which affect the entire brain).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not chew or break the tablet/capsule. Oral solution: Take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe; shake the pack well before each use.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alporate-300 Tablet

  • Stomach pain
  • Nausea
  • Vomiting
  • Dry mouth
  • Tremors
  • Tiredness
  • Sleepiness
  • Headache
  • Weight gain
  • Hair loss

Drug Warnings

Do not take Alporate-300 Tablet if you are allergic to any of its contents; if you have liver problems, porphyria, urine-related problems (like urea cycle disorder), diabetes, immune system disorder or kidney problems. Consult your doctor immediately if you experience suicidal tendencies while taking Alporate-300 Tablet . Contact your doctor if your child gets her first period during the treatment with Alporate-300 Tablet . Do not take Alporate-300 Tablet if you are pregnant unless prescribed by the doctor as it is pregnancy category C medicine and can cause serious congenital disabilities. Consult your doctor before taking Alporate-300 Tablet if you are breastfeeding. Alporate-300 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Alporate-300 Tablet as it could lead to increased dizziness and sleepiness. 

Drug Interactions

Drug-Drug Interactions: Alporate-300 Tablet may have interaction with pain killers (aspirin), anti-epileptics (phenobarbital, primidone, phenytoin, carbamazepine, topiramate, acetazolamide, lamotrigine, felbamate), blood thinner (warfarin), anti-HIV (zidovudine, lopinavir, ritonavir), anti-depressant (moclobemide, selegiline, linezolid, amitriptyline, sertraline), anti-psychotic (quetiapine, olanzapine, risperidone), calcium channel blocker (nimodipine), anaesthetic (propofol), hormone (oestrogen, levonorgestrel), anti-malarial (mefloquine, chloroquine), antacid (cimetidine), antibiotics (imipenem, meropenem, rifampicin, erythromycin), bile-acid sequestrant (cholestyramine), benzodiazepine (clonazepam, diazepam).

Drug-Food Interactions: Avoid alcohol consumption while taking Alporate-300 Tablet as it might cause increased dizziness and sleepiness. 

Drug-Disease Interactions: Inform your doctor if you have depression, liver disease, urea cycle disorders, suicidal tendency, HIV disease, or thrombocytopenia (low levels of platelets).

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • ACETAZOLAMIDE
  • LAMOTRIGINE
  • FELBAMATE
  • WARFARIN
  • ZIDOVUDINE
  • LOPINAVIR
  • RITONAVIR
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • NIMODIPINE
  • PROPOFOL
  • ESTROGEN
  • LEVONORGESTREL
  • MEFLOQUINE
  • CHLOROQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLONAZEPAM
  • DIAZEPAM
  • CHOLESTYRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.

  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well; get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan that helps those around you know what to do.

  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Special Advise

  • Contact your doctor if your child gets her first-period whilst on treatment with Alporate-300 Tablet .

  • Alporate-300 Tablet might affect blood and urine tests. Inform the person doing the tests that you are taking Alporate-300 Tablet .

  • If you are of child-bearing age, use effective contraception without interruptions during your entire treatment with Alporate-300 Tablet .

  • Consult your doctor immediately if you become pregnant while taking Alporate-300 Tablet .

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Alporate-300 Tablet as it may cause increased dizziness and sleepiness.

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Pregnancy

Unsafe

Alporate-300 Tablet belongs to pregnancy category D. Avoid taking Alporate-300 Tablet if you are pregnant as it could lead to serious birth defects.

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Breast Feeding

Caution

Alporate-300 Tablet may pass into breastmilk. Consult your doctor before taking Alporate-300 Tablet if you are breastfeeding.

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Driving

Unsafe

Alporate-300 Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Alporate-300 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Alporate-300 Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Country of origin

INDIA

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, WB, India.
Other Info - ALP0250

Author Details

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FAQs

Alporate-300 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).
Alporate-300 Tablet decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.
Alporate-300 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.
Alporate-300 Tablet limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.
Do not discontinue Alporate-300 Tablet without consulting your doctor. To treat your condition effectually, continue taking Alporate-300 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Alporate-300 Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.
Birth-control pills like oestrogen-containing products may affect the way Alporate-300 Tablet works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.
Alporate-300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.
Alporate-300 Tablet might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Alporate-300 Tablet . In rare cases, Alporate-300 Tablet can be a contributing factor in male infertility.
Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.
Alporate-300 Tablet may change the results of liver enzymes, and urine and blood tests. Inform the person doing the tests that you are taking Alporate-300 Tablet .
Store Alporate-300 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Alporate-300 Tablet may cause side effects like stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No, avoid consumption of alcohol while taking Alporate-300 Tablet as it may cause increased dizziness and sleepiness.
Yes, Alporate-300 Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
No, taking higher than the recommended dose of Alporate-300 Tablet will not be more effective and may cause unpleasant side effects. Do not take more than the prescribed dose of Alporate-300 Tablet as it may cause an overdose.

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