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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Aggrenox 200mg/25mg Capsule is used to prevent stroke. It contains Aspirin and Dipyridamole which inhibit the platelets from sticking together, thereby preventing the formation of blood clots. In some cases, this medicine may cause side effects such as headache, dizziness, heartburn, nausea, indigestion, diarrhoea, and stomach pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Aggrenox 200mg/25mg Capsule

Aggrenox 200mg/25mg Capsule belongs to the class of ‘anticoagulants’ used to prevent stroke who have had blood clots or had a mini-stroke. Stroke, also called cerebrovascular (CV) or brain stroke, occurs due to insufficient blood supply to the brain. It causes a decrease in oxygen and nutrient supply to the brain, impairing the function of the brain. This condition requires immediate medical attention to prevent permanent brain damage.

Aggrenox 200mg/25mg Capsule contains Aspirin and Dipyridamole. Aspirin is a blood thinner. It has antithrombotic action that interferes with platelet functioning and does not let them stick together. Dipyridamole is an anticoagulant agent. It prevents the platelets from sticking together, thereby preventing the formation of blood clots. Together, Aggrenox 200mg/25mg Capsule can effectively reduce the risk of stroke. 

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Aggrenox 200mg/25mg Capsule are headache, dizziness, heartburn, nausea, indigestion, diarrhea, and stomach pain. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Aggrenox 200mg/25mg Capsule if you are allergic to aspirin, dipyridamole, or non-steroidal anti-inflammatory drugs (NSAIDs). It should not be used in patients with asthma, rhinitis (stuffy nose), and nasal polyps (painless, benign growths on the nose's linings). It is also not recommended for children younger than 16 years of age with a fever, flu, or viral infections. Inform your doctor if you are pregnant or breastfeeding. Aggrenox 200mg/25mg Capsule may require dose adjustments when used in elderly people. Do not consume alcohol as it increases the risk of side-effects. Aggrenox 200mg/25mg Capsule may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Aggrenox 200mg/25mg Capsule

Treatment of Stroke

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Aggrenox 200mg/25mg Capsule is used to reduce stroke risk in patients who had a history of blood clots or a mini-stroke (also called transient ischemic attack). Aggrenox 200mg/25mg Capsule is a combination of two medicines: Aspirin and Dipyridamole. This medicine helps to maintain normal blood flow to the brain. It can prevent the formation of clots, thereby reducing the risk of stroke. 

How Aggrenox 200mg/25mg Capsule Works

Aggrenox 200mg/25mg Capsule contains Aspirin and Dipyridamole. Aspirin is a blood thinner. It has antithrombotic action that interferes with platelet functioning and does not let them stick together. Dipyridamole is an anticoagulant agent. It prevents the platelets from sticking together, thereby preventing the formation of blood clots. Together, Aggrenox 200mg/25mg Capsule can effectively reduce the risk of stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aggrenox 200mg/25mg Capsule

  • Headache
  • Dizziness
  • Heartburn
  • Nausea
  • Indigestion
  • Diarrhea
  • Stomach pain
  • Fatigue 
  • Joint pains

What if I have taken an overdose of Aggrenox 200mg/25mg Capsule

Take Aggrenox 200mg/25mg Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include warmth or tingly feeling, restlessness, sweating, dizziness, fast heartbeats, weakness, or ringing in your ears. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking Aggrenox 200mg/25mg Capsule, inform your doctor if you have stomach ulcers, bleeding problems, heart problems, hypotension (low blood pressure), and myasthenia gravis (a muscle disorder). The use of Aggrenox 200mg/25mg Capsule in children below 16 years with viral infections may lead to Reye’s syndrome (a life-threatening condition that causes liver and brain damage). Aggrenox 200mg/25mg Capsule may cause headaches during the initial days of therapy. Let your doctor know if the headache is severe. Aggrenox 200mg/25mg Capsule can increase the bleeding risk even due to a minor injury, so seek medical attention if you suffer any injury and have uncontrolled bleeding. Inform your doctor if you experience blood in your sputum or vomit, blood in urine, or dark-colored stools, as it can be a sign of stomach bleeding.

Drug-Drug Interactions

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DipyridamoleDalteparin
Critical
DipyridamoleRiociguat
Critical

Drug-Drug Interactions

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DipyridamoleDalteparin
Critical
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Combining Aggrenox 200mg/25mg Capsule with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Aggrenox 200mg/25mg Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DipyridamoleRiociguat
Critical
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Taking Aggrenox 200mg/25mg Capsule with Riociguat may lower blood pressure.

How to manage the interaction:
Taking Aggrenox 200mg/25mg Capsule with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion Do not discontinue any medications without consulting a doctor.
AspirinKetorolac
Critical
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Co-administration of Ketorolac and Aggrenox 200mg/25mg Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Aggrenox 200mg/25mg Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
AspirinKetorolac tromethamine
Critical
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Combining Ketorolac tromethamine with Aggrenox 200mg/25mg Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Aggrenox 200mg/25mg Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
DipyridamoleDeferasirox
Severe
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Combining Aggrenox 200mg/25mg Capsule with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Aggrenox 200mg/25mg Capsule with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DipyridamoleCaffeine
Severe
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Concomitant use of caffeine with Aggrenox 200mg/25mg Capsule may decrease the effects of Aggrenox 200mg/25mg Capsule.

How to manage the interaction:
Although there is an interaction, caffeine can be taken with Aggrenox 200mg/25mg Capsule if prescribed by the doctor. Avoiding caffeine for 12 to 24 hours before Aggrenox 200mg/25mg Capsule administration is advised.
DipyridamoleDasatinib
Severe
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Coadministration of Dasatinib with Aggrenox 200mg/25mg Capsule can increase the risk of bleeding tendencies.

How to manage the interaction:
Co-administration of Dasatinib with Aggrenox 200mg/25mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like bruising, feeling dizzy or lightheaded, having dark stools, headaches, weakness, - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DipyridamolePrasugrel
Severe
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Co-administration of Aggrenox 200mg/25mg Capsule with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Taking Prasugrel with Aggrenox 200mg/25mg Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
DipyridamoleApixaban
Severe
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Coadministration of Aggrenox 200mg/25mg Capsule and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Aggrenox 200mg/25mg Capsule and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
DipyridamoleDabigatran etexilate
Severe
How does the drug interact with Aggrenox 200mg/25mg Capsule:
Taking Dabigatran etexilate with Aggrenox 200mg/25mg Capsule can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Aggrenox 200mg/25mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more green, leafy vegetables and other non-starchy vegetables (tomatoes, broccoli, and cauliflower, etc.) in your diet.
  • Eat strawberries, blueberries, blackberries, and nuts as they reduce inflammation in the brain.
  • Use olive oil for cooking purposes. It contains healthy fats that promote brain health. 
  • Eat whole grains such as oats, quinoa, and brown rice that are rich in nutrients.
  • Opt for fish oil or eat fish (preferably fatty fish like salmon, sardines, trout, and tuna) at least once a week. They are rich in omega-3 fatty acids that are essential for the normal functioning of the brain.
  • Avoid fried, processed, and packed foods.
  • Exercise regularly. It helps to maintain a normal weight and reduce cholesterol levels.
  • Quit alcohol intake and smoking.

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Aggrenox 200mg/25mg Capsule Substitute

Substitutes safety advice
  • Arreno Capsule 10's

    3.78per tablet
  • Aggrenox 200 mg/25 mg Capsule 60's

    38.91per tablet
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Alcohol

Unsafe

Do not consume alcohol as it increases the risk of bleeding.

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Pregnancy

Unsafe

Aggrenox 200mg/25mg Capsule is not recommended for use in pregnant women as it may cause harmful effects in the unborn baby. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Aggrenox 200mg/25mg Capsule is not recommended for use in breastfeeding mothers as it may cause harmful effects in the nursing baby. Consult your doctor for further advice.

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Driving

Caution

Aggrenox 200mg/25mg Capsule may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

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Liver

Caution

Aggrenox 200mg/25mg Capsule should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Aggrenox 200mg/25mg Capsule should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Aggrenox 200mg/25mg Capsule should be used in children only if clinically needed. It should not be used in children less than 16 years of age who have viral infections.

FAQs

Aggrenox 200mg/25mg Capsule is used to prevent stroke in people who have had blood clots or had a mini-stroke.
Aggrenox 200mg/25mg Capsule contains Aspirin and Dipyridamole. Aspirin is a blood thinner. It has antithrombotic action that interferes with platelet functioning and does not let them stick together. Dipyridamole is an anticoagulant agent. It prevents the platelets from sticking together, thereby preventing the formation of blood clots. Together, Aggrenox 200mg/25mg Capsule can effectively reduce the risk of stroke.Â
The common side-effects of Aggrenox 200mg/25mg Capsule are headache, dizziness, heartburn, nausea, indigestion, diarrhea, and stomach pain. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Aggrenox 200mg/25mg Capsule should not be used in patients with asthma. This medicine contains aspirin which may induce an asthma attack or worsen the condition.
Aggrenox 200mg/25mg Capsule increases the risk of bleeding. So, be cautious while using sharp objects, knives, nail clippers, or engaging in contact sports such as football, basketball, or wrestling to avoid injuries. In addition, let your doctor know that you are taking Aggrenox 200mg/25mg Capsule before undergoing a surgery or dental procedure to prevent excessive bleeding.
You can take Aggrenox 200mg/25mg Capsule safely as long as your doctor has prescribed it to you. It is usually prescribed for the long-term to reduce the risk of stroke.

Country of origin

India

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11Th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - AGG0006

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