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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Aggrenox 200 mg/25 mg Capsule is used to prevent stroke. It contains Aspirin and Dipyridamole which inhibit the platelets from sticking together, thereby preventing the formation of blood clots. In some cases, this medicine may cause side effects such as headache, dizziness, heartburn, nausea, indigestion, diarrhoea, and stomach pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Aggrenox 200 mg/25 mg Capsule

Aggrenox 200 mg/25 mg Capsule belongs to the class of ‘anticoagulants’ used to prevent stroke who have had blood clots or had a mini-stroke. Stroke, also called cerebrovascular (CV) or brain stroke, occurs due to insufficient blood supply to the brain. It causes a decrease in oxygen and nutrient supply to the brain, impairing the function of the brain. This condition requires immediate medical attention to prevent permanent brain damage.

Aggrenox 200 mg/25 mg Capsule contains Aspirin and Dipyridamole. Aspirin is a blood thinner. It has antithrombotic action that interferes with platelet functioning and does not let them stick together. Dipyridamole is an anticoagulant agent. It prevents the platelets from sticking together, thereby preventing the formation of blood clots. Together, Aggrenox 200 mg/25 mg Capsule can effectively reduce the risk of stroke. 

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Aggrenox 200 mg/25 mg Capsule are headache, dizziness, heartburn, nausea, indigestion, diarrhea, and stomach pain. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Aggrenox 200 mg/25 mg Capsule if you are allergic to aspirin, dipyridamole, or non-steroidal anti-inflammatory drugs (NSAIDs). It should not be used in patients with asthma, rhinitis (stuffy nose), and nasal polyps (painless, benign growths on the nose's linings). It is also not recommended for children younger than 16 years of age with a fever, flu, or viral infections. Inform your doctor if you are pregnant or breastfeeding. Aggrenox 200 mg/25 mg Capsule may require dose adjustments when used in elderly people. Do not consume alcohol as it increases the risk of side-effects. Aggrenox 200 mg/25 mg Capsule may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Aggrenox 200 mg/25 mg Capsule

Treatment of Stroke

Medicinal Benefits

Aggrenox 200 mg/25 mg Capsule is used to reduce stroke risk in patients who had a history of blood clots or a mini-stroke (also called transient ischemic attack). Aggrenox 200 mg/25 mg Capsule is a combination of two medicines: Aspirin and Dipyridamole. This medicine helps to maintain normal blood flow to the brain. It can prevent the formation of clots, thereby reducing the risk of stroke. 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aggrenox 200 mg/25 mg Capsule

  • Headache
  • Dizziness
  • Heartburn
  • Nausea
  • Indigestion
  • Diarrhea
  • Stomach pain
  • Fatigue 
  • Joint pains

Drug Warnings

Before taking Aggrenox 200 mg/25 mg Capsule , inform your doctor if you have stomach ulcers, bleeding problems, heart problems, hypotension (low blood pressure), and myasthenia gravis (a muscle disorder). The use of Aggrenox 200 mg/25 mg Capsule in children below 16 years with viral infections may lead to Reye’s syndrome (a life-threatening condition that causes liver and brain damage). Aggrenox 200 mg/25 mg Capsule may cause headaches during the initial days of therapy. Let your doctor know if the headache is severe. Aggrenox 200 mg/25 mg Capsule can increase the bleeding risk even due to a minor injury, so seek medical attention if you suffer any injury and have uncontrolled bleeding. Inform your doctor if you experience blood in your sputum or vomit, blood in urine, or dark-colored stools, as it can be a sign of stomach bleeding.

Drug Interactions

Drug-Drug Interactions: Aggrenox 200 mg/25 mg Capsule may interact with other medicines used to prevent blood clots (heparin and warfarin), a medicine used to treat fits, increased pressure in the eye, or altitude sickness (acetazolamide), anticancer agent (methotrexate), a medicine used to treat gout (probenecid), blood pressure-lowering medications including water pills, medicines used to treat Alzheimer’s disease, non-steroidal anti-inflammatory drugs (ibuprofen, naproxen, and diclofenac, etc.), oral diabetes medicines, and medicines used to treat fits (phenytoin and valproic acid).

Drug-Food Interactions: Do not consume alcohol as it can increase the risk of bleeding.

Drug-Disease Interactions: Aggrenox 200 mg/25 mg Capsule should not be used in patients with asthma, rhinitis (stuffy nose), and nasal polyps (painless, benign growths on the linings of the nose). It should be used with caution in patients with stomach ulcers, bleeding problems, heart problems, hypotension (low blood pressure), and myasthenia gravis (a muscle disorder).

Drug-Drug Interactions Checker List

  • HEPARIN
  • WARFARIN
  • ACETAZOLAMIDE
  • METHOTREXATE
  • PROBENECID
  • IBUPROFEN
  • DICLOFENAC
  • NAPROXEN
  • PHENYTOIN
  • VALPROIC ACID

Habit Forming

No

Diet & Lifestyle Advise

  • Include more green, leafy vegetables and other non-starchy vegetables (tomatoes, broccoli, and cauliflower, etc.) in your diet.
  • Eat strawberries, blueberries, blackberries, and nuts as they reduce inflammation in the brain.
  • Use olive oil for cooking purposes. It contains healthy fats that promote brain health. 
  • Eat whole grains such as oats, quinoa, and brown rice that are rich in nutrients.
  • Opt for fish oil or eat fish (preferably fatty fish like salmon, sardines, trout, and tuna) at least once a week. They are rich in omega-3 fatty acids that are essential for the normal functioning of the brain.
  • Avoid fried, processed, and packed foods.
  • Exercise regularly. It helps to maintain a normal weight and reduce cholesterol levels.
  • Quit alcohol intake and smoking.

Special Advise

  • Before undergoing surgery or dental procedure, inform your doctor that you are taking Aggrenox 200 mg/25 mg Capsule . This medicine increases the risk of bleeding and needs to be stopped before surgeries.
  • Aggrenox 200 mg/25 mg Capsule should be stopped at least 48 hours before undergoing a stress test for the heart.
  • Use reliable and effective contraception to prevent pregnancy while using Aggrenox 200 mg/25 mg Capsule .
  • Do not take any other medicines for pain, fever, or any other conditions without discussing with your doctor, as some over-the-counter medicines contain aspirin.

Disease/Condition Glossary

Stroke: It occurs when there is a decrease in blood supply to the brain due to blood clots or blood vessel's leakage. The decrease in blood supply leads to a decrease in oxygen and nutrients, resulting in brain cell's death. This condition leads to symptoms such as paralysis of the face, arm, or leg, slurred speech, headache, and difficulty in walking. Stroke requires immediate medical attention to prevent brain damage and long-term disability.

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Alcohol

Unsafe

Do not consume alcohol as it increases the risk of bleeding.

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Pregnancy

Unsafe

Aggrenox 200 mg/25 mg Capsule is not recommended for use in pregnant women as it may cause harmful effects in the unborn baby. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Aggrenox 200 mg/25 mg Capsule is not recommended for use in breastfeeding mothers as it may cause harmful effects in the nursing baby. Consult your doctor for further advice.

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Driving

Caution

Aggrenox 200 mg/25 mg Capsule may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

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Liver

Caution

Aggrenox 200 mg/25 mg Capsule should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Aggrenox 200 mg/25 mg Capsule should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Aggrenox 200 mg/25 mg Capsule should be used in children only if clinically needed. It should not be used in children less than 16 years of age who have viral infections.

Country of origin

Germany

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - AGG0007

Author Details

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FAQs

Aggrenox 200 mg/25 mg Capsule is used to prevent stroke in people who have had blood clots or had a mini-stroke.
Aggrenox 200 mg/25 mg Capsule contains Aspirin and Dipyridamole. Aspirin is a blood thinner. It has antithrombotic action that interferes with platelet functioning and does not let them stick together. Dipyridamole is an anticoagulant agent. It prevents the platelets from sticking together, thereby preventing the formation of blood clots. Together, Aggrenox 200 mg/25 mg Capsule can effectively reduce the risk of stroke.Â
The common side-effects of Aggrenox 200 mg/25 mg Capsule are headache, dizziness, heartburn, nausea, indigestion, diarrhea, and stomach pain. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Aggrenox 200 mg/25 mg Capsule should not be used in patients with asthma. This medicine contains aspirin which may induce an asthma attack or worsen the condition.
Aggrenox 200 mg/25 mg Capsule increases the risk of bleeding. So, be cautious while using sharp objects, knives, nail clippers, or engaging in contact sports such as football, basketball, or wrestling to avoid injuries. In addition, let your doctor know that you are taking Aggrenox 200 mg/25 mg Capsule before undergoing a surgery or dental procedure to prevent excessive bleeding.
You can take Aggrenox 200 mg/25 mg Capsule safely as long as your doctor has prescribed it to you. It is usually prescribed for the long-term to reduce the risk of stroke.

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