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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Afogatran 75 mg Capsule is an anticoagulant medicine used to prevent blood clot formation. This medicine prevents/treat conditions like deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), heart attack, and stroke. This medicine works by inhibiting the production of clotting factor Xa, also called thrombin. thereby preventing the conversion of fibrinogen to fibrin, a protein that helps prevent blood clot formation. Common side effects include bleeding, anaemia, nausea, stomach pain, and vomiting.
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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Afogatran 75 mg Capsule

Afogatran 75 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Afogatran 75 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Afogatran 75 mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Afogatran 75 mg Capsule as prescribed by your doctor. You are advised to take Afogatran 75 mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Afogatran 75 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Afogatran 75 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 75 mg Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 75 mg Capsule . Try not to stop taking this medicine on your own. Discontinuing Afogatran 75 mg Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Afogatran 75 mg Capsule

Prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Afogatran 75 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Afogatran 75 mg Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Afogatran 75 mg Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Afogatran 75 mg Capsule Works

Afogatran 75 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Afogatran 75 mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Afogatran 75 mg Capsule

  • Stomach pain
  • Vomiting
  • Bleeding
  • Anaemia (low number of red blood cells)
  • Nausea
  • Diarrhoea

What if I have taken an overdose of Afogatran 75 mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Afogatran 75 mg Capsule may include an increase in the risk of bleeding. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are known to be allergic to Afogatran 75 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 75 mg Capsule . Afogatran 75 mg Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 75 mg Capsule . You should inform the doctor that you are taking Afogatran 75 mg Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Afogatran 75 mg Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateKetoconazole
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Afogatran 75 mg Capsule 10's:
When Mifepristone is taken with Afogatran 75 mg Capsule 10's, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Afogatran 75 mg Capsule 10's is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateKetoconazole
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Coadministration of Ketoconazole and Afogatran 75 mg Capsule 10's may increase the blood levels and effects Afogatran 75 mg Capsule 10's. This may increase the risk of anemia and bleeding issues.

How to manage the interaction:
Although taking Ketoconazole and Afogatran 75 mg Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice paleness, exhaustion, dizziness, fainting, unusual bleeding or bruising, swelling, nausea, vomiting, blood in your urine or stools, headache, or weakness, consult a doctor. Do not discontinue any medication without consulting a doctor.
Dabigatran etexilateTolmetin
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Taking Afogatran 75 mg Capsule 10's with Tolmetin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 75 mg Capsule 10's with Tolmetin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateAspirin
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Using dabigatran with aspirin, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between aspirin and Afogatran 75 mg Capsule 10's, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting doctor.
Dabigatran etexilateRivaroxaban
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Co-administration of Afogatran 75 mg Capsule 10's and Rivaroxaban can increase the risk of bleeding, including severe blood loss.

How to manage the interaction:
Co-administration of Afogatran 75 mg Capsule 10's and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding, dizziness, tarry stools, coughing up or vomiting blood, or severe headache, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateCilostazol
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Co-administration of dabigatron etexilate with cilostazol can increase the risk or severity of bleeding.

How to manage the interaction:
Taking dabigatron etexilate with cilostazol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilatePiroxicam
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Coadministration of Piroxicam with Afogatran 75 mg Capsule 10's can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Afogatran 75 mg Capsule 10's, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePrimidone
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Taking Afogatran 75 mg Capsule 10's with Primidone can increase the risk of bleeding.

How to manage the interaction:
Taking Afogatran 75 mg Capsule 10's with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateDiclofenac
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilateEtodolac
Severe
How does the drug interact with Afogatran 75 mg Capsule 10's:
When Etodolac is taken with Afogatran 75 mg Capsule 10's may increase the risk or severity of bleeding and hemorrhage.

How to manage the interaction:
Taking Afogatran 75 mg Capsule 10's with Etodolac together can result in an interaction, but it can be taken if a doctor has advised it. However, if you happen to have any unusual bleeding or bruising, or other signs and symptoms of bleeding, such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-75MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-75MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Afogatran 75 mg Capsule 10's. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Afogatran 75 mg Capsule 10's treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Afogatran 75 mg Capsule Substitute

Substitutes safety advice
  • Dabigat 75 Capsule 10's

    by AYUR

    25.02per tablet
  • Dabiten 75 Capsule 10's

    by AYUR

    13.50per tablet
  • Dabifib 75 Capsule 10's

    by AYUR

    18.00per tablet
  • DABIREX 75MG CAPSULE 10'S

    by AYUR

    19.70per tablet
  • Dabirock-75Mg Capsule 10'S

    by AYUR

    18.45per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Afogatran 75 mg Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 75 mg Capsule . Your doctor will prescribe Afogatran 75 mg Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Afogatran 75 mg Capsule . Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Afogatran 75 mg Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 75 mg Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 75 mg Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Afogatran 75 mg Capsule is not recommended for children below the age of 18 years as the safety and efficacy of Afogatran 75 mg Capsule have not been established in children.

FAQs

Afogatran 75 mg Capsule is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).
Afogatran 75 mg Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.
Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Afogatran 75 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.
Taking Afogatran 75 mg Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 75 mg Capsule .
Afogatran 75 mg Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.
No, you are not recommended to stop taking Afogatran 75 mg Capsule without consulting your doctor as it may worsen the condition. Therefore, take Afogatran 75 mg Capsule for as long as your doctor has prescribed it.
Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.
You can take Afogatran 75 mg Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.
Take Afogatran 75 mg Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Afogatran 75 mg Capsule as long as your doctor has prescribed it for you.
You are recommended to avoid consumption of alcohol with Afogatran 75 mg Capsule as it may increase the risk of bleeding.
Hair loss is not a known side effect of Afogatran 75 mg Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.
It varies from person to person and depends on the conditions that we treat.
Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 75 mg Capsule . However, it is not recommended in patients with severe liver diseases.
Store in a cool and dry place away from sunlight. Keep Afogatran 75 mg Capsule out of the sight and reach of children.
Yes, bleeding is the main risk associated with Afogatran 75 mg Capsule treatment; patients should be monitored for signs of bleeding.
Afogatran 75 mg Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Afogatran 75 mg Capsule .
Common side effects of Afogatran 75 mg Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - AFO0016

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