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Bigatra 75mg Tablet

Bigatra 75mg Tablet

Prescription drug
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Manufacturer/Marketer

Aprica Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Bigatra 75mg Tablet

Bigatra 75mg Tablet belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Bigatra 75mg Tablet contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Bigatra 75mg Tablet helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Bigatra 75mg Tablet as prescribed by your doctor. You are advised to take Bigatra 75mg Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Bigatra 75mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Bigatra 75mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Bigatra 75mg Tablet. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Bigatra 75mg Tablet. Try not to stop taking this medicine on your own. Discontinuing Bigatra 75mg Tablet may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Bigatra 75mg Tablet

Prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism

Medicinal Benefits

Bigatra 75mg Tablet belongs to a class of drugs known as anticoagulants or blood thinners. Bigatra 75mg Tablet is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Bigatra 75mg Tablet works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bigatra 75mg Tablet

  • Stomach pain
  • Vomiting
  • Bleeding
  • Anaemia (low number of red blood cells)
  • Nausea
  • Diarrhoea

Drug Warnings

If you are known to be allergic to Bigatra 75mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Bigatra 75mg Tablet. Bigatra 75mg Tablet is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Bigatra 75mg Tablet. You should inform the doctor that you are taking Bigatra 75mg Tablet if you are due to undergo surgery. Avoid consumption of alcohol while taking Bigatra 75mg Tablet as it may increase the risk of stomach bleeding.

Drug Interactions

Drug-Drug Interactions: Bigatra 75mg Tablet may interact with medicines to reduce blood clotting (warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban), medicines to treat abnormal heartbeats  (amiodarone, dronedarone, quinidine, verapamil), medicines to treat fungal infections (ketoconazole, itraconazole), medicines to prevent organ rejection after transplantation (tacrolimus, cyclosporine) antiviral or HIV medicines (ritonavir, glecaprevir, pibrentasvir), antibiotics (rifampicin, clarithromycin), pain reliever (aspirin, ibuprofen, diclofenac), antiepileptic drugs (carbamazepine, phenytoin).

Drug-Food Interactions: Bigatra 75mg Tablet may interact with St. John’s wort, herbal medicine for depression.

Drug-Disease Interactions: Bigatra 75mg Tablet should be used with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAPAMIL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • INDINAVIR
  • RITONAVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • GLECAPREVIR
  • PIBRENTASVIR
  • IBUPROFEN
  • DICLOFENAC
  • PHENYTOIN
  • CARBAMAZEPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Special Advise

  • You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalized ratio) to analyze your blood clotting time.

  • In case you miss a dose of Bigatra 75mg Tablet, take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Disease/Condition Glossary

Thrombosis/Blood Clot: A blood clot can occur in any part of the body and can lead to a heart attack, stroke, or damage to organs. Blood clots can reach the arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. 

Deep vein thrombosis (blood clots in legs): It is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling. 

Pulmonary embolism (blood clots in the lung): It is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

Stroke (blood clots in the brain): It occurs when the supply of blood to part of your brain is stopped or reduced. This prevents brain tissue from getting nutrients and oxygen leading to the death of brain cells.

Heart attack: A heart attack means the death of heart tissue due to a shortage of blood supply to the heart muscles. This can occur when there is an accumulation of cholesterol or fat narrowing the heart's major veins or when other substances like a blood clot are blocking the flow of blood. 

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Bigatra 75mg Tablet as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Bigatra 75mg Tablet. Your doctor will prescribe Bigatra 75mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Bigatra 75mg Tablet. Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Bigatra 75mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Bigatra 75mg Tablet. However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Bigatra 75mg Tablet. However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Bigatra 75mg Tablet is not recommended for children below the age of 18 years as the safety and efficacy of Bigatra 75mg Tablet have not been established in children.

Country of origin

India
Other Info - BI82299

Author Details

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FAQs

Bigatra 75mg Tablet is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).
Bigatra 75mg Tablet is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.
Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Bigatra 75mg Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.
Taking Bigatra 75mg Tablet during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Bigatra 75mg Tablet.
Bigatra 75mg Tablet may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.
No, you are not recommended to stop taking Bigatra 75mg Tablet without consulting your doctor as it may worsen the condition. Therefore, take Bigatra 75mg Tablet for as long as your doctor has prescribed it.
Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.
You can take Bigatra 75mg Tablet with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.
Take Bigatra 75mg Tablet as prescribed by your doctor. Depending on your medical conditions, you are advised to take Bigatra 75mg Tablet as long as your doctor has prescribed it for you.
You are recommended to avoid consumption of alcohol with Bigatra 75mg Tablet as it may increase the risk of bleeding.
Hair loss is not a known side effect of Bigatra 75mg Tablet. However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.
It varies from person to person and depends on the conditions that we treat.
Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Bigatra 75mg Tablet. However, it is not recommended in patients with severe liver diseases.
Store in a cool and dry place away from sunlight. Keep Bigatra 75mg Tablet out of the sight and reach of children.
Yes, bleeding is the main risk associated with Bigatra 75mg Tablet treatment; patients should be monitored for signs of bleeding.
Bigatra 75mg Tablet is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Bigatra 75mg Tablet.
Common side effects of Bigatra 75mg Tablet may include bleeding, anaemia, nausea, stomach pain, and vomiting.

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