Acabrunat 100 Capsule 30's

Acabrunat 100 Capsule is a tyrosine kinase inhibitor or cancer growth inhibitor that is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy (cancer), as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Cancer is caused by a genetic mutation that causes our cells to divide uncontrollably and spread into neighbouring tissues.

Acabrunat 100 Capsule contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that transmit signals to cells, telling them to grow and divide. Acalabrutinib inhibits these signals to cancer cells. Cells die when their signals are disrupted. This could help to slow the progression of the cancer.

To treat your condition effectually, continue using Acabrunat 100 Capsule for as long as your doctor has prescribed it. The most common adverse reactions are anaemia (lack of blood), neutropenia (low count of neutrophils), upper respiratory tract infection, thrombocytopenia (Low platelet level), headache, diarrhoea, and musculoskeletal pain. You should talk to your doctor if you persistently experience these side effects.

It is recommended not to use if you are hypersensitive to any component present in Acabrunat 100 Capsule and suffer from Severe Hepatic Impairment. Acabrunat 100 Capsule can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Acabrunat 100 Capsule . Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Acabrunat 100 Capsule is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy, as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Acabrunat 100 Capsule contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that send signals to cells, directing them to grow and divide. Acalabrutinib blocks these signals to cancer cells. Cancer cells die when their signals are interrupted. This could help to delay the progression of the cancer.

• Feeling sick (nausea)
• Being sick (vomiting)
• Fatigue
• Anaemia (lack of blood)
• Neutropenia (low count of neutrophils)
• Upper respiratory tract infection
• Thrombocytopenia (low platelet level)
• Headache
• Diarrhea
• Musculoskeletal pain (myalgia)
• Abdominal pain
• Fatigue (tiredness)
• Bruising
• Rash
• Haemorrhage (bleeding)
• Epistaxis (nosebleed)

Before taking the Acabrunat 100 Capsule , inform your doctor about all your medical conditions, sensitivities, and medications you are using. If you are a woman capable of having children, you should use an effective method of contraception during Acalabrutinib treatment and for at least one week after the last dose. If you are a man, you should use a barrier method of contraception to prevent your partner from becoming pregnant while taking Acalabrutinib and for at least one week after the last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements.

Drug-Drug Interactions: Acabrunat 100 Capsule may interact with Blood thinner medications (e.g. abciximab, apixaban), Vaccinations (e.g. BCG vaccine), Nonsteroidal Anti-inflammatory drugs (e.g. bromfenac, ibuprofen), HIV medications (e.g. cobicistat), Anticancer medications (e.g. dasatinib), antifungal medications (e.g. fluconazole) and medicines decreasing the amount of acid made in the stomach (e.g. esomeprazole).

Drug-Food Interactions: Avoid the intake of alcoholic beverages, grapefruit and grapefruit juice.

Drug-Disease Interactions: Acabrunat 100 Capsule interacts with disease conditions, including arrhythmias, bleeding disorder, kidney or liver illness, infections (Bacterial/Fungal/Protozoal/Viral), Immunodeficiency, and Bone Marrow Depression/Low Blood Counts.

• ABCIXIMAB
• APIXABAN
• BCG VACCINE
• BROMFENAC
• IBUPROFEN
• COBICISTAT
• DASATINIB
• ESOMEPRAZOLE
• FLUCONAZOLE

• After your treatment begins, several dietary adjustments can help you control side effects.
• Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
• Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Performing yoga may also help in improving both physical and mental health.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get optimal sleep; rest well.
• Avoid smoking and alcohol consumption.
• Avoid fast, fried, processed meats, refined carbs, and added sugars.

• Keep all of your doctor's and laboratory appointments.
• Pregnancy testing is recommended prior to starting treatment with Acabrunat 100 Capsule .

Cancer: Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Mantle Cell lymphoma (MCL): Mantle Cell lymphoma (MCL) is an aggressive, rare form of non-Hodgkin lymphoma (NHL) that arises from cells originating in the “mantle zone.” The mantle zone is the outer ring of small lymphocytes surrounding the centre of a lymphatic nodule.