Acalnib 100 mg Capsule 30's
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Acalnib 100 mg Capsule 30's is a tyrosine kinase inhibitor or cancer growth inhibitor that is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy (cancer), as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Cancer is caused by a genetic mutation that causes our cells to divide uncontrollably and spread into neighbouring tissues.
Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that transmit signals to cells, telling them to grow and divide. Acalabrutinib inhibits these signals to cancer cells. Cells die when their signals are disrupted. This could help to slow the progression of the cancer.
To treat your condition effectually, continue using Acalnib 100 mg Capsule 30's for as long as your doctor has prescribed it. The most common adverse reactions are anaemia (lack of blood), neutropenia (low count of neutrophils), upper respiratory tract infection, thrombocytopenia (Low platelet level), headache, diarrhoea, and musculoskeletal pain. You should talk to your doctor if you persistently experience these side effects.
It is recommended not to use if you are hypersensitive to any component present in Acalnib 100 mg Capsule 30's and suffer from Severe Hepatic Impairment. Acalnib 100 mg Capsule 30's can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Acalnib 100 mg Capsule 30's. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.
Acalnib 100 mg Capsule 30's is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy, as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that send signals to cells, directing them to grow and divide. Acalabrutinib blocks these signals to cancer cells. Cancer cells die when their signals are interrupted. This could help to delay the progression of the cancer.
Before taking the Acalnib 100 mg Capsule 30's, inform your doctor about all your medical conditions, sensitivities, and medications you are using. If you are a woman capable of having children, you should use an effective method of contraception during Acalabrutinib treatment and for at least one week after the last dose. If you are a man, you should use a barrier method of contraception to prevent your partner from becoming pregnant while taking Acalabrutinib and for at least one week after the last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements.
Drug-Drug Interactions: Acalnib 100 mg Capsule 30's may interact with Blood thinner medications (e.g. abciximab, apixaban), Vaccinations (e.g. BCG vaccine), Nonsteroidal Anti-inflammatory drugs (e.g. bromfenac, ibuprofen), HIV medications (e.g. cobicistat), Anticancer medications (e.g. dasatinib), antifungal medications (e.g. fluconazole) and medicines decreasing the amount of acid made in the stomach (e.g. esomeprazole).
Drug-Food Interactions: Avoid the intake of alcoholic beverages, grapefruit and grapefruit juice.
Drug-Disease Interactions: Acalnib 100 mg Capsule 30's interacts with disease conditions, including arrhythmias, bleeding disorder, kidney or liver illness, infections (Bacterial/Fungal/Protozoal/Viral), Immunodeficiency, and Bone Marrow Depression/Low Blood Counts.
Cancer: Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.
Mantle Cell lymphoma (MCL): Mantle Cell lymphoma (MCL) is an aggressive, rare form of non-Hodgkin lymphoma (NHL) that arises from cells originating in the “mantle zone.” The mantle zone is the outer ring of small lymphocytes surrounding the centre of a lymphatic nodule.
Alcohol
Unsafe
Avoid alcohol consumption while on treatment with Acalnib 100 mg Capsule 30's.
Pregnancy
Unsafe
Acalnib 100 mg Capsule 30's should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.
Breast Feeding
Unsafe
Acalnib 100 mg Capsule 30's should not be used in breastfeeding. Discuss with your doctor if you have any concerns.
Driving
Caution
Acalnib 100 mg Capsule 30's does not influence the ability to drive or use machines. However, go only if you are alert, as the Acalnib 100 mg Capsule 30's may cause tiredness in some people.
Liver
Caution
Avoid using Acalnib 100 mg Capsule 30's in patients with severe hepatic impairment. The safety of Acalnib 100 mg Capsule 30's has not been evaluated in patients with moderate or severe hepatic impairment. So, caution should be exercised while using Acalnib 100 mg Capsule 30's in patients with liver impairment. If you have a pre-existing or a history of liver disease, inform your doctor before taking the Acalnib 100 mg Capsule 30's. Your doctor will weigh the benefits and potential risks before prescribing Acalnib 100 mg Capsule 30's.
Kidney
Caution
Caution should be exercised while using Acalnib 100 mg Capsule 30's in patients with kidney impairment. If you have a pre-existing or a history of kidney disease, inform your doctor before taking the Acalnib 100 mg Capsule 30's. Your doctor will weigh the benefits and potential risks before prescribing Acalnib 100 mg Capsule 30's.
Children
Caution
Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.
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