apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

AKT-3 Kit is used to treat tuberculosis (TB) caused by the bacteria mycobacterium tuberculin. It prevents or kills the bacteria and prevents its spread. It may cause common side effects like nausea, vomiting, fever, dark-coloured urine, sweating, and increased saliva. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Read more
rxMedicinePrescription drug

Whats That

tooltip
Consult Doctor

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About AKT-3 Kit

AKT-3 Kit belongs to the group of antibiotics called 'antituberculosis agents' used to treat tuberculosis (TB) caused by the bacteria mycobacterium tuberculin. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce toxins which can damage tissue and make you sick. Tuberculosis (TB) usually attacks your lungs and can also spread to the brain and spine. Common signs and symptoms of TB include fever, cough (sometimes blood-tinged), weight loss, and night sweats.

AKT-3 Kit contains Rifampicin, Ethambutol, and Isoniazid. Rifampicin inhibits DNA synthesis (a process required for bacterial growth and division). On the other hand, Ethambutol and Isoniazid prevent bacterial cell wall (outer covering) synthesis, which is necessary for growth. This ultimately prevents or kills the bacteria and prevents its spread.

AKT-3 Kit should be taken as directed by the doctor. You may experience common side effects like nausea, vomiting, fever, dark-coloured urine, sweating, and increased saliva. Everyone need not undergo the above symptoms. If any discomfort occurs from this medicine, consult your doctor.

People with liver and kidney diseases should take AKT-3 Kit only after consulting with a doctor. Pregnant women and breastfeeding mothers should take AKT-3 Kit as instructed by the doctor. Do not take this medicine with alcohol, which causes drowsiness. While on the medication, your doctor advises some diagnostic and laboratory tests to know the effects of drugs on the body. Use of AKT-3 Kit may also affect oral contraceptive pills, so if you are using any, please consult a doctor and ask for some other birth control methods. You may experience dark-coloured urine and yellowing of teeth after using AKT-3 Kit. However, these are harmless symptoms and may go after stopping AKT-3 Kit.

Uses of AKT-3 Kit

Treatment of Tuberculosis (TB)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

AKT-3 Kit is an antibiotic active against the mycobacterium strain of bacteria, which causes TB infection. Rifampicin, Ethambutol, and Isoniazid prevent the bacteria's growth by interfering with the cell wall and DNA (the genetic material of bacteria) required to survive the bacteria. AKT-3 Kit is active against Mycobacterium bacteria which causes TB and leprosy.

How AKT-3 Kit Works

AKT-3 Kit contains Rifampicin, Ethambutol, and Isoniazid. Rifampicin inhibits DNA synthesis (a process required for bacterial growth and division). On the other hand, Ethambutol and Isoniazid prevent bacterial cell wall (outer covering) synthesis, which is necessary for growth. This ultimately prevents or kills the bacteria and prevents its spread.

Storage

Store in a cool and dry place away from sunlight

Side Effects of AKT-3 Kit

  • Nausea
  • Vomiting
  • Fever
  • Rash Dark-coloured urine
  • Increased salivation (drooling)

What if I have taken an overdose of AKT-3 Kit

Do not take more than the prescribed dose of AKT-3 Kit as it may cause overdose. The symptoms of overdose include dizziness/fainting/lightheadedness when getting up suddenly from a lying or sitting position, confusion, blurred vision, fast/pounding/irregular heartbeat, slurring of speech, severe sleepiness, low blood pressure or seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

People with liver and kidney diseases should take AKT-3 Kit only after consulting with a doctor. Pregnant women and breastfeeding mothers should take AKT-3 Kit as instructed by the doctor. Do not take this medicine with alcohol, which causes drowsiness. While on the medication, your doctor advises some diagnostic and laboratory tests to know the effects of drugs on the body. Use of AKT-3 Kit may also affect oral contraceptive pills, so please consult a doctor and ask for some other birth control methods if you are using any. You may experience dark-coloured urine and yellowing of teeth after using AKT-3 Kit. However, these are harmless symptoms and may go after stopping AKT-3 Kit.

Drug-Drug Interactions

verifiedApollotooltip
RifampicinPirfenidone
Critical
RifampicinVoriconazole
Critical

Drug-Drug Interactions

Login/Sign Up

RifampicinPirfenidone
Critical
How does the drug interact with AKT-3 Kit 1's:
Taking pirfenidone with AKT-3 Kit 1's can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and AKT-3 Kit 1's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with AKT-3 Kit 1's:
Taking Voriconazole with AKT-3 Kit 1's can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with AKT-3 Kit 1's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with AKT-3 Kit 1's:
Taking saquinavir with AKT-3 Kit 1's can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and AKT-3 Kit 1's, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinRanolazine
Critical
How does the drug interact with AKT-3 Kit 1's:
When ranolazine is taken with AKT-3 Kit 1's, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and AKT-3 Kit 1's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinIndinavir
Critical
How does the drug interact with AKT-3 Kit 1's:
When Indinavir is taken with AKT-3 Kit 1's, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and AKT-3 Kit 1's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDarunavir
Critical
How does the drug interact with AKT-3 Kit 1's:
Taking darunavir with AKT-3 Kit 1's can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and AKT-3 Kit 1's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
IsoniazidLovastatin
Critical
How does the drug interact with AKT-3 Kit 1's:
When Lovastatin is taken with AKT-3 Kit 1's, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking AKT-3 Kit 1's with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with AKT-3 Kit 1's:
When Lomitapide is taken with AKT-3 Kit 1's, AKT-3 Kit 1's may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking AKT-3 Kit 1's with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidRegorafenib
Critical
How does the drug interact with AKT-3 Kit 1's:
When AKT-3 Kit 1's is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with AKT-3 Kit 1's is not recommended, it taken can be taken if prescribed by the doctor.
RifampicinAtorvastatin
Severe
How does the drug interact with AKT-3 Kit 1's:
Taking atorvastatin with AKT-3 Kit 1's can decrease the blood levels of atorvastatin, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between atorvastatin and AKT-3 Kit 1's, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
RIFAMPICIN-450MG+ETHAMBUTOL-800MG+ISONIAZID-300MGTyramine-containing food, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

Login/Sign Up

RIFAMPICIN-450MG+ETHAMBUTOL-800MG+ISONIAZID-300MGTyramine-containing food, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consuming Tyramine containing food and Caffeine with AKT-3 Kit 1's can increase the risk of toxicity. Avoid consuming Tyramine-containing food and Caffeine with AKT-3 Kit 1's. Contact a doctor immediately if you experience any symptoms such as headache, diaphoresis, flushing, diarrhea, nausea, vomiting, tachycardia, dyspnea, and hypotension.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help improve the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve a cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

AKT-3 Kit Substitute

Substitutes safety advice
  • TRAC 3 TABLET

    5.48per tablet
  • Rhe FD Tablet 6's

    20.03per tablet
  • Rhe Kit Tablet 2's

    10.35per tablet
  • MONTO 3 KIT TABLET

    2.25per tablet
  • RF-HE Tablet Kit

    13.50per tablet
bannner image

Alcohol

Unsafe

Consuming alcohol and AKT-3 Kit causes flushing, increased heartbeat, chest pain, nausea, thirst and low blood pressure. So avoid the use of alcohol with AKT-3 Kit.

bannner image

Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Safe if prescribed

Consult your doctor, and there is no substantial research yet on the use of AKT-3 Kit in breastfeeding/nursing mothers.

bannner image

Driving

Caution

AKT-3 Kit may affect your ability to drive as it produces drowiness and sleep. So, it should not be taken before driving a motor vehicle.

bannner image

Liver

Caution

Limited information was available for the use of AKT-3 Kit in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using AKT-3 Kit in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Limited information was available for the use of AKT-3 Kit in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using AKT-3 Kit in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

AKT-3 Kit is not recommended for use in children as its safety and efficacy have not been established.

FAQs

AKT-3 Kit is used to treat tuberculosis (TB) caused by the bacteria Mycobacterium tuberculin. It prevents or kills the bacteria and prevents its spread.
No, AKT-3 Kit decreases the action of birth control pills. So, use other contraceptive devices or methods to avoid unwanted pregnancies. Discuss with your doctor before taking this medicine.
It is best to take AKT-3 Kit on an empty stomach 1 hour before or 2 hours after meals.
The full form of DOTS is (Directly Observed Therapy Short Term). It is a defined treatment regimen initiated by the Government to cure tuberculosis. The initial treatment phase consists of 8 weeks of the four drugs, namely: Isoniazid (H), Rifampicin (R), Pyrazinamide (Z) and Ethambutol (E). Then, the continuation phase should consist of the three drugs: Isoniazid, Rifampicin and Ethambutol, which should be given for another 16 weeks.
Yes, it may take at least 6-8 months for the treatment of TB. Remember, you should regularly take DOTS therapy as instructed by the doctor or DOTS worker provided by the government agency.
Do not Panic, as AKT-3 Kit can cause bright red-orange colour urine, faeces, saliva, sputum, sweat, and tear. It won't occur as soon as you stop the use of drugs.
Taking AKT-3 Kit combination tablet is convenient, helps you take your medication correctly, and reduces mistakes in administering.
The duration of taking AKT-3 Kit for getting relief from the symptoms can vary depending on the individual's health condition. Generally, noticeable improvements can occur within a few days to a week after starting treatment. Follow your doctor's instructions regarding dose and duration and complete the full course as prescribed.
You will know the treatment is working when you start to feel better, experience a reduction in symptoms like coughing, fever, and fatigue, and if follow-up tests show improvement. Complete the full course of treatment even if you start feeling better.
To ensure you are fully cured of tuberculosis, your doctor will conduct follow-up tests like sputum cultures or chest X-rays. Complete the entire course of treatment and attend all follow-up appointments to ensure the infection is fully cured.
AKT-3 Kit can make birth control pills less effective. Use an alternative method of contraception, such as condoms or diaphragms,while taking this medication. Discuss with your doctor for personalized advice.
Store AKT-3 Kit at room temperature, away from moisture and heat. Keep out of reach of children and pets.
AKT-3 Kit may cause discoloration of the urine in some individuals as it is a common side effect. However, this effect vanishes over time as the medication adapts to the body. If this symptom becomes more uncomfortable and worsens please consult a doctor for relief.
No, don't discontinue taking AKT-3 Kit even if you feel well. Complete the full course of treatment as prescribed by your doctor to ensure the infection is fully cleared. If you are having any concerns please discuss them with your doctor.
AKT-3 Kit can cause visual impairment, primarily due to Ethambutol in its composition. It can lead to optic neuritis, causing decreased vision, blind spots, and colour vision changes. Have regular eye tests and report any vision changes to your doctor immediately.
The common side effects of AKT-3 Kit that may occur in some individuals are nausea, vomiting, fever, dark-coloured urine, sweating, and increased saliva. However, these symptoms vanish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - AKT0001

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button