COFENAC GEL is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, contusions (bruises), post-traumatic pain, and low back pain. It contains diclofenac diethylamine, which works by blocking the effect of chemical messengers that cause pain and inflammation. In some cases, this medicine may cause side effects such as application site reactions like itching, irritation, redness, and burning sensation.